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Impaired dynamics of precapillary sphincters and pericytes at first-order capillaries predict reduced neurovascular function in the aging mouse brain

Changsi Cai ca0064c629 Update 'README.md' 2 年 前
All_Data_v2.xlsx ff086f32cd Upload files to '' 2 年 前
AmiraDataAnalysis.rar add77ce1fe Upload files to '' 2 年 前
DiameterMeasurement.rar bff0d72370 Upload files to '' 2 年 前
IHCAnalysis.rar ffa271c229 Upload files to '' 2 年 前
LICENSE 65f3091f58 Initial commit 2 年 前
MathModel.rar 134533eb78 Upload files to '' 2 年 前
README.md ca0064c629 Update 'README.md' 2 年 前

README.md

NATAGING-L01111B

Impaired dynamics of precapillary sphincters and pericytes at first-order capillaries predict reduced neurovascular function in the aging mouse brain

This folder contains both the raw data and code for data analysis.

All raw data related to the publications are collected in the excel file 'All_Data_v2'

There are four rar code packages for data analysis. (1) AmiraDataAnalysis.rar

Please unzip the file and load 'RawDataAnl_Vol3_Allcount3_NEW.m' into MATLAB.
This code helps analyze the Amira 3D vasculature shown in Figure 4.

(2) DiameterMeasurement.rar

Please unzip the file and load 'VesselDiameter_ByArea_GUI_MAIN.m' into MATLAB.
This code helps analyze vessel diameter change in 4D (xyzt) scanning.

(3) IHCAnalysis.rar

Please unzip the file and load 'GliaTrans_POI_GUI_MAIN.m' into MATLAB.
This code helps analyze the alpha-SMA density, pericyte and endothelial cell density from the immunohistochemical images in Figure 1.

(4) MathModel.rar

Please unzip the file and load 'amirachangsianal.py'into Python.
This code makes math model of existing vasculatures to estimate the blood pressure and flow at each vessel segment.