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+load('PooledCellsData.mat')
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+%% Connected dots - Hit trials
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+figure
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+
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+subplot(121)
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+ConnectedDots2 (Control_hit_freq(:,1), Control_hit_freq(:,2)) % Unclear_hit_freq(:,1)])
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+%set(gca,'XTickLabel',{'Control (n=41)','hM4Di (n=40)'})
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+ylabel('Spike rate (Hz)')
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+title('Control')
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+[p h] = signrank (Control_hit_freq(:,1), Control_hit_freq(:,2)) % Unclear_hit_freq(:,1)])
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+hold on
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+text(1.2, 20, ['p = ', num2str(p)])
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+
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+subplot(122)
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+ConnectedDots2 (newDREADD_hit_freq(:,1), newDREADD_hit_freq(:,2)) % Unclear_hit_freq(:,1)])
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+%set(gca,'XTickLabel',{'Control (n=42)','hM4Di (n=26)'})
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+ylabel('Spike rate (Hz)')
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+title('hM4Di')
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+[p h] = signrank (newDREADD_hit_freq(:,1), newDREADD_hit_freq(:,2)) % Unclear_hit_freq(:,1)])
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+hold on
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+text(1.2, 20, ['p = ', num2str(p)])
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+ylim([0 25])
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+
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+figure
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+
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+subplot(121)
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+ConnectedDots2 (Control_hit_burst(:,1), Control_hit_burst(:,2)) % Unclear_hit_burst(:,1)])
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+%set(gca,'XTickLabel',{'Control (n=42)','hM4Di (n=26)'})
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+ylabel('Burst rate (Hz)')
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+title('Control')
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+[p h] = signrank (Control_hit_burst(:,1), Control_hit_burst(:,2)) % Unclear_hit_burst(:,1)])
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+hold on
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+text(1.2, 2, ['p = ', num2str(p)])
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+
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+subplot(122)
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+ConnectedDots2 (newDREADD_hit_burst(:,1), newDREADD_hit_burst(:,2)) % Unclear_hit_burst(:,1)])
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+%set(gca,'XTickLabel',{'Control (n=42)','hM4Di (n=26)'})
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+ylabel('Burst rate (Hz)')
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+title('hM4Di')
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+[p h] = signrank (newDREADD_hit_burst(:,1), newDREADD_hit_burst(:,2)) % Unclear_hit_burst(:,1)])
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+hold on
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+text(1.2, 2, ['p = ', num2str(p)])
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+ylim([0 2.5])
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+
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+%% Connected Dots - miss trials
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+figure
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+
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+subplot(121)
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+ConnectedDots2 (Control_miss_freq(:,1), Control_miss_freq(:,2)) % Unclear_miss_freq(:,1)])
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+%set(gca,'XTickLabel',{'Control (n=41)','hM4Di (n=40)'})
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+ylabel('Spike rate (Hz)')
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+title('Control')
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+ylim ([0 25])
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+[p h] = signrank (Control_miss_freq(:,1), Control_miss_freq(:,2)) % Unclear_miss_freq(:,1)])
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+hold on
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+text(1.2, 20, ['p = ', num2str(p)])
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+
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+subplot(122)
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+ConnectedDots2 (newDREADD_miss_freq(:,1), newDREADD_miss_freq(:,2)) % Unclear_miss_freq(:,1)])
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+%set(gca,'XTickLabel',{'Control (n=42)','hM4Di (n=26)'})
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+ylabel('Spike rate (Hz)')
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+title('hM4Di')
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+[p h] = signrank (newDREADD_miss_freq(:,1), newDREADD_miss_freq(:,2)) % Unclear_miss_freq(:,1)])
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+hold on
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+text(1.2, 20, ['p = ', num2str(p)])
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+ylim([0 25])
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+
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+figure
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+
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+subplot(121)
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+ConnectedDots2 (Control_miss_burst(:,1), Control_miss_burst(:,2)) % Unclear_miss_burst(:,1)])
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+%set(gca,'XTickLabel',{'Control (n=42)','hM4Di (n=26)'})
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+ylabel('Burst rate (Hz)')
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+title('Control')
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+ylim([0 2.5])
