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This repository contains data related to the article "Anesthetics fragment hippocampal network activity, alter spine dynamics and affect memory consolidation" (https://www.biorxiv.org/content/10.1101/2020.06.05.135905v1).
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-We provide calcium imaging and electrophysiology data from hippocampal CA1 during wakefulness, sleep and under various general anesthetics.
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+We provide calcium imaging and electrophysiology data from hippocampal CA1 during wakefulness, sleep and under various general anesthetics (Isoflurane, Keta/Xyl and MMF).
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+**Awake** | **Isoflurane** | **Keta/Xyl** | **MMF**
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+:-------------------------:|:-------------------------:|:-------------------------:|:-------------------------:
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+ |  |  | 
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Following the structure of the repository, the dataset contains:
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- LFP and SUA recordings from 4 mice under Isoflurane, Keta/Xyl and MMF anesthesia (electrophysiology folder)
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- 189 distinct 2-photon calcium imaging recordings from 7 different mice under Isoflurane, Keta/Xyl and MMF anesthesia (calcium imaging folder)
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- LFP and SUA recordings in awake and sleep conditions (with sleep scoring) from 7 and 4 mice respectively (Sleep Data/LFP and Sleep Data/SUA folders)
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- 74 distinct 2-photon calcium imaging recordings from 3 mice in awake and sleep conditions (Sleep Data/calcium imaging folder)
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+This repository contains electrophysiological data and processed calcium imaging recordings. Raw calcium imaging recordings are available in [another repository](https://gin.g-node.org/SW_lab/Calcium_imaging_CA1_raw).
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## Data structure info
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Most data structure should be self explanatory / inferrable from the description in the manuscript, but some useful information is provided in the respective "meta_data" excel files.
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@@ -18,4 +26,4 @@ Most data structure should be self explanatory / inferrable from the description
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- information about the numpy calcium imaging files can be found in the suite2p documentation page (https://suite2p.readthedocs.io/en/latest/)
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- for LFP data, only the CA1 reversal channel is provided
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- LFP data has a sampling rate of 320 Hz and has been band-pass filtered in the 0.1-160 Hz range
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-- code used for analysis/stats and stats dataset can be found at https://github.com/mchini/Yang_Chini_et_al and https://github.com/OpatzLab/HanganuOpatzToolbox
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+- code used for the analysis and statistics together with stats-dataset can be found at https://github.com/mchini/Yang_Chini_et_al and https://github.com/OpatzLab/HanganuOpatzToolbox
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