Data for Figure 3
Fig. 3A-B.mat
Z-scored firing rate of L5 pyramidal neurons in expert and naive rats during the microstimulation task.
Normalized by responses during pre-stimulus period [-1 0] s.
Conditions
| Condition |
Description |
| Expert |
Animals after >3 days of training. |
| Naive |
Animals without pairing sessions. |
Entries
| Entry |
Description |
<cond>_PSTHz |
Z-scores of firing rate responses. |
<cond>_sorted |
Index for sorting cells as in figures. Sorted by mean z-score of [0.2 0.5] s bins. |
binsize |
Binsize for z-scored PSTHs. 50 ms. |
preStim |
Pre-stimulus window. 1 s. |
postStim |
Post-stimulus window. 3 s. |
Fig. 3C.mat
PSTHs of three distinctive subpopulations of L5 pyramidal neurons in expert rats.
[cellNum x binNum]
binsize: 100 ms
pre-stimulus window: [-2 0] s
post-stimulus window: [0 2] s
Conditions
| Condition |
Description |
| ON |
Cells with post-stimulus firing rate in [0.3 0.4] s period above mean + 3 x standard deviation (SD). |
| OFF |
Cells with post-stimulus firing rate in [0.3 0.4] s period below mean - 3 x standard deviation (SD). |
| NR |
Rest of the cells. |
Entries
| Entry |
Description |
<cond>_PSTH |
PSTHs of firing rate responses. |
<cond>_bPSTH |
PSTHs of burst rate responses. |
Fig. 3G.mat
Motion-corrected peri-stimulus calcium transients (ΔF/F0) of three distinctive subpopulations of L5 apical dendrites in expert mice. Frame rate at 58.62 Hz. Pre-stimulus 1 s and post-stimulus 3.1 s window.
Conditions
| Condition |
Description |
| ON |
Dendrites with post-stimulus calcium transients above mean + 3 x standard deviation (SD). |
| OFF |
Dendrites with post-stimulus calcium transients below mean - 3 x standard deviation (SD). |
| NR |
Rest of the dendrites. |
Fields
| Field |
Description |
avgTrace |
Average peri-stimulus calcium traces (ΔF/F0) for each dendrite. |
Fig. 3I&J.mat
Effects of optogenetic and pharmacological manipulations of dendritic activity on learning of the microstimulation detection task.
Conditions
| Condition |
Description |
| Ctrl |
Animals after pairing sessions. No virus expression, but CNO was injected into L1 of S1. |
| BacL1 |
Animals after pairing sessions. GABAb receptor agonist baclofen was applied to L1 of S1. |
| SST |
SST-cre x ChR2 mice after pairing sessions. Somatostatin-positive interneurons were optogenetically activated by LED illumination on the surface of S1. |
Entries
| Entry |
Description |
<cond>_cumvals |
The cumulative learning curve statistics for the condition. Values on row N (N=1, ... 100) represents the cumulative learning score of each animal after N trials. |
<cond> |
The normalized learning scores for each animal belonging to the condition. |