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+[p h] = signrank (Control_miss_burst(:,1), Control_miss_burst(:,2)) % Unclear_miss_burst(:,1)])
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+hold on
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+text(1.2, 2, ['p = ', num2str(p)])
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+
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+subplot(122)
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+ConnectedDots2 (newDREADD_miss_burst(:,1), newDREADD_miss_burst(:,2)) % Unclear_miss_burst(:,1)])
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+%set(gca,'XTickLabel',{'Control (n=42)','hM4Di (n=26)'})
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+ylabel('Burst rate (Hz)')
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+title('hM4Di')
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+[p h] = signrank (newDREADD_miss_burst(:,1), newDREADD_miss_burst(:,2)) % Unclear_miss_burst(:,1)])
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+hold on
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+text(1.2, 2, ['p = ', num2str(p)])
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+ylim([0 2.5])
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+
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+
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+%% Difference
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+
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+Control_hit_freq(:,3) = Control_hit_freq(:,2) - Control_hit_freq(:,1);
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+newDREADD_hit_freq(:,3) = newDREADD_hit_freq(:,2) - newDREADD_hit_freq(:,1);
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+Unclear_hit_freq(:,3) =Unclear_hit_freq(:,2) - Unclear_hit_freq(:,1);
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+
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+figure
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+subplot(121)
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+PlotAllDataPoints (Control_hit_freq(:,3), newDREADD_hit_freq(:,3) )
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+set(gca,'XTickLabel',{'Control (n=42)','hM4Di (n=26)'})
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+ylabel('Post - Pre')
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+title('Spike rate change')
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+
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+[p h] = ranksum (Control_hit_freq(:,3), newDREADD_hit_freq(:,3))
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+
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+hold on
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+text(1.2, 10, ['p = ', num2str(p)])
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+
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+subplot(122)
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+PlotAllDataPoints (abs(Control_hit_freq(:,3)), abs(newDREADD_hit_freq(:,3)) )
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+set(gca,'XTickLabel',{'Control (n=42)','hM4Di (n=26)'})
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+ylabel('|Post - Pre|')
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+title('Spike rate Absolute change')
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+
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+[p h] = ranksum (abs(Control_hit_freq(:,3)), abs(newDREADD_hit_freq(:,3)))
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+
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+hold on
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+text(1.2, 10, ['p = ', num2str(p)])
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+
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+% Bursts
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+Control_hit_burst(:,3) = Control_hit_burst(:,2) - Control_hit_burst(:,1);
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+newDREADD_hit_burst(:,3) = newDREADD_hit_burst(:,2) - newDREADD_hit_burst(:,1);
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+Unclear_hit_burst(:,3) =Unclear_hit_burst(:,2) - Unclear_hit_burst(:,1);
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+
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+
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+figure
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+subplot(121)
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+PlotAllDataPoints (Control_hit_burst(:,3), newDREADD_hit_burst(:,3) )
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+set(gca,'XTickLabel',{'Control (n=42)','hM4Di (n=26)'})
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+ylabel('Post - Pre')
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+title('Burst rate change')
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+
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+[p h] = ranksum (Control_hit_burst(:,3), newDREADD_hit_burst(:,3))
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+
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+hold on
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+text(1.2, 1, ['p = ', num2str(p)])
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+
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+
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+subplot(122)
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+PlotAllDataPoints (abs(Control_hit_burst(:,3)), abs(newDREADD_hit_burst(:,3)) )
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+set(gca,'XTickLabel',{'Control (n=42)','hM4Di (n=26)'})
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+ylabel('|Post - Pre|')
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+title('Spike rate Absolute change')
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+
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+[p h] = ranksum (abs(Control_hit_burst(:,3)), abs(newDREADD_hit_burst(:,3)))
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+
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+hold on
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+text(1.2, 1, ['p = ', num2str(p)])
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+%% Relative change
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+Control_baseline = mean(Control_hit_burst(:,1));
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+newDREADD_baseline = mean(newDREADD_hit_burst(:,1));
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+
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+Control_hit_burst(:,4) = Control_hit_burst(:,3)./Control_baseline;
