Autism Risk Gene Cul3 Alters Neuronal Morphology via Caspase-3 Activity in Mouse Hippocampal Neurons

Qiangqiang Xia 527f59236b Update 'datacite.yml'		1 week ago
Figure 1 WB.prism	74b11a89c1 Figure 1	1 week ago
Figure 2 Sholl and Spine Analysis.prism	80a5bd91c6 Figure 2	1 week ago
Figure 3 Caspase-3 Activity.prism	6d19a8cef8 Figure 3	1 week ago
Figure 4 Sholl and Spine Analysis - Caspase-3 Inhibitor.prism	33d65c5132 Figure 4	1 week ago
Figure 5 PSD95 and vGluT1.prism	74825bd69e Figure 5	1 week ago
Figure 6 Gehpyrin and vGAT.prism	66b915b4f6 Figure 6	1 week ago
Figure 7 Inhibitory synapse-Caspase-3 Inhibitor.prism	2d6af0a2fa Figure 7	1 week ago
Figure S1-Supplementary figure S1.prism	d0a39640ce Figure S1	1 week ago
Graphical Abstract.PNG	2185d91175 Graphical Abstract	1 week ago
LICENSE	1c28313dc8 Initial commit	6 months ago
README.md	036d2582ed Update 'README.md'	1 week ago
Supplementary information.PDF	dc32b82043 Supplementary information	1 week ago
Supplementary table 1-Detailed Statistics.XLSX	ac9b8dd8a2 Supplementary table 1-Detailed Statistics	1 week ago
datacite.yml	527f59236b Update 'datacite.yml'	1 week ago

FICN-1320784

Title: Autism Risk Gene Cul3 Alters Neuronal Morphology via Caspase-3 Activity in Mouse Hippocampal Neurons

Description: This is a original dataset repository for manuscript # 1320784 published at Frontiers in Cellular Neuroscience, including the Western blot (Figure 1 and Figure S1) and immunocytochemistry tests in primary neuronal cultures (Figure 2-8).

The figure files format are .prism, which can be open by Prism GraphPad: https://www.graphpad.com/features; these figure files include the raw data of these Western blots and immunocytochemistry tests at Data tables; statistical analysis at Results; graphs plotted from these raw data at Graphs; figures made from these grpahs at Layouts.

Supplementary material is a .word that can be opened by Office Word, which including the figure legends of Figure S1.

please contact qqxia@uab.edu if you have any further questions on these data.

datacite.yml
Title	Autism Risk Gene Cul3 Alters Neuronal Morphology via Caspase-3 Activity in Mouse Hippocampal Neurons
Authors	Xia,Qiangqiang;University of Alabama at Birmingham;ORCID:0000-0002-8490-6437 Powell,Criag M.;University of Alabama at Birmingham;ORCID:0000-0001-5451-2165
Description	Cul3 regulates the formation or maintenance of cell morphology, GABAergic synaptic puncta, and neuronal viability in developing hippocampal neurons in culture.
License	Creative Commons CC0 1.0 Public Domain Dedication (https://creativecommons.org/publicdomain/zero/1.0/)
References	Xia Q-q, Singh A, Wang J, Xuan ZX, Singer JD and Powell CM (2024) Autism risk gene Cul3 alters neuronal morphology via caspase-3 activity in mouse hippocampal neurons. Front. Cell. Neurosci. 18:1320784. doi: 10.3389/fncel.2024.1320784 [https://doi.org/10.3389/fncel.2024.1320784] (IsSupplementTo)
Funding	National Institute of Mental Health (NIMH), R01 MH113948 Civitan International Research Center, Emerging Scholar Award
Keywords	cullin-3 dendrite axon spine synapse caspase-3
Resource Type	Dataset

README.md

FICN-1320784