Stereologic data accompanying the study:
Richard Gaus, Melanie Popal, Helmut Heinsen, Andrea Schmitt, Peter Falkai, Patrick R. Hof, Christoph Schmitz, Alisa Vollhardt (2021) Neuron numbers are decreased in the whole cerebral cortex and in layer V of area 24 in schizophrenia
The repository contains a table (raw_stereology_data.xlsx
) with clinical characteristics and raw stereological estimates of volume, cell counts, and cell densities in the whole cerebral cortex, whole area 24, and layer V of area 24 in the brains of 13 male patients with schizophrenia and 13 age-matched male controls.
Each row in the table represents one separate hemisphere. The table contains the following columns:
| Column | Description | Unit |
| -------- | ----------- | -------- |
| subject
| Subject ID | |
| code
| Subject code | |
| excl
| * | |
| excl_cgm
| * | |
| diagnosis
| Control: 0
, Patient: 1
| |
| hemisphere
| Left or right hemisphere | |
| age
| Age of subject | years |
| pmi
| Post-mortem interval | hours |
| fix
| Fixation time | days |
| cgm_vol
| Volume of whole CGM | cm3 |
| cgm_nn
| Total neuron number in whole CGM | x109 |
| cgm_nd
| Total neuron density in whole CGM | x106 / cm3 |
| area24_vol
| Volume of whole area 24 | cm3 |
| area24_nn
| Total neuron number in whole area 24 | x106 |
| area24_nd
| Total neuron density in whole area 24 | x106 / cm3 |
| area24layer5_vol
| Volume of layer V of area 24 | cm3 |
| area24layer5_nn
| Total neuron number in layer V of area 24 | x106 |
| area24layer5_nd
| Total neuron density in layer V of area 24 | x106 / cm3 |
| ven_number
| VEN number in layer V of area 24 | x103 |
| ven_density
| VEN density in layer V of area 24 | x103 / cm3 |
CGM: cortical gray matter; VEN: von Economo neuron
*All hemispheres where columns excl
/ excl_cgm
carry the value 1
were excluded from the statistical analysis for all outcome variables / only the CGM-related outcome variables due to missing sections.
If you plan to use this data for a publication, please inform us about it and don’t forget to cite the source of the data.