Goff-et-al-2023

Goff-et-al-2023

This is the accompanying source dataset and associated original code to the manuscript published in Cell Reports 2023: VIP interneuron impairment promotes in vivo circuit dysfunction and autism-related behaviors in Dravet syndrome. Kevin M. Goff, Sophie R. Liebergall, Evan Jiang, Ala Somarowthu, and Ethan M. Goldberg

Preprocessed 2P imaging data provided in .mat file format for analysis in Matlab (2021a or newer). The function MI_values.m produces the modulation index values that we report in the paper and form the basis of our conclusions.

Additional files for analysis are provided with the preprocessed data to generate the main panels from each figure. Each figure has one associated zip file that includes both a script and the data required to generate each figure.

Any additional analysis from supplemental figures available upon request from the coresponding author.

Many figures are generated with gramm for Matlab (doi: 10.21105/joss.00568) which will need to be added to the matlab path prior to running the scripts