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datacite.yml 2.3 KB

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  1. authors:
  2. -
  3. firstname: Bernhard
  4. lastname: Kodritsch
  5. affiliation: 'Helmholtz-Centre for Environmental Research GmbH---UFZ, Permoserstr. 15, 04318 Leipzig, Germany'
  6. -
  7. firstname: Florian
  8. lastname: Schunck
  9. affiliation: 'Osnabrück University, Barbarastr. 12, 49076 Osnabrück, Germany'
  10. id: 'ORCID:0000-0001-7245-953X'
  11. -
  12. firstname: Martin
  13. lastname: Krauss
  14. affiliation: 'Helmholtz-Centre for Environmental Research GmbH---UFZ, Permoserstr. 15, 04318 Leipzig, Germany'
  15. id: 'ORCID:0000-0002-0362-4244'
  16. -
  17. firstname: Andreas
  18. lastname: Focks
  19. affiliation: 'Osnabrück University, Barbarastr. 12, 49076 Osnabrück, Germany'
  20. id: 'ORCID:0000-0002-9031-0808'
  21. -
  22. firstname: Wibke
  23. lastname: Busch
  24. affiliation: 'Helmholtz-Centre for Environmental Research GmbH---UFZ, Permoserstr. 15, 04318 Leipzig, Germany'
  25. id: 'ORCID:0000-0002-5497-6266'
  26. title: 'Survival, nrf2, internal concentration, and external concentration timeseries of zebrafish embryos exposed to Diuron, Diclofenac or Naproxen used in TKTD modelling'
  27. description: 'The dataset contains a number of experiments generated during 2015--2022 at the Helmholtz Centre for Environmental Research---UFZ in Leipzig. The data describe observations of different endpoints measured in zebrafish embryos (ZFE), exposed to the chemicals Diuron, Diclofenac and Naproxen (separately). The observed endpoints were external concentrations, internal body residues in the ZFE, gene expression of *nrf2* (a transcription factor that handles the stress response), and survival. The recommended way to work with this dataset is with the companion code, available under https://github.com/flo-schu/tktd_nrf2_zfe/.'
  28. keywords:
  29. - 'TKTD modelling'
  30. - zebrafish
  31. - nrf2
  32. - 'internal concentration'
  33. - 'gene expression'
  34. - timeseries
  35. - survival
  36. - modelling
  37. license:
  38. name: 'Creative Commons Attribution-ShareAlike 4.0'
  39. url: 'https://creativecommons.org/licenses/by-sa/4.0/deed.en'
  40. funding:
  41. - null
  42. references:
  43. -
  44. id: 'doi:tba'
  45. reftype: IsSupplementTo
  46. citation: 'Schunck F, Kodritsch B, Busch W, Kraus M, Focks A (2024)'
  47. -
  48. id: 'url:https://github.com/flo-schu/tktd_nrf2_zfe'
  49. reftype: IsReferencedBy
  50. citation: 'Analysis of scattered timeseries data from multiple experiments with pymob. Schunck 2024. Github'
  51. resourcetype: Dataset
  52. templateversion: 1.2