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Larissa Höfling ef08c0e364 Funding info update 9 months ago
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datacite.yml ef08c0e364 Funding info update 9 months ago

README.md

CMOS-MEA recordings of mouse retinal ganglion cells upon smooth electrical stimulation

This repository contains data obtained from multi-electrode array recordings of mouse retinal ganglion cells upon smooth electrical stimulation. Both the raw and the preprocessed (spike-sorted) files are available in the respective folders (raw, sorted). You can open and browse the data files using the CMOS-MEA-Tools Software (https://www.multichannelsystems.com/software/cmos-mea-tools, version 2.1.0). This data is described and analysed in the paper Höfling, L., Oesterle, J., Berens, P., & Zeck, G. (2020). Probing and predicting ganglion cell responses to smooth electrical stimulation in healthy and blind mouse retina. Scientific Reports, 10(1), 5248. https://doi.org/10.1038/s41598-020-61899-y.

Navigating the repository

Folder structure is as follows:
(datatype)/(mouse line)/(experimental session)/
where datatype can be raw or sorted (i.e. spike sorted), and mouse line can be wildtype or rd10
Files with filename containing "standard" are recordings upon electrical stimulation;
files with filename containing "spont" are recordings of spontaneous activity;
files with filename containing "470nm" (or similar) are recordings upon light stimulation.

Analysis code

... can be found here: https://github.com/lhoefling/rgc-elstim-modeling/

datacite.yml
Title CMOS-MEA recordings of mouse retinal ganglion cells upon smooth electrical stimulation
Authors Höfling,Larissa;Institute for Ophthalmic Research, University of Tübingen, Germany;ORICD:0000-0003-2459-0706
Zeck,Günther;Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany;ORCID:0000-0003-3998-9883
Description This repository contains data obtained from multi-electrode array recordings of mouse retinal ganglion cells upon smooth electrical stimulation. Both the raw and the preprocessed (spike-sorted) files are available in the respective folders (raw, sorted). You can open and browse the data files using the CMOS-MEA-Tools Software (https://www.multichannelsystems.com/software/cmos-mea-tools, version 2.1.0). This data is described and analysed in the paper Höfling, L., Oesterle, J., Berens, P., & Zeck, G. (2020). Probing and predicting ganglion cell responses to smooth electrical stimulation in healthy and blind mouse retina. Scientific Reports, 10(1), 5248. https://doi.org/10.1038/s41598-020-61899-y
License Creative Commons CC BY-NC-SA (https://creativecommons.org/licenses/by-nc-sa/4.0/)
References Höfling, L., Oesterle, J., Berens, P., & Zeck, G. (2020). Probing and predicting ganglion cell responses to smooth electrical stimulation in healthy and blind mouse retina. Scientific Reports, 10(1), 5248. https://doi.org/10.1038/s41598-020-61899-y [doi:10.1038/s41598-020-61899-y] (IsSupplementTo)
Funding Baden-Württemberg Stiftung, NEU013
DFG, 276693517
DFG, BE5601/4-1
BMBF, 01GQ1601
BMBF, 031L0059A
Keywords neuroscience
electrical stimulation
mouse retina
retinal prosthetics
micro-electrode array recordings
generalized linear models
Resource Type Dataset