ChangsiCai/NATAGING-L01111B: Impaired dynamics of precapillary sphincters and pericytes at first-order capillaries predict reduced neurovascular function in the aging mouse brain @ ca0064c629b89a7560f7cca86230edf7c4f1f6e9

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Changsi Cai ca0064c629 Update 'README.md'		преди 2 години
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README.md	ca0064c629 Update 'README.md'	преди 2 години

Changsi Cai ca0064c629 Update 'README.md'

преди 2 години

All_Data_v2.xlsx

ff086f32cd Upload files to ''

преди 2 години

AmiraDataAnalysis.rar

add77ce1fe Upload files to ''

преди 2 години

DiameterMeasurement.rar

bff0d72370 Upload files to ''

преди 2 години

IHCAnalysis.rar

ffa271c229 Upload files to ''

преди 2 години

LICENSE

65f3091f58 Initial commit

преди 2 години

MathModel.rar

134533eb78 Upload files to ''

преди 2 години

README.md

ca0064c629 Update 'README.md'

преди 2 години

NATAGING-L01111B

Impaired dynamics of precapillary sphincters and pericytes at first-order capillaries predict reduced neurovascular function in the aging mouse brain

This folder contains both the raw data and code for data analysis.

All raw data related to the publications are collected in the excel file 'All_Data_v2'

There are four rar code packages for data analysis. (1) AmiraDataAnalysis.rar

Please unzip the file and load 'RawDataAnl_Vol3_Allcount3_NEW.m' into MATLAB. This code helps analyze the Amira 3D vasculature shown in Figure 4.

(2) DiameterMeasurement.rar

Please unzip the file and load 'VesselDiameter_ByArea_GUI_MAIN.m' into MATLAB. This code helps analyze vessel diameter change in 4D (xyzt) scanning.

(3) IHCAnalysis.rar

Please unzip the file and load 'GliaTrans_POI_GUI_MAIN.m' into MATLAB. This code helps analyze the alpha-SMA density, pericyte and endothelial cell density from the immunohistochemical images in Figure 1.

(4) MathModel.rar

Please unzip the file and load 'amirachangsianal.py'into Python. This code makes math model of existing vasculatures to estimate the blood pressure and flow at each vessel segment.