Data and code from our 2020 manuscript on reward prediction error signaling in ventral pallidum.

David Ottenheimer adc662d20a Update 'README.md' 4 years ago
Data dd28f08735 Upload remaining data 4 years ago
MatlabScripts 46c0d9df5b Update ottBari2020_root.m 4 years ago
LICENSE 13930a9fbc Initial commit 4 years ago
README.md adc662d20a Update 'README.md' 4 years ago
datacite.yml 802e8f1977 Update 'datacite.yml' 4 years ago

README.md

VP_RPE_2020

Data and analysis for our 2020 manuscript "A quantitative reward prediction error signal in ventral pallidum" in Nature Neuroscience. An earlier version of the manuscript is available on bioRxiv: https://doi.org/10.1101/807842

All of the preprocessed data is available in the “Data" folder. There you can also find Matlab data files created with scripts in the MatlabScripts folders “1_InitialAnalysis” and “2_Modeling”. Note you have to download the .zip files in the Data folder individually.

You can generate most of the figures in the paper by downloading the Data folder and the MatlabScripts folder, adding both folders to your Matlab path, and running the scripts in the MatlabScripts folder “3_Figures” — particularly “MainFigures.m”, as well as the scripts in “AdditionalFigures.”

If you get error messages, they're likely related to pathname. You'll want to change the pathname in "MatlabScripts/HelperFunctions/ottBari2020_root.m" to the folder that contains the Data folder as well as the pathname for the behavior files for the "opto" AdditionalFigures scripts.

There's an associated GitHub: https://github.com/djottenheimer/VP_RPE_2020

datacite.yml
Title Analysis of a reward prediction error signal in ventral pallidum
Authors Ottenheimer,David J.;Johns Hopkins University;ORCID:0000-0003-4882-1898
Bari,Bilal A.;Johns Hopkins University;ORCID:0000-0002-8381-3802
Sutlief,Elissa;Johns Hopkins University;ORCID:0000-0001-5174-9060
Fraser,Kurt M.;Johns Hopkins University;ORCID:0000-0002-2988-7683
Kim,Tabitha H.;Johns Hopkins University
Richard,Jocelyn M.;University of Minnesota;ORCID:0000-0001-5750-0418
Cohen,Jeremiah Y.;Johns Hopkins University
Janak,Patricia H.;Johns Hopkins University;ORCID:0000-0002-3333-9049
Description This data and code accompanies our manuscript "A quantitative reward prediction error in ventral pallidum" which will be published in Nature Neuroscience and an earlier version of which is available on bioRxiv. It contains single unit, extracellular electrophysiological data from nucleus accumbens and ventral pallidum in rats performing reward-seeking tasks for sucrose, maltodextrin, and water. The analysis here focuses on the outcome-evoked signaling and uses an outcome-history based modeling approach to characterize reward prediction error signaling in individual neurons.
License Creative Commons CC0 1.0 Public Domain Dedication (https://creativecommons.org/publicdomain/zero/1.0/)
References Ottenheimer, David J., Bilal A. Bari, Elissa Sutlief, Kurt M. Fraser, Tabitha H. Kim, Jocelyn M. Richard, Jeremiah Y. Cohen, and Patricia H. Janak. 'A history-derived reward prediction error signal in ventral pallidum.' bioRxiv (2019): 807842. [doi:10.1101/807842] (IsSupplementTo)
Ottenheimer, David J., Bilal A. Bari, Elissa Sutlief, Kurt M. Fraser, Tabitha H. Kim, Jocelyn M. Richard, Jeremiah Y. Cohen, and Patricia H. Janak. 'A history-derived reward prediction error signal in ventral pallidum.' Nature Neuroscience (2020). [] (IsSupplementTo)
Funding NIH, 5T32NS91018-17
NIH, F30MH110084
NIH, K99AA025384
NIH, R01DA042038
NIH, R01NS104834
NIH, R01DA035943
NSF, DGE1746891
Keywords Neuroscience
Electrophysiology
Single unit
Ventral pallidum
Nucleus accumbens
Reinforcement learning
Modeling
Dopamine
Basal Ganglia
Reward
Resource Type Dataset