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README.md

Normal 3D cervix models for fetal MRI

This repository contains 3D structural T2w po 3T and 0.55T MRI atlases of the normal cervix anatomy cretated at King's College London from 3D D/SVR T2w reconstructed images.

Structural 3D T2w MRI altases of the normal cervix anatomy

The 2 population-averaged cervix atlases were created from two acquisition protocols from 81 (0.55T, TE=105ms) and 61 (3T, TE=180ms) 3D DSVR reconstructed images (Uus et al., 2020: https://doi.org/10.1109/tmi.2020.2974844) of normal control subjects without reported anomalies. The atlases were generated in MIRTK toolbox in 5 iterations using rigid, affine and non-rigid registration followed by averaging with Laplacian sharpening with 0.8mm isotropic resolution. The atlases were then parcellated by 3D segmentation network into 3 layers: endocervical canal, subglandular zone, outer stroma.

Publication is coming soon!

License

The fetal MRI atlases are distributed under the terms of the Creative Commons CC0 1.0 Universal license.

Acknowledgements

We thank everyone who was involved in acquisition and analysis of the datasets at the Department of Perinatal Imaging and Health at Kings College London and St Thomas' Hospital. We thank all participants and their families.

This work was supported by NIHR Advanced Fellowship awarded to Lisa Story [NIHR30166], by the Wellcome Trust, Sir Henry Wellcome Fellowship to Jana Hutter, [201374/Z/16/Z], by the UKRI, FLF to Jana Hutter [MR/T018119/1], MRC grant [MR/W019469/1], the Wellcome/ EPSRC Centre for Medical Engineering at King’s College London [WT 203148/Z/16/Z], the NIHR Clinical Research Facility (CRF) at Guy’s and St Thomas’ and by the National Institute for Health Research Biomedical Research Centre based at Guy’s and St Thomas’ NHS Foundation Trust and King’s College London.

The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health.

In case you found this resource useful please give appropriate credit to the atlases:

3D fetal MRI cervix atlas repository: https://gin.g-node.org/kcl_cdb/cervix_mri_atlas