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+# Metadata for DOI registration according to DataCite Metadata Schema 4.1.
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+# For detailed schema description see https://doi.org/10.5438/0014
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+
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+## Required fields
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+
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+# The main researchers involved. Include digital identifier (e.g., ORCID)
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+# if possible, including the prefix to indicate its type.
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+authors:
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+ -
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+ firstname: "Vincenzo"
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+ lastname: "Fiore"
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+ affiliation: "Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA"
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+ id: "ORCID:0000-0002-4865-5482"
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+ -
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+ firstname: "Ann-Cathrin"
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+ lastname: "Guertler"
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+ affiliation: "School of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, TX 75080, USA"
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+ -
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+ firstname: "Ju-Chi"
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+ lastname: "Yu"
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+ affiliation: "School of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, TX 75080, USA"
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+ -
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+ firstname: "Chandana"
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+ lastname: "Tatineni"
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+ affiliation: "The Texas College of Osteopathic Medicine at University of North Texas Health Science Center, Fort Worth, TX 76107, USA"
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+ -
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+ firstname: "Xiaosi"
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+ lastname: "Gu"
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+ affiliation: "Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA"
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+
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+
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+# A title to describe the published resource.
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+title: "A change of mind: globus pallidus activity and effective connectivity during changes in choice selections"
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+
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+# Additional information about the resource, e.g., a brief abstract.
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+description: |
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+ The basal ganglia are a group of interconnected subcortical nuclei that plays a key role in multiple motor and cognitive processes, in a close interplay with several cortical regions.
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+ Two conflicting theories postulate that the basal ganglia pathways can either foster or suppress the cortico-striatal output or, alternatively, they can stabilise or destabilise the cortico-striatal circuit dynamics.
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+ These different approaches significantly impact the understanding of observable behaviours and cognitive processes in healthy, as well as clinical populations.
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+ We investigated the predictions of these models in healthy participants (N=28), using dynamic causal modelling of fMRI BOLD activity to estimate time- and context-dependent changes in the indirect pathway effective connectivity, in association with repetitions or changes of choice selections.
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+ We used two multi-option tasks that required the participants to adapt to uncontrollable environmental changes, by performing sequential choice selections, with and without value-based feedbacks.
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+ We found that, irrespective of the task, the trials that were characterised by changes in choice selections (switch trials) were associated with a neural response that mostly overlapped with a network commonly described for the encoding of uncertainty.
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+ More interestingly, dynamic causal modelling and family-wise model comparison identified with high likelihood a directed causal relation from the external to the internal part of the globus pallidus (i.e. the short indirect pathway in the basal ganglia), in association with the switch trials.
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+ This finding supports the hypothesis that the short indirect pathway in the basal ganglia drives instability in the network dynamics, resulting in changes in choice selection.
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+
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+# Lit of keywords the resource should be associated with.
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+# Give as many keywords as possible, to make the resource findable.
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+keywords:
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+ - Computational Neuroscience
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+ - DCM
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+ - effective connectivity
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+ - Basal Ganglia
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+ - Globus Pallidus
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+
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+# License information for this resource. Please provide the license name and/or a link to the license.
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+# Please add also a corresponding LICENSE file to the repository.
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+license:
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+ name: "Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"
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+ url: "https://creativecommons.org/licenses/by-nc-nd/4.0/"
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+
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+
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+
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+## Optional Fields
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+
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+# Funding information for this resource.
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+# Separate funder name and grant number by comma.
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+funding:
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+ - "NIDA, R01DA043695"
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+ - "NIDA, R21DA049243"
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+ - "NIMH, R21MH120789"
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+ - "NIMH, R01MH124115"
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+ - "NIMH, R01MH122611"
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+
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+
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+# Related publications. reftype might be: IsSupplementTo, IsDescribedBy, IsReferencedBy.
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+# Please provide digital identifier (e.g., DOI) if possible.
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+# Add a prefix to the ID, separated by a colon, to indicate the source.
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+# Supported sources are: DOI, arXiv, PMID
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+# In the citation field, please provide the full reference, including title, authors, journal etc.
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+references:
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+ -
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+ id: "doi:10.xxx/zzzz"
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+ reftype: "IsSupplementTo"
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+ citation: "Citation1"
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+
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+
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+# Resource type. Default is Dataset, other possible values are Software, DataPaper, Image, Text.
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+resourcetype: Dataset
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+
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+# Do not edit or remove the following line
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+templateversion: 1.2
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