Stereologic data accompanying the study "Neuron numbers are decreased in the whole cerebral cortex and in layer V of area 24 in schizophrenia" by Gaus et al. 2021

Richard Gaus ccad4f838b 'LICENSE' ändern 3 months ago
LICENSE ccad4f838b 'LICENSE' ändern 3 months ago
README.md 8235c3e3bf 'README.md' ändern 3 months ago
datacite.yml 244607fabd 'datacite.yml' ändern 3 months ago
raw_stereology_data.xlsx e963ebef1c Dateien hochladen nach '' 3 months ago

README.md

Gaus_etal_2021_Neuron_numbers_decreased_in_schizophrenia

Stereological data accompanying the study:

Richard Gaus, Melanie Popal, Helmut Heinsen, Andrea Schmitt, Peter Falkai, Patrick R. Hof, Christoph Schmitz, Alisa Vollhardt (2021) Neuron numbers are decreased in the whole cerebral cortex and in layer V of area 24 in schizophrenia

The repository contains a table (raw_stereology_data.xlsx) with clinical characteristics and raw stereological estimates from the brains of 13 male patients with schizophrenia and 13 age-matched male controls.

If you plan to use this data for a publication, please inform us about it and don’t forget to cite the source of the data.

Description of data

Each row in the table represents one individual hemisphere. The table contains the following columns:

Column Description Unit
subject Subject ID
code Subject code
excl see below*
excl_cgm see below*
diagnosis Control: 0, Patient: 1
hemisphere Left or right hemisphere
age Age of subject years
pmi Post-mortem interval hours
fix Fixation time days
cgm_vol Volume of whole CGM cm3
cgm_nn Total neuron number in whole CGM x109
cgm_nd Total neuron density in whole CGM x106 / cm3
area24_vol Volume of whole area 24 cm3
area24_nn Total neuron number in whole area 24 x106
area24_nd Total neuron density in whole area 24 x106 / cm3
area24layer5_vol Volume of layer V of area 24 cm3
area24layer5_nn Total neuron number in layer V of area 24 x106
area24layer5_nd Total neuron density in layer V of area 24 x106 / cm3
ven_number VEN number in layer V of area 24 x103
ven_density VEN density in layer V of area 24 x103 / cm3

*All hemispheres where columns excl / excl_cgm carry the value 1 were excluded from the statistical analysis for all outcome variables / only the CGM-related outcome variables (cgm_vol, cgm_nn, cgm_nd) due to missing sections.

CGM: cortical gray matter; VEN: von Economo neuron

datacite.yml
Title Data set - Neuron numbers are decreased in the whole cerebral cortex and in layer V of area 24 in schizophrenia
Authors Gaus,Richard;Chair of Neuroanatomy, Institute of Anatomy, Faculty of Medicine, LMU Munich, Munich, Germany;ORCID:0000-0001-5999-0174
Popal,Melanie;Chair of Neuroanatomy, Institute of Anatomy, Faculty of Medicine, LMU Munich, Munich, Germany
Heinsen,Helmut;Morphological Brain Research Unit, Department of Psychiatry, University of Würzburg, Würzburg, Germany; Department of Radiology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil;ORCID:0000-0002-4688-4441
Schmitt,Andrea;Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany;ORCID:0000-0002-5426-4023
Falkai,Peter;Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany;ORCID:0000-0003-2873-8667
Hof,Patrick R.;Nash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA;ORCID:0000-0002-3208-1154
Schmitz,Christoph;Chair of Neuroanatomy, Institute of Anatomy, Faculty of Medicine, LMU Munich, Munich, Germany;ORCID:0000-0002-4065-1241
Vollhardt,Alisa;Chair of Neuroanatomy, Institute of Anatomy, Faculty of Medicine, LMU Munich, Munich, Germany
Description Data set accompanying Gaus et al. (2021) Neuron numbers are decreased in the whole cerebral cortex and in layer V of area 24 in schizophrenia
License CC BY-SA 4.0 (https://creativecommons.org/licenses/by-sa/4.0/)
References
Funding
Keywords schizophrenia
anterior cingulate
area 24
von Economo neurons
stereology
Resource Type Dataset