123456789101112131415161718192021222324252627282930313233343536373839404142434445464748495051525354555657585960616263646566676869707172737475767778798081828384858687888990919293949596979899100101 |
- # Metadata for DOI registration according to DataCite Metadata Schema 4.1.
- # For detailed schema description see https://doi.org/10.5438/0014
- ## Required fields
- # The main researchers involved. Include digital identifier (e.g., ORCID)
- # if possible, including the prefix to indicate its type.
- authors:
- -
- firstname: "Ryszard"
- lastname: "Auksztulewicz"
- affiliation: "Center for Cognitive Neuroscience Berlin, Free University Berlin, Berlin, Germany"
- -
- firstname: "Vani"
- lastname: "Rajendran"
- affiliation: "Dept of Neuroscience, City University of Hong Kong, Hong Kong S.A.R."
- -
- firstname: "Fei"
- lastname: "Peng"
- affiliation: "Dept of Neuroscience, City University of Hong Kong, Hong Kong S.A.R."
- -
- firstname: "Jan"
- lastname: "Schnupp"
- affiliation: "Dept of Neuroscience, City University of Hong Kong, Hong Kong S.A.R."
- -
- firstname: "Nicol"
- lastname: "Harper"
- affiliation: "Dept of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK"
- # A title to describe the published resource.
- title: "Omission responses in local field potentials in rat auditory cortex"
- # Additional information about the resource, e.g., a brief abstract.
- description: |
- Non-invasive recordings of gross neural activity in humans often show responses
- to omitted stimuli in steady trains of identical stimuli. This has been taken
- as evidence for the neural coding of prediction or prediction error. However,
- evidence for such omission responses from invasive recordings of cellular-scale
- responses in animal models is scarce. Here, we sought to characterise omission
- responses using extracellular recordings in the auditory cortex of anaesthetised
- rats. We profiled omission responses across local field potentials (LFP), analogue
- multiunit activity (AMUA), and single/multi-unit spiking activity, using stimuli
- that were fixed-rate trains of acoustic noise bursts where 5% of bursts were randomly
- omitted. Significant omission responses were observed in LFP and AMUA signals, but
- not in spiking activity. These omission responses had a lower amplitude and longer
- latency than burst-evoked sensory responses, and omission response amplitude increased
- as a function of the number of preceding bursts. Together, our findings show that
- omission responses are most robustly observed in LFP and AMUA signals (relative to
- spiking activity) but do not show evidence for low-frequency phase locking. This has
- implications for models of cortical processing that require many neurons to encode
- prediction error in their spike output.
- # Lit of keywords the resource should be associated with.
- # Give as many keywords as possible, to make the resource findable.
- keywords:
- - Neuroscience
- - Auditory Cortex
- - Rat
- - Omission response
- - Predictive processing
- # License information for this resource. Please provide the license name and/or a link to the license.
- # Please add also a corresponding LICENSE file to the repository.
- license:
- name: "Creative Commons CC0 1.0 Public Domain Dedication"
- url: "https://creativecommons.org/publicdomain/zero/1.0/"
- ## Optional Fields
- # Funding information for this resource.
- # Separate funder name and grant number by comma.
- funding:
- - "European Commission; 750459"
- - "Hong Kong General Research Fund; 11100518"
- - "European Community/Hong Kong Research Grants Council Joint Research Scheme; 9051402"
- - "Wellcome Trust; WT09975MA"
- - "Wellcome Trust; WT108369/2015/Z"
- # Related publications. reftype might be: IsSupplementTo, IsDescribedBy, IsReferencedBy.
- # Please provide digital identifier (e.g., DOI) if possible.
- # Add a prefix to the ID, separated by a colon, to indicate the source.
- # Supported sources are: DOI, arXiv, PMID
- # In the citation field, please provide the full reference, including title, authors, journal etc.
- references:
- -
- id: "doi:10.1101/2022.02.11.479668"
- reftype: "IsSupplementTo"
- citation: "Omission responses in field potentials but not spikes in rat auditory cortex. Ryszard Auksztulewicz, Vani Gurusamy Rajendran, Fei Peng, Jan Wilbert Hendrik Schnupp, Nicol Spencer Harper. bioRxiv 2022.02.11.479668; doi: https://doi.org/10.1101/2022.02.11.479668"
- -
- id: "doi:tba"
- reftype: "IsSupplementTo"
- citation: "Omission responses in local field potentials in rat auditory cortex. Ryszard Auksztulewicz, Vani Gurusamy Rajendran, Fei Peng, Jan Wilbert Hendrik Schnupp, Nicol Spencer Harper. BMC Biology (in press)"
- # Resource type. Default is Dataset, other possible values are Software, DataPaper, Image, Text.
- resourcetype: Dataset
- # Do not edit or remove the following line
- templateversion: 1.2
|