Gaus_etal_2021_Neuron_numbers_decreased_in_schizophrenia/README.md

Gaus_etal_2021_Neuron_numbers_decreased_in_schizophrenia

Stereologic data accompanying the study:

Richard Gaus, Melanie Popal, Helmut Heinsen, Andrea Schmitt, Peter Falkai, Patrick R. Hof, Christoph Schmitz, Alisa Vollhardt (2021) Neuron numbers are decreased in the whole cerebral cortex and in layer V of area 24 in schizophrenia

The repository contains a table (raw_stereology_data.xlsx) with clinical characteristics and raw stereological estimates of volume, cell counts, and cell densities in the whole cerebral cortex, whole area 24, and layer V of area 24 in the brains of 13 male patients with schizophrenia and 13 age-matched male controls.

The table contains the following columns:

Column	Description	Unit
subject	Text	Text

Units of estimates are as follows:

• CGM volume (cgm_vol): cm³
• CGM neuron number (cgm_nn): x10⁹
• CGM neuron density (cgm_nd): x10⁶ / cm³
• Area 24 volume (area24_vol): cm³
• Area 24 neuron number (area24_nn): x10⁶
• Area 24 neuron density (area24_vol): x10⁶ / cm³
• Area 24 layer V volume: cm³
• Area 24 layer V neuron number: x10⁶
• Area 24 layer V neuron density: x10⁶ / cm³
• VEN number: x10³
• VEN density: x10³ / cm³

All hemispheres where columns excl / excl_cgm carry the value 1 were excluded from the statistical analysis for all outcome variables / only the CGM-related outcome variables due to missing sections.

If you plan to use this data for a publication, please inform us about it and don’t forget to cite the source of the data.