ChangsiCai/NATAGING-L01111B: Impaired dynamics of precapillary sphincters and pericytes at first-order capillaries predict reduced neurovascular function in the aging mouse brain @ ca0064c629b89a7560f7cca86230edf7c4f1f6e9

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Changsi Cai ca0064c629 Update 'README.md'		2 years ago
All_Data_v2.xlsx	ff086f32cd Upload files to ''	2 years ago
AmiraDataAnalysis.rar	add77ce1fe Upload files to ''	2 years ago
DiameterMeasurement.rar	bff0d72370 Upload files to ''	2 years ago
IHCAnalysis.rar	ffa271c229 Upload files to ''	2 years ago
LICENSE	65f3091f58 Initial commit	2 years ago
MathModel.rar	134533eb78 Upload files to ''	2 years ago
README.md	ca0064c629 Update 'README.md'	2 years ago

Changsi Cai ca0064c629 Update 'README.md'

2 years ago

All_Data_v2.xlsx

ff086f32cd Upload files to ''

2 years ago

AmiraDataAnalysis.rar

add77ce1fe Upload files to ''

2 years ago

DiameterMeasurement.rar

bff0d72370 Upload files to ''

2 years ago

IHCAnalysis.rar

ffa271c229 Upload files to ''

2 years ago

LICENSE

65f3091f58 Initial commit

2 years ago

MathModel.rar

134533eb78 Upload files to ''

2 years ago

README.md

ca0064c629 Update 'README.md'

2 years ago

NATAGING-L01111B

Impaired dynamics of precapillary sphincters and pericytes at first-order capillaries predict reduced neurovascular function in the aging mouse brain

This folder contains both the raw data and code for data analysis.

All raw data related to the publications are collected in the excel file 'All_Data_v2'

There are four rar code packages for data analysis. (1) AmiraDataAnalysis.rar

Please unzip the file and load 'RawDataAnl_Vol3_Allcount3_NEW.m' into MATLAB. This code helps analyze the Amira 3D vasculature shown in Figure 4.

(2) DiameterMeasurement.rar

Please unzip the file and load 'VesselDiameter_ByArea_GUI_MAIN.m' into MATLAB. This code helps analyze vessel diameter change in 4D (xyzt) scanning.

(3) IHCAnalysis.rar

Please unzip the file and load 'GliaTrans_POI_GUI_MAIN.m' into MATLAB. This code helps analyze the alpha-SMA density, pericyte and endothelial cell density from the immunohistochemical images in Figure 1.

(4) MathModel.rar

Please unzip the file and load 'amirachangsianal.py'into Python. This code makes math model of existing vasculatures to estimate the blood pressure and flow at each vessel segment.