Jiyun Shin 1924576541 Update 'Figure 3/README.md' | 3 年 前 | |
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Fig. 3A-B.mat | 3 年 前 | |
Fig. 3C.mat | 3 年 前 | |
Fig. 3I&J.mat | 4 年 前 | |
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README.md | 3 年 前 |
Z-scored firing rate of L5 pyramidal neurons in expert and naive rats during the microstimulation task. Normalized by responses during pre-stimulus period [-1 0] s.
Condition | Description |
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Expert | Animals after >3 days of training. |
Naive | Animals without pairing sessions. |
Entry | Description |
---|---|
<cond>_PSTHz |
Z-scores of firing rate responses. |
<cond>_sorted |
Index for sorting cells as in figures. Sorted by mean z-score of [0.2 0.5] s bins. |
binsize |
Binsize for z-scored PSTHs. 50 ms. |
preStim |
Pre-stimulus window. 1 s. |
postStim |
Post-stimulus window. 3 s. |
PSTHs of three distinctive subpopulations of L5 pyramidal neurons in expert rats. [cellNum x binNum] binsize: 100 ms pre-stimulus window: [-2 0] s post-stimulus window: [0 2] s
Condition | Description |
---|---|
ON | Cells with post-stimulus firing rate in [0.3 0.4] s period above mean + 3 x standard deviation (SD). |
OFF | Cells with post-stimulus firing rate in [0.3 0.4] s period below mean - 3 x standard deviation (SD). |
NR | Rest of the cells. |
Entry | Description |
---|---|
<cond>_PSTH |
PSTHs of firing rate responses. |
<cond>_bPSTH |
PSTHs of burst rate responses. |
Motion-corrected peri-stimulus calcium transients (ΔF/F0) of three distinctive subpopulations of L5 apical dendrites in expert mice. Frame rate at 58.62 Hz. Pre-stimulus 1 s and post-stimulus 3.1 s window.
Condition | Description |
---|---|
ON | Dendrites with post-stimulus calcium transients above mean + 3 x standard deviation (SD). |
OFF | Dendrites with post-stimulus calcium transients below mean - 3 x standard deviation (SD). |
NR | Rest of the dendrites. |
Field | Description |
---|---|
avgTrace |
Average peri-stimulus calcium traces (ΔF/F0) for each dendrite. |
Effects of optogenetic and pharmacological manipulations of dendritic activity on learning of the microstimulation detection task.
Condition | Description |
---|---|
Ctrl | Animals after pairing sessions. No virus expression, but CNO was injected into L1 of S1. |
BacL1 | Animals after pairing sessions. GABAb receptor agonist baclofen was applied to L1 of S1. |
SST | SST-cre x ChR2 mice after pairing sessions. Somatostatin-positive interneurons were optogenetically activated by LED illumination on the surface of S1. |
Entry | Description |
---|---|
<cond>_cumvals |
The cumulative learning curve statistics for the condition. Values on row N (N=1, ... 100) represents the cumulative learning score of each animal after N trials. |
<cond> |
The normalized learning scores for each animal belonging to the condition. |
datacite.yml | |
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Title | Perirhinal input to neocortical layer 1 controls learning |
Authors |
Doron,Guy;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: 0000-0003-1252-5747
Shin,Jiyun N.;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: 0000-0002-0534-6938 Takahashi,Naoya;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: 0000-0002-6008-4627 Drüke,Moritz;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: 0000-0002-6787-9377 Bocklisch,Christina;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: Skenderi,Salina;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: 0000-0003-4779-4541 de Mont,Lisa;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: 0000-0003-3829-0712 Toumazou,Maria;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: Ledderose,Julia;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: 0000-0001-5458-6287 Brecht,Michael;Institut für Biologie, House 6, Philippstr. 13, Humboldt Universität, Berlin, 10115 Germany.;ORCID: 0000-0002-5387-0953 Naud,Richard;uOttawa Brain and Mind Institute, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, K1H 8M5, Canada.;ORCID: 0000-0001-7383-3095 Larkum,Matthew E.;Institut für Biologie, Neurocure Center for Excellence, Chariteplatz 1 / Virchowweg 6, Charité Universitätsmedizin Berlin & Humboldt Universität, Berlin, 10117 Germany.;ORCID: 0000-0001-9799-2656 |
Description | Example description that can contain linebreaks but has to maintain indentation. |
License | Creative Commons Attribution 4.0 International Public License (https://creativecommons.org/licenses/by/4.0/) |
References |
PublicationName1 [doi:10.xxx/zzzz] (IsSupplementTo)
PublicationName2 [arxiv:mmmm.nnnn] (IsSupplementTo) PublicationName3 [pmid:nnnnnnnn] (IsReferencedBy) |
Funding |
DFG, EXC 257 NeuroCure
DFG, DFG.327654276 (SFB 1315) EU, EU.785907 (HBP SGA2) EU, EU.670118 (Active Cortex) NSERC, Discovery grant CIHR, Project grant |
Keywords |
Neuroscience
Electrophysiology Behavior Learning and memory Neocortex Dendrites L5 pyramidal neuron Perirhinal cortex Layer 1 |
Resource Type |
Dataset |