pupil_timescales_dLGN/datacite.yml

# Metadata for DOI registration according to DataCite Metadata Schema 4.1.
# For detailed schema description see https://doi.org/10.5438/0014

## Required fields

# The main researchers involved. Include digital identifier (e.g., ORCID)
# if possible, including the prefix to indicate its type.
authors:
  -
    firstname: "Davide"
    lastname: "Crombie"
    affiliation: "LMU Munich"
    id: "ORCID:0000-0003-3424-3249"
  -
    firstname: "Martin"
    lastname: "Spacek"
    affiliation: "LMU Munich"
    id: "ORCID:0000-0002-9519-3284"
  -
    firstname: "Christian"
    lastname: "Leibold"
    affiliation: "Albert-Ludwigs-Universität Freiburg"
    id: "ORCID:0000-0002-4859-8000"
  -
    firstname: "Laura"
    lastname: "Busse"
    affiliation: "LMU Munich"
    id: "ORCID:0000-0002-6127-7754"

# A title to describe the published resource.
title: "Spiking activity in the visual thalamus is coupled to pupil dynamics across temporal scales"

# Additional information about the resource, e.g., a brief abstract.
description: |
	The processing of sensory information, even at early stages, is influenced by the internal state
    of the animal. Internal states, such as arousal, are often characterized by relating neural activity 
    to a single “level” of arousal, defined by a behavioral indicator such as pupil size. In this study, 
    we expand the understanding of arousal-related modulations in sensory systems by uncovering multiple 
    timescales of pupil dynamics and their relationship to neural activity. Specifically, we observed a 
    robust coupling between spiking activity in the mouse dorsolateral geniculate nucleus (dLGN) of the 
    thalamus and pupil dynamics across timescales spanning a few seconds to several minutes. Throughout all
    these timescales, two distinct spiking modes – individual tonic spikes and tightly clustered bursts of
    spikes – preferred opposite phases of pupil dynamics. This multi-scale coupling reveals modulations 
    distinct from those captured by pupil size per se, locomotion, and eye movements. Furthermore, coupling
    persisted even during viewing of a naturalistic movie, where it contributed to differences in the 
    encoding of visual information. We conclude that dLGN spiking activity is under the simultaneous 
    influence of multiple arousal-related processes associated with pupil dynamics occurring over a 
    broad range of timescales.

# Lit of keywords the resource should be associated with.
# Give as many keywords as possible, to make the resource findable.
keywords:
  - Neuroscience
  - Vision
  - Thalamus
  - EMD
  - Pupil
  - Arousal
  - Timescales

# License information for this resource. Please provide the license name and/or a link to the license.
# Please add also a corresponding LICENSE file to the repository.
license:
  name: "Creative Commons Attribution 4.0 International Public License"
  url: "https://creativecommons.org/licenses/by/4.0/"



## Optional Fields

# Funding information for this resource.
# Separate funder name and grant number by comma.
funding:
  - "DFG, RTG 2175 “Perception in context and its neural basis”
  - "DFG, SFB 1233 TP 13, project number 276693517"
  - "DFG, SFB 870 TP 19, project number 118803580"
  - "LMU Munich, TU Munich and the Bavarian Ministry for Science and Art, ONE Munich Strategy Forum grant"
  - "Volkswagen Foundation, SmartStart program of the Bernstein Network for Computational Neuroscience"


# Related publications. reftype might be: IsSupplementTo, IsDescribedBy, IsReferencedBy.
# Please provide digital identifier (e.g., DOI) if possible.
# Add a prefix to the ID, separated by a colon, to indicate the source.
# Supported sources are: DOI, arXiv, PMID
# In the citation field, please provide the full reference, including title, authors, journal etc.
references:
  -
    id: "doi:10.xxx/zzzz"
    reftype: "IsSupplementTo"
    citation: "Crombie, D., Spacek, M.A., Leibold, C., Busse, L., 202x. Spiking activity in the visual thalamus is coupled to pupil dynamics across temporal scales"

# Resource type. Default is Dataset, other possible values are Software, DataPaper, Image, Text.
resourcetype: Dataset

# Do not edit or remove the following line
templateversion: 1.2