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4D multi-channel neonatal brain altas


This repository contains a 4D parametrized atlas multi-channel atlas of the normal term neonatal brain development during 37-44 weeks PMA presented in (Uus et al., 2021). The atlas was constructed from 170 normal term MRI datasets from the dHCP project.

The atlas includes:

  • 4D fitted structural MRI channels (common 0.75mm and unbiased 0.6mm space): T1w, T2w, T1w/T2w
  • 4D fitted diffusion MRI channels (common 0.75mm and unbiased 0.6mm space): DTI(FA, MD, RD), ODF(ODF, TDI), NODDI(FICVF, FISO, ODI), average DWI, DKI(MK), microFA
  • parcellation maps (M-CRIB-WM-based WM ROIs, high rate change "gamma" ROIs and the original dHCP tissue ROIs)
  • Gompertz model gamma maps (outputs of 4D fitting corresponding to the signal change rate in time)
  • transformations from 37 to 44 weeks PMA timepoints (affine in MIRTK format and nonlinear warps in MRtrix3 format)


In case you found this resource useful please give appropriate credit to the atlas:

Uus, Alena, Irina Grigorescu, Maximilian Pietsch, Dafnis Batalle, Daan Christiaens, Emer Hughes, Jana Hutter, Lucilio Cordero Grande, Anthony N. Price, Jacques-Donald Tournier, Mary A. Rutherford, Serena J. Counsell, Joseph V Hajnal, A. David Edwards, and Maria Deprez. 2021. “Multi-Channel 4D Parametrized Atlas of Macro- and Microstructural Neonatal Brain Development.” Frontiers in Neuroscience 15:721 : https://doi.org/10.3389/fnins.2021.661704