Globus_Pallidus_activity_and_DCM/datacite.yml

# Metadata for DOI registration according to DataCite Metadata Schema 4.1.
# For detailed schema description see https://doi.org/10.5438/0014

## Required fields

# The main researchers involved. Include digital identifier (e.g., ORCID)
# if possible, including the prefix to indicate its type.
authors:
  -
    firstname: "Vincenzo"
    lastname: "Fiore"
    affiliation: "Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA"
    id: "ORCID:0000-0002-4865-5482"
  -
    firstname: "Ann-Cathrin"
    lastname: "Guertler"
    affiliation: "School of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, TX 75080, USA"
  -
    firstname: "Ju-Chi"
    lastname: "Yu"
    affiliation: "School of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, TX 75080, USA"
  -
    firstname: "Chandana"
    lastname: "Tatineni"
    affiliation: "The Texas College of Osteopathic Medicine at University of North Texas Health Science Center, Fort Worth, TX 76107, USA"
  -
    firstname: "Xiaosi"
    lastname: "Gu"
    affiliation: "Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029-5674, USA"
  
  
# A title to describe the published resource.
title: "A change of mind: globus pallidus activity and effective connectivity during changes in choice selections"

# Additional information about the resource, e.g., a brief abstract.
description: |
  The basal ganglia are a group of interconnected subcortical nuclei that plays a key role in multiple motor and cognitive processes, in a close interplay with several cortical regions. 
  Two conflicting theories postulate that the basal ganglia pathways can either foster or suppress the cortico-striatal output or, alternatively, they can stabilise or destabilise the cortico-striatal circuit dynamics.
  These different approaches significantly impact the understanding of observable behaviours and cognitive processes in healthy, as well as clinical populations. 
  We investigated the predictions of these models in healthy participants (N=28), using dynamic causal modelling of fMRI BOLD activity to estimate time- and context-dependent changes in the indirect pathway effective connectivity, in association with repetitions or changes of choice selections. 
  We used two multi-option tasks that required the participants to adapt to uncontrollable environmental changes, by performing sequential choice selections, with and without value-based feedbacks. 
  We found that, irrespective of the task, the trials that were characterised by changes in choice selections (switch trials) were associated with a neural response that mostly overlapped with a network commonly described for the encoding of uncertainty.
  More interestingly, dynamic causal modelling and family-wise model comparison identified with high likelihood a directed causal relation from the external to the internal part of the globus pallidus (i.e. the short indirect pathway in the basal ganglia), in association with the switch trials. 
  This finding supports the hypothesis that the short indirect pathway in the basal ganglia drives instability in the network dynamics, resulting in changes in choice selection.

# Lit of keywords the resource should be associated with.
# Give as many keywords as possible, to make the resource findable.
keywords:
  - Computational Neuroscience
  - DCM
  - effective connectivity
  - Basal Ganglia
  - Globus Pallidus

# License information for this resource. Please provide the license name and/or a link to the license.
# Please add also a corresponding LICENSE file to the repository.
license:
  name: "Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"
  url: "https://creativecommons.org/licenses/by-nc-nd/4.0/"



## Optional Fields

# Funding information for this resource.
# Separate funder name and grant number by comma.
funding:
  - "NIDA, R01DA043695"
  - "NIDA, R21DA049243"
  - "NIMH, R21MH120789"
  - "NIMH, R01MH124115"
  - "NIMH, R01MH122611"


# Related publications. reftype might be: IsSupplementTo, IsDescribedBy, IsReferencedBy.
# Please provide digital identifier (e.g., DOI) if possible.
# Add a prefix to the ID, separated by a colon, to indicate the source.
# Supported sources are: DOI, arXiv, PMID
# In the citation field, please provide the full reference, including title, authors, journal etc.
references:
  -
    id: "doi:10.xxx/zzzz"
    reftype: "IsSupplementTo"
    citation: "Citation1"


# Resource type. Default is Dataset, other possible values are Software, DataPaper, Image, Text.
resourcetype: Dataset

# Do not edit or remove the following line
templateversion: 1.2