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+# Metadata for DOI registration according to DataCite Metadata Schema 4.1.
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+# For detailed schema description see https://doi.org/10.5438/0014
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+
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+## Required fields
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+
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+# The main researchers involved. Include digital identifier (e.g., ORCID)
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+# if possible, including the prefix to indicate its type.
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+authors:
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+ -
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+ firstname: "Davide"
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+ lastname: "Crombie"
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+ affiliation: "LMU Munich"
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+ id: "ORCID:0000-0003-3424-3249"
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+ -
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+ firstname: "Martin"
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+ lastname: "Spacek"
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+ affiliation: "LMU Munich"
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+ id: "ORCID:0000-0002-9519-3284"
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+ -
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+ firstname: "Christian"
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+ lastname: "Leibold"
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+ affiliation: "Albert-Ludwigs-Universität Freiburg"
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+ id: "ORCID:0000-0002-4859-8000"
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+ -
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+ firstname: "Laura"
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+ lastname: "Busse"
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+ affiliation: "LMU Munich"
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+ id: "ORCID:0000-0002-6127-7754"
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+
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+# A title to describe the published resource.
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+title: "Spiking activity in the visual thalamus is coupled to pupil dynamics across temporal scales"
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+
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+# Additional information about the resource, e.g., a brief abstract.
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+description: |
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+ The processing of sensory information, even at early stages, is influenced by the internal state
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+ of the animal. Internal states, such as arousal, are often characterized by relating neural activity
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+ to a single “level” of arousal, defined by a behavioral indicator such as pupil size. In this study,
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+ we expand the understanding of arousal-related modulations in sensory systems by uncovering multiple
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+ timescales of pupil dynamics and their relationship to neural activity. Specifically, we observed a
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+ robust coupling between spiking activity in the mouse dorsolateral geniculate nucleus (dLGN) of the
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+ thalamus and pupil dynamics across timescales spanning a few seconds to several minutes. Throughout all
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+ these timescales, two distinct spiking modes – individual tonic spikes and tightly clustered bursts of
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+ spikes – preferred opposite phases of pupil dynamics. This multi-scale coupling reveals modulations
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+ distinct from those captured by pupil size per se, locomotion, and eye movements. Furthermore, coupling
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+ persisted even during viewing of a naturalistic movie, where it contributed to differences in the
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+ encoding of visual information. We conclude that dLGN spiking activity is under the simultaneous
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+ influence of multiple arousal-related processes associated with pupil dynamics occurring over a
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+ broad range of timescales.
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+
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+# Lit of keywords the resource should be associated with.
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+# Give as many keywords as possible, to make the resource findable.
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+keywords:
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+ - Neuroscience
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+ - Vision
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+ - Thalamus
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+ - EMD
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+ - Pupil
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+ - Arousal
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+ - Timescales
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+
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+# License information for this resource. Please provide the license name and/or a link to the license.
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+# Please add also a corresponding LICENSE file to the repository.
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+license:
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+ name: "Creative Commons Attribution 4.0 International Public License"
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+ url: "https://creativecommons.org/licenses/by/4.0/"
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+
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+
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+
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+## Optional Fields
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+
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+# Funding information for this resource.
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+# Separate funder name and grant number by comma.
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+funding:
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+ - "DFG, RTG 2175 “Perception in context and its neural basis”
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+ - "DFG, SFB 1233 TP 13, project number 276693517"
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+ - "DFG, SFB 870 TP 19, project number 118803580"
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+ - "LMU Munich, TU Munich and the Bavarian Ministry for Science and Art, ONE Munich Strategy Forum grant"
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+ - "Volkswagen Foundation, SmartStart program of the Bernstein Network for Computational Neuroscience"
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+
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+
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+# Related publications. reftype might be: IsSupplementTo, IsDescribedBy, IsReferencedBy.
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+# Please provide digital identifier (e.g., DOI) if possible.
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+# Add a prefix to the ID, separated by a colon, to indicate the source.
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+# Supported sources are: DOI, arXiv, PMID
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+# In the citation field, please provide the full reference, including title, authors, journal etc.
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+references:
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+ -
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+ id: "doi:10.xxx/zzzz"
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+ reftype: "IsSupplementTo"
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+ citation: "Crombie, D., Spacek, M.A., Leibold, C., Busse, L., 202x. Spiking activity in the visual thalamus is coupled to pupil dynamics across temporal scales"
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+
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+# Resource type. Default is Dataset, other possible values are Software, DataPaper, Image, Text.
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+resourcetype: Dataset
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+
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+# Do not edit or remove the following line
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+templateversion: 1.2
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