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@@ -2,47 +2,48 @@
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## Fig. 1C.mat
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-Calcium responses(?) of dendrites(?) of S1 layer 5 neurons to microstimulation(?) before and after pairing(?). Representative session from an animal(?). 5-sec recording at 30 Hz, and stimulation occurred at 2 seconds.
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+Calcium responses of perirhinal axons in layer 1 of S1 to microstimulation before and after the first training session. Pooled trials from all animals (n=3). 5-sec recording at 30 Hz, and stimulation occurred at 2 seconds.
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-| Entry | Description |
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-| ----------- | ---------------------------------------------------- |
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-| `prePSTCa` | Baseline-subtracted ∆F/F responses before pairing(?) |
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-| `postPSTCa` | Baseline-subtracted ∆F/F responses after pairing(?) |
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+| Entry | Description |
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+| ------------- | ---------------------------------------------------- |
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+| `prePSTCa` | Baseline-subtracted ∆F/F responses before the training |
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+| `postPSTCa` | Baseline-subtracted ∆F/F responses after the training |
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+| `rewardPSTCa` | Baseline-subtracted ∆F/F responses to reward alone |
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## Fig. 1E.mat
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-Calcium responses(?) of dendrites(?) to microstimulation(?) before and after pharmacogenetic inhibition of PRh inputs in L1 of S1. The baseline-subtracted ∆F/F responses during the 1-second period after stimulation was averaged for each trunk. Average values for individual animals are deposited.
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+Excitatory postsynaptic currents (EPSCs) of S1 neurons in response to optogenetic activation of perirhinal axons in layer 1 of S1. See Fig. S4 for individual cell responses.
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-| Entry | Description |
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-| --------- | ---------------------------------------- |
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-| `preCNO` | Average responses before CNO application |
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-| `postCNO` | Average responses after CNO application |
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+| Entry | Description |
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+| --------- | ---------------------------- |
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+| `preCNO` | EPSCs before CNO application |
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+| `postCNO` | EPSCs after CNO application |
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## Fig.1F
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-Distribution of PRh projection in S1. Normalized signal distribution was measured along the neocortical thickness.
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+Distribution of PRh projection in S1. Normalized signal distribution was measured along the neocortical depths.
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-For each file, the entry `*Depth` represents the binning borders in terms of the normalized depth along the full thickness of the neocortex. The entry `norm_*` contains the normalized signals in the bins, where each column corresponds to the data from an animal(?).
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+For each file, the entry `*Depth` represents the binned absolute depths of the neocortex. The entry `norm_*` contains the normalized signals in the bins, where each column corresponds to the data from a brain section.
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### Files
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-| File name | Description |
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-| --------------- | -------------------------------------------------- |
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-| ChicagoBlue.mat | ChicagoBlue was injected into PRh of mice. |
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-| MouseYFP.mat | YFP-expressing rAAV was injected into PRh of mice. |
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-| RatYFP.mat | YFP-expressing rAAV was injected into PRh of rats. |
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+| File name | Description |
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+| --------------- | --------------------------------------------------------------------------- |
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+| ChicagoBlue.mat | Intensity of ChicagoBlue in S1 after injection in mouse S1. |
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+| MouseYFP.mat | Intensity of YFP (axon terminals) after injection of rAAV was in mouse PRh. |
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+| RatYFP.mat | Intensity of YFP (axon terminals) after injection of rAAV was in rat PRh. |
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## Fig. 1G&H.mat
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-Effects of pharmacogenetic inhibition of PRh inputs in L1 of S1 on learning of an animal.
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+Effects of DREADD inhibition of PRh inputs to L1 of S1 on learning of the microstimulation detection task.
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### Conditions
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| Condition | Description |
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| -------------- | ------------------------------------------------------------ |
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| Untrained | Animals without any prior experience of pairing. No virus was expressed. No drug injection was performed. |
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-| Ctrl | Animals after several pairings. Virus was expressed in PRh, but no drug injection was performed (or vehicle was injected?). |
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-| Dreadd | Animals after several pairings. Virus was expressed in PRh, and CNO was injected into L1 of S1 before testing of the learning. |
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+| Ctrl | Animals after pairing sessions. No virus expression, but CNO was injected into L1 of S1. |
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+| Dreadd | Animals after pairing sessions. Virus was expressed in PRh, and CNO was injected into L1 of S1 before testing of the learning. |
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| Expert_preCNO | Animals being fully trained with the task. Virus was expressed in PRh. Data was obtained before injection of CNO into L1 of S1. |
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| Expert_postCNO | Animals being fully trained with the task. Virus was expressed in PRh. Data was obtained after injection of CNO into L1 of S1. |
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