README.md 2.4 KB
Data set - Cortical neuron number in schizophrenia with focus on area 24: a post-mortem case-control study
Stereological data accompanying the study:
Gaus, R., Popal, M., Heinsen, H. et al. Reduced cortical neuron number and neuron density in schizophrenia with focus on area 24: a post-mortem case–control study. Eur Arch Psychiatry Clin Neurosci (2022). https://doi.org/10.1007/s00406-022-01513-6
The repository contains a table (raw_stereology_data.xlsx) with clinical characteristics and raw stereological estimates from the brains of 13 male patients with schizophrenia and 13 age-matched male controls.
If you plan to use this data for a publication, please inform us about it and don’t forget to cite the source of the data.
Description of data
Each row in the table represents one individual hemisphere. The table contains the following columns:
| Column | Description | Unit |
|---|---|---|
subject |
Subject ID | |
code |
Subject code | |
excl |
see below* | |
excl_cgm |
see below* | |
diagnosis |
Control: 0, Patient: 1 |
|
hemisphere |
Left or right hemisphere | |
age |
Age of subject | years |
pmi |
Post-mortem interval | hours |
fix |
Fixation time | days |
cgm_vol |
Volume of whole CGM | cm3 |
cgm_nn |
Total neuron number in whole CGM | x109 |
cgm_nd |
Total neuron density in whole CGM | x106 / cm3 |
area24_vol |
Volume of whole area 24 | cm3 |
area24_nn |
Total neuron number in whole area 24 | x106 |
area24_nd |
Total neuron density in whole area 24 | x106 / cm3 |
area24layer5_vol |
Volume of layer V of area 24 | cm3 |
area24layer5_nn |
Total neuron number in layer V of area 24 | x106 |
area24layer5_nd |
Total neuron density in layer V of area 24 | x106 / cm3 |
ven_number |
VEN number in layer V of area 24 | x103 |
ven_density |
VEN density in layer V of area 24 | x103 / cm3 |
*All hemispheres where columns excl / excl_cgm carry the value 1 were excluded from the statistical analysis for all outcome variables / only the CGM-related outcome variables (cgm_vol, cgm_nn, cgm_nd) due to missing sections.
CGM: cortical gray matter; VEN: von Economo neuron