Stereologic data accompanying the study "Neuron numbers are decreased in the whole cerebral cortex and in layer V of area 24 in schizophrenia" by Gaus et al. 2021

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Gaus_etal_2021_Neuron_numbers_decreased_in_schizophrenia

Stereological data accompanying the study:

Richard Gaus, Melanie Popal, Helmut Heinsen, Andrea Schmitt, Peter Falkai, Patrick R. Hof, Christoph Schmitz, Alisa Vollhardt (2021) Neuron numbers are decreased in the whole cerebral cortex and in layer V of area 24 in schizophrenia

The repository contains a table (raw_stereology_data.xlsx) with clinical characteristics and raw stereological estimates from the brains of 13 male patients with schizophrenia and 13 age-matched male controls.

If you plan to use this data for a publication, please inform us about it and don’t forget to cite the source of the data.

Description of data

Each row in the table represents one individual hemisphere. The table contains the following columns:

Column	Description	Unit
`subject`	Subject ID
`code`	Subject code
`excl`	see below*
`excl_cgm`	see below*
`diagnosis`	Control: `0`, Patient: `1`
`hemisphere`	Left or right hemisphere
`age`	Age of subject	years
`pmi`	Post-mortem interval	hours
`fix`	Fixation time	days
`cgm_vol`	Volume of whole CGM	cm³
`cgm_nn`	Total neuron number in whole CGM	x10⁹
`cgm_nd`	Total neuron density in whole CGM	x10⁶ / cm³
`area24_vol`	Volume of whole area 24	cm³
`area24_nn`	Total neuron number in whole area 24	x10⁶
`area24_nd`	Total neuron density in whole area 24	x10⁶ / cm³
`area24layer5_vol`	Volume of layer V of area 24	cm³
`area24layer5_nn`	Total neuron number in layer V of area 24	x10⁶
`area24layer5_nd`	Total neuron density in layer V of area 24	x10⁶ / cm³
`ven_number`	VEN number in layer V of area 24	x10³
`ven_density`	VEN density in layer V of area 24	x10³ / cm³

*All hemispheres where columns excl / excl_cgm carry the value 1 were excluded from the statistical analysis for all outcome variables / only the CGM-related outcome variables (cgm_vol, cgm_nn, cgm_nd) due to missing sections.

CGM: cortical gray matter; VEN: von Economo neuron

datacite.yml
Title	Data set - Neuron numbers are decreased in the whole cerebral cortex and in layer V of area 24 in schizophrenia
Authors	Gaus,Richard;Chair of Neuroanatomy, Institute of Anatomy, Faculty of Medicine, LMU Munich, Munich, Germany;ORCID:0000-0001-5999-0174 Popal,Melanie;Chair of Neuroanatomy, Institute of Anatomy, Faculty of Medicine, LMU Munich, Munich, Germany Heinsen,Helmut;Morphological Brain Research Unit, Department of Psychiatry, University of Würzburg, Würzburg, Germany; Department of Radiology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil;ORCID:0000-0002-4688-4441 Schmitt,Andrea;Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany;ORCID:0000-0002-5426-4023 Falkai,Peter;Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany;ORCID:0000-0003-2873-8667 Hof,Patrick R.;Nash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA;ORCID:0000-0002-3208-1154 Schmitz,Christoph;Chair of Neuroanatomy, Institute of Anatomy, Faculty of Medicine, LMU Munich, Munich, Germany;ORCID:0000-0002-4065-1241 Vollhardt,Alisa;Chair of Neuroanatomy, Institute of Anatomy, Faculty of Medicine, LMU Munich, Munich, Germany
Description	Data set accompanying Gaus et al. (2021) Neuron numbers are decreased in the whole cerebral cortex and in layer V of area 24 in schizophrenia
License	CC BY-SA 4.0 (https://creativecommons.org/licenses/by-sa/4.0/)
References
Funding
Keywords	schizophrenia anterior cingulate area 24 von Economo neurons stereology
Resource Type	Dataset

README.md

Gaus_etal_2021_Neuron_numbers_decreased_in_schizophrenia

Description of data