Data repository for
Fiber Counts and Architecture of the Human Dorsal Penile Nerve
from
Tunckol et al. 2023 (Scientific Reports)
https://gin.g-node.org/elephant/Tunckol
elephant
827f350db0
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Data repository for Fiber Counts and Architecture of the Human Dorsal Penile Nerve from Tunckol et al. 2023 (Scientific Reports)
Bernstein Center for Computational Neuroscience Berlin, Humboldt-Universität zu Berlin, Philippstr. 13, Haus 6, 10115 Berlin
The data provided are:
Further data and explanation are available upon request from michael.brecht@bccn-berlin.de
| datacite.yml | |
|---|---|
| Title | Fiber Counts and Architecture of the Human Dorsal Penile Nerve |
| Authors |
Tunckol,Elçin;Bernstein Center for Computational Neuroscience;ORCID:0000-0001-2345-6789
FamilyName2,GivenName2;Affiliation2;ResearcherID:X-1234-5678 FamilyName3,GivenName3 |
| Description | The human penis transmits behaviorally important sensory information via the dorsal penile nerve, but we lack a detailed understanding of the penile sensory innervation. To address this issue, we quantified and analyzed the architecture of the dorsal penile nerves of five male subjects who donated their body. We stained the sensory fibers in penile dorsal nerve with anti-neurofilament-H antibody, and identify myelinated axons with Luxol fast blue staining. Furthermore, we visualized nerve bundles as they travel along the shaft of the penis by performing micro CT scans after counterstaining penes with Iodide. Our results show that the dorsal penile nerve is organized in 25- 45 loosely packed nerve bundles, running mediodorsally in the shaft of the penis. This organization corresponds to that in penes of other mammalian species, but differs from the organization of the other peripheral sensory nerves. Around half of the dorsal penile nerve fibers were myelinated and a human hemi-penis contained a total of 8290 ± 2553 (mean ± SD) axons. Thus, the number of sensory axons in human dorsal penile nerve is higher than in other species described so far. The large fraction of unmyelinated nerve fibers suggesting that conduction speed is not a crucial aspect of penile sensory transmission. |
| License | Creative Commons CC0 1.0 Public Domain Dedication (https://creativecommons.org/publicdomain/zero/1.0/) |
| References |
Citation1 [doi:10.xxx/zzzz] (IsSupplementTo)
Citation2 [arxiv:mmmm.nnnn] (IsSupplementTo) Citation3 [pmid:nnnnnnnn] (IsReferencedBy) |
| Funding |
Exc 2049-390688087
BrainPlay ERC Synergy Grant |
| Keywords |
penis
male nerve fibers sexual behaviour |
| Resource Type |
Dataset |
