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Paul Pfeiffer 5 tahun lalu
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+# Functional aspects of interneuron morphology in the subiculum
+
+Interneurons in the subiculum  have a polar axonal cloud instead of a circular as found in other brain regions. Additionally, pyramidal neurons in the subiculum lack recurrent connections, but they connect via recurrent inhibition. Therefore, inhibition plays a major role in this circuitry and we pose the question, which function the extraordinary axon morphology serves in this setting.
+
+## Model
+
+1. Distribute excitatory somata in space.
+2. Distribute inhibitory somata in space.
+3. Choose an axonal shape (polar or circular).
+3. Connect excitatory neurons which are contained the same interneuron axonal cloud.
+
+
+## Analysis
+
+1. Compare first and second order connectivity
+
+Two neurons directly connected neuron inhibit each other, because they project to the same interneuron (as a circuit motif E<->I<->E). Therefore, second order neighbors are effectively excitatory (via disinhibition). We therefore extracted the distance dependent first and second order connectivity to compare them for polar and circular axonal shapes.
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