We use cookies to ensure you get the best experience on our website
Home Explore Help News
Register Sign In
Kostyalikd
/
VD-EEG
DOI
10.12751/g-node.03o44d
1
0
Fork 1
Files Issues 0 Pull Requests 0 Wiki

Behaviour and EEG recorded during the touchscreen Visual Disrimination task performance in rats

Branch: master
Branches Tags
VD-EEG
Diana Kostyalik e4a80eaa02 Frissítés "datacite.yml" 2 years ago
Behavioural data 335ca3d7f2 Fájlok feltöltése 'Behavioural data' 2 years ago
ERSP data_MK-801 6712ef6378 Fájlok feltöltése 'ERSP data_MK-801' 2 years ago
ERSP data_Scopolamine 21d7bac9bf Fájlok feltöltése 'ERSP data_Scopolamine' 2 years ago
MK-801_EEG fd35e68e53 Fájlok feltöltése 'MK-801_EEG' 2 years ago
Scopolamine_EEG 594e1b1c78 Fájlok feltöltése 'Scopolamine_EEG' 2 years ago
preprocessed data_MK-801 35574a5afa Fájlok feltöltése 'preprocessed data_MK-801' 2 years ago
preprocessed data_Scopolamine 31590827ba Fájlok feltöltése 'preprocessed data_Scopolamine' 2 years ago
LICENSE 4adf2d015c Initial commit 2 years ago
README.md 3ac38dc36c Frissítés "README.md" 2 years ago
datacite.yml e4a80eaa02 Frissítés "datacite.yml" 2 years ago

README.md

VD-EEG

Behaviour and EEG recorded during the touchscreen Visual Disrimination task performance in rats.

.smr files contain raw EEG data of rats' epidural EEG recordings. Subjects were marked with _S001-S012 in the .smr file names.

Electrode channel numbers

  1. VISUAL (OCCIPITAL) LEFT (VL)
  2. VISUAL (OCCIPITAL) RIGHT (VR)
  3. PARIETAL LEFT (PL)
  4. PARIETAL RIGHT (PR)
  5. "-"
  6. "-"
  7. FRONTAL LEFT (FL)
  8. FRONTAL RIGHT (FR)

Bad Channels in each rat: 5, 6 (no electrode was implanted)

samplingRate = 10000;

triggers: channel 12- correct touch channel 13- incorrect touch channel 14- image displayed channel 15- tray entry

Data preprocessing:

High Pass Filter: 1 Hz Low Pass Filter: 80 Hz Notch: 45-55 Hz ReSampling: 1000 Hz Artefact selection by ICA and visual inspection Epoching: -1.5 +1.5 sec (t=0: correct touch) Baseline: -1 -0.7 sec Data were re-referenced to the average

datacite.yml
Title Response-related sensorimotor rhythms under scopolamine and MK-801 exposures in the touchscreen Visual Discrimination test in rats
Authors Kostyalik,Diana;Cognitive Pharmacology Laboratory, Department of Pharmacology and Drug Safety, Gedeon Richter Plc;ORCID:0000-0003-3552-4528
Kelemen,Kristóf;Cognitive Pharmacology Laboratory, Department of Pharmacology and Drug Safety, Gedeon Richter Plc;ORCID:0000-0001-7378-0843
Lendvai,Balázs ;Department of Pharmacology and Drug Safety,Gedeon Richter Plc;ORCID:0000-0001-9289-4715
Hernádi,István;Department of Pharmacology and Drug Safety,Gedeon Richter Plc;ORCID:0000-0001-7882-4817
Román,Viktor;Department of Pharmacology and Drug Safety,Gedeon Richter Plc;ORCID:0000-0002-4849-3591
Lévay,György;Department of Pharmacology and Drug Safety,Gedeon Richter Plc;ORCID:0000-0002-5865-6462
Description The human mu rhythm has been suggested to represent an important function in information processing. Rodent homologue rhythms have been assumed though no study has investigated them from the cognitive aspect yet. As voluntary goal-directed movements induce the desynchronization of mu rhythm, we aimed at exploring whether the touch-response-related brain activity during the touchscreen visual discrimination (VD) task is suitable to detect sensorimotor rhythms in healthy and cognitively impaired rats. Different doses of scopolamine or MK-801 were injected subcutaneously to male Lister Hooded rats, and epidural electroencephalography (EEG) was recorded during task performance. Arciform ~10 Hz oscillations appeared during visual processing, then two characteristic alpha/beta desynchronization-resynchronization patterns emerged predominating above the sensorimotor areas, serving different motor functions. Beyond causing cognitive impairment, both drugs supressed the touch-related upper alpha (10-15 Hz) reactivity for desynchronization. Reaction time positively correlated with movement-related alpha and beta power both in normal and impaired conditions. These results support the existence of a mu homologue rodent rhythm whose upper alpha component appeared to be modulated by cholinergic and glutamatergic mechanisms and its power change might indicate a potential EEG correlate of processing speed. The VD task can be utilized for the investigation of sensorimotor rhythms in rats.
License Creative Commons CC0 1.0 Public Domain Dedication (https://creativecommons.org/publicdomain/zero/1.0/)
References
Funding Gedeon Richter Plc.
Hungarian governmental grant, 2017-1.2.1-NKP-2017-00002
Keywords Neuroscience
Visual Discrimination
EEG
Scopolamine
MK-801
Resource Type Dataset