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SW_lab
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Anesthesia_CA1
DOI
10.12751/g-node.lkx6kk
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Calcium imaging and electrophysiology data from hippocampal CA1 during wakefulness and under various general anesthetics

Strom: e94819395d
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Anesthesia_CA1
Andrey Formozov e94819395d repo_figures added for gifs 2 rokov pred
Anesthesia 1d24963b3f gin commit from andrey-UX510UXK 3 rokov pred
Sleep a48f286f93 gin commit from andrey-UX510UXK 2 rokov pred
data_colab 7985671ffc gin commit from andrey-UX510UXK 3 rokov pred
meta_data d50601e98b gin commit from andrey-UX510UXK 2 rokov pred
repo_figures e94819395d repo_figures added for gifs 2 rokov pred
validation 659436b2f9 gin commit from andrey-UX510UXK 2 rokov pred
LICENSE 69d0ea48c9 Initial commit 4 rokov pred
README.md 2bcaf9a340 updated 2 rokov pred

README.md

Anesthesia_CA1

This repository contains data related to the article "Anesthetics fragment hippocampal network activity, alter spine dynamics and affect memory consolidation" (https://www.biorxiv.org/content/10.1101/2020.06.05.135905v1).

We provide calcium imaging and electrophysiology data from hippocampal CA1 during wakefulness, sleep and under various general anesthetics (Isoflurane, Keta/Xyl and MMF).

Awake Isoflurane Keta/Xyl MMF

Following the structure of the repository, the dataset contains:

  • LFP and SUA recordings from 4 mice under Isoflurane, Keta/Xyl and MMF anesthesia (electrophysiology folder)
  • 189 distinct 2-photon calcium imaging recordings from 7 different mice under Isoflurane, Keta/Xyl and MMF anesthesia (calcium imaging folder)
  • LFP and SUA recordings in awake and sleep conditions (with sleep scoring) from 7 and 4 mice respectively (Sleep Data/LFP and Sleep Data/SUA folders)
  • 74 distinct 2-photon calcium imaging recordings from 3 mice in awake and sleep conditions (Sleep Data/calcium imaging folder)

This repository contains electrophysiological data and processed calcium imaging recordings. Raw calcium imaging recordings are available in another repository.

Data structure info

Most data structure should be self explanatory / inferrable from the description in the manuscript, but some useful information is provided in the respective "meta_data" excel files.

Miscellaneous