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+newDREADD_hit_burst(:,4) = newDREADD_hit_burst(:,3)./newDREADD_baseline;
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+
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+[p h] = ranksum (Control_hit_burst(:,4), newDREADD_hit_burst(:,4))
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+
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+figure
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+PlotAllDataPoints (Control_hit_burst(:,4).*100, newDREADD_hit_burst(:,4).*100 )
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+set(gca,'XTickLabel',{'Control (n=42)','hM4Di (n=26)'})
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+ylabel('Relative change (%)')
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+title('Burst')
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+
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+
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+%% Post stim
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+figure
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+
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+subplot(121)
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+PlotAllDataPoints (Control_hit_freq(:,2), newDREADD_hit_freq(:,2) )
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+set(gca,'XTickLabel',{'Control (n=41)','hM4Di (n=41)'})
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+ylabel('Spike rate (Hz)')
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+title('Hit - Post stimulation')
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+
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+[p h] = ranksum (Control_hit_freq(:,2), newDREADD_hit_freq(:,2))
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+
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+hold on
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+text(1.2, 10, ['p = ', num2str(p)])
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+
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+subplot(122)
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+PlotAllDataPoints (Control_miss_freq(:,2), newDREADD_miss_freq(:,2) )
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+set(gca,'XTickLabel',{'Control (n=18)','hM4Di (n=17)'})
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+ylabel('Spike rate (Hz)')
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+title('Miss - Post stimulation')
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+
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+[p h] = ranksum (Control_miss_freq(:,2), newDREADD_miss_freq(:,2))
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+
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+hold on
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+text(1.2, 8, ['p = ', num2str(p)])
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+ylim([0 25])
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+
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+%% Bar wit error
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+N1 = size(Control_hit_freq,1)
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+Control_Avg_hitFreq = nanmean(Control_hit_freq);
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+Control_SEM_hitFreq = nanstd(Control_hit_freq,1)./sqrt(N1);
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+Control_Avg_hitBurst = nanmean(Control_hit_burst) ;
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+Control_SEM_hitBurst = nanstd(Control_hit_burst,1)./sqrt(N1);
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+
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+N2 = size(newDREADD_hit_freq,1)
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+newDREADD_Avg_hitFreq = nanmean(newDREADD_hit_freq);
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+newDREADD_SEM_hitFreq = nanstd(newDREADD_hit_freq,1)./sqrt(N2);
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+newDREADD_Avg_hitBurst = nanmean(newDREADD_hit_burst) ;
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+newDREADD_SEM_hitBurst = nanstd(newDREADD_hit_burst,1)./sqrt(N2);
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+
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+
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+% %% Plotting
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+figure
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+subplot(2,1,1)
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+varargout = barwitherr([Control_SEM_hitFreq; newDREADD_SEM_hitFreq],[Control_Avg_hitFreq; newDREADD_Avg_hitFreq])
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+set(gca,'XTickLabel',{'Control (n=41)','hM4Di (n=40)'})
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+ylabel('Firing rate (Hz)')
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+ylim([0 5])
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+
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+title('hit trials')
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+legend({'preStim', 'postStim'})
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+
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+subplot(2,1,2)
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+varargout = barwitherr([Control_SEM_hitBurst; newDREADD_SEM_hitBurst],[Control_Avg_hitBurst;newDREADD_Avg_hitBurst])
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+set(gca,'XTickLabel',{'Control (n=41)','hM4Di (n=40)'})
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+ylabel('Burst rate (Hz)')
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+
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+
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+%% Violin plot
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+figure
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+violin(Control_hit_burst);
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+set(gca, 'XTick',[1,2],'XTickLabel',{'PreStim', 'PostStim'})
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+title('Control')
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+
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+figure
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+violin(newDREADD_hit_burst);
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+set(gca, 'XTick',[1,2],'XTickLabel',{'PreStim', 'PostStim'})
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+title('hM4Di')
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