Title |
Resolution of subcomponents of EPSCs in rat hair-cell/auditory-nerve fiber synapses |
Authors |
Young,Eric;Johns Hopkins Univ.;ORCID:0000-0003-0334-408X
Wu,Jingjing;Harvard Medical School;ORCID:0000-0001-9625-1661
Niwa,Mamiko;Johns Hopkins Univ.;ORCID0000-0003-1353-3394
Glowatzki,Elisabeth;Johns Hopkins Univ.;ORCID:0000-0003-3135-658X
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Description |
The synapse between inner hair cells and auditory nerve fiber dendrites in rats
shows large EPSCs, which are either monophasic or multiphasic. EPSCs were
deconvolved to allow analysis of individual releases of neurotransmitter.
The results were used to analyze and test models of synaptic release in the hair cell.
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License |
Creative Commons CC0 1.0 Public Domain Dedication (https://creativecommons.org/publicdomain/zero/1.0/)
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References |
Wu JS, Young ED, and Glowatzki E. 2016. Maturation of spontaneous firing properties after hearing onset in rat auditory nerve fibers: Spontaneous rates, refractoriness, and interfiber correlations. J. Neurosci. 36:10584-10597. [doi.org/10.1523/JNEUROSCI.1187-16.2016] (IsSupplementTo)
Young, E.D., Wu, J.J., Niwa, M., and Glowatzki, E. 2020. Resolution of subcomponents of synaptic release from post-synaptic currents in rat hair-cell/ auditory-nerve fiber synapses. BioRχiv 2020.05.13.070920. [doi.org/10.1101/2020.05.13.070920] (IsSupplementTo)
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Funding |
NIDCD, R01DC006476
NIDCD, R01DC012957
NIDCD, P30DC005211
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Keywords |
Synaptic potentials
Deconvolution
Uniquantal
Multiquantal
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Resource Type |
Dataset
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