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doi
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FICN-1320784
másolva summer516658/FICN-1320784
DOI
10.12751/g-node.qdqcp3
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Autism Risk Gene Cul3 Alters Neuronal Morphology via Caspase-3 Activity in Mouse Hippocampal Neurons

Branch: master
Branch-ok Tag-ek
FICN-1320784
Qiangqiang Xia 527f59236b Update 'datacite.yml' 6 hónapja
Figure 1 WB.prism 74b11a89c1 Figure 1 7 hónapja
Figure 2 Sholl and Spine Analysis.prism 80a5bd91c6 Figure 2 7 hónapja
Figure 3 Caspase-3 Activity.prism 6d19a8cef8 Figure 3 7 hónapja
Figure 4 Sholl and Spine Analysis - Caspase-3 Inhibitor.prism 33d65c5132 Figure 4 7 hónapja
Figure 5 PSD95 and vGluT1.prism 74825bd69e Figure 5 7 hónapja
Figure 6 Gehpyrin and vGAT.prism 66b915b4f6 Figure 6 7 hónapja
Figure 7 Inhibitory synapse-Caspase-3 Inhibitor.prism 2d6af0a2fa Figure 7 7 hónapja
Figure S1-Supplementary figure S1.prism d0a39640ce Figure S1 7 hónapja
Graphical Abstract.PNG 2185d91175 Graphical Abstract 7 hónapja
LICENSE 1c28313dc8 Initial commit 1 éve
README.md 036d2582ed Update 'README.md' 7 hónapja
Supplementary information.PDF dc32b82043 Supplementary information 7 hónapja
Supplementary table 1-Detailed Statistics.XLSX ac9b8dd8a2 Supplementary table 1-Detailed Statistics 7 hónapja
datacite.yml 527f59236b Update 'datacite.yml' 6 hónapja

README.md

FICN-1320784

Title: Autism Risk Gene Cul3 Alters Neuronal Morphology via Caspase-3 Activity in Mouse Hippocampal Neurons

Description: This is a original dataset repository for manuscript # 1320784 published at Frontiers in Cellular Neuroscience, including the Western blot (Figure 1 and Figure S1) and immunocytochemistry tests in primary neuronal cultures (Figure 2-8).

The figure files format are .prism, which can be open by Prism GraphPad: https://www.graphpad.com/features; these figure files include the raw data of these Western blots and immunocytochemistry tests at Data tables; statistical analysis at Results; graphs plotted from these raw data at Graphs; figures made from these grpahs at Layouts.

Supplementary material is a .word that can be opened by Office Word, which including the figure legends of Figure S1.

please contact qqxia@uab.edu if you have any further questions on these data.

datacite.yml
Title Autism Risk Gene Cul3 Alters Neuronal Morphology via Caspase-3 Activity in Mouse Hippocampal Neurons
Authors Xia,Qiangqiang;University of Alabama at Birmingham;ORCID:0000-0002-8490-6437
Powell,Criag M.;University of Alabama at Birmingham;ORCID:0000-0001-5451-2165
Description Cul3 regulates the formation or maintenance of cell morphology, GABAergic synaptic puncta, and neuronal viability in developing hippocampal neurons in culture.
License Creative Commons CC0 1.0 Public Domain Dedication (https://creativecommons.org/publicdomain/zero/1.0/)
References Xia Q-q, Singh A, Wang J, Xuan ZX, Singer JD and Powell CM (2024) Autism risk gene Cul3 alters neuronal morphology via caspase-3 activity in mouse hippocampal neurons. Front. Cell. Neurosci. 18:1320784. doi: 10.3389/fncel.2024.1320784 [https://doi.org/10.3389/fncel.2024.1320784] (IsSupplementTo)
Funding National Institute of Mental Health (NIMH), R01 MH113948
Civitan International Research Center, Emerging Scholar Award
Keywords cullin-3
dendrite
axon
spine
synapse
caspase-3
Resource Type Dataset