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- authors:
- -
- firstname: 'Ricardo'
- lastname: 'Kienitz'
- affiliation: 'Ernst Strüngmann Institute (ESI) for Neuroscience in Cooperation with Max Planck Society, Deutschordenstraße 46, 60528 Frankfurt a. M., Germany; Institute of Neuroscience, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK; Epilepsy Center Frankfurt Rhine-Main, Center of Neurology and Neurosurgery, Goethe University, Schleusenweg 2-16, 60528 Frankfurt a.M., Germany'
- -
- firstname: 'Michele A'
- lastname: 'Cox'
- affiliation: 'Department of Psychology, Vanderbilt University, 111 21st Avenue South, 301 Wilson Hall, Nashville, TN 37240, USA; Department of Brain and Cognitive Sciences - University of Rochester, Meliora Hall, University of Rochester, Rochester, NY 14627'
- -
- firstname: 'Kacie'
- lastname: 'Dougherty'
- affiliation: 'Department of Psychology, Vanderbilt University, 111 21st Avenue South, 301 Wilson Hall, Nashville, TN 37240, USA; Princeton Neuroscience Institute, Princeton University, Washington Rd, Princeton, New Jersey 08544, USA'
- -
- firstname: 'Richard C'
- lastname: 'Saunders'
- affiliation: 'Laboratory of Neuropsychology, NIMH, Convent Drive 49, Bethesda, MD 20892, USA'
- -
- firstname: 'Joscha T'
- lastname: 'Schmiedt'
- affiliation: 'Ernst Strüngmann Institute (ESI) for Neuroscience in Cooperation with Max Planck Society, Deutschordenstraße 46, 60528 Frankfurt a. M., Germany'
- -
- firstname: 'David A'
- lastname: 'Leopold'
- affiliation: 'Laboratory of Neuropsychology, NIMH, Convent Drive 49, Bethesda, MD 20892, USA; Neurophysiology Imaging Facility, NIMH, NINDS & NEI, 49 Convent Drive, Bethesda, MD 20892, USA'
- -
- firstname: 'Alexander'
- lastname: 'Maier'
- affiliation: 'Department of Psychology, Vanderbilt University, 111 21st Avenue South, 301 Wilson Hall, Nashville, TN 37240, USA'
- -
- firstname: 'Michael C'
- lastname: 'Schmid'
- affiliation: 'Institute of Neuroscience, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK; Faculty of Science and Medicine, Chemin du Musée 5, 1700 Fribourg, Switzerland'
- title: 'Data from: Theta but not gamma oscillations in area V4 depend on input from primary visual cortex'
- description: 'Theta (3-9 Hz) and gamma (30-100 Hz) oscillations have been observed at different levels along the hierarchy of cortical areas and across a wide set of cognitive tasks. In the visual system, the emergence of both rhythms in primary visual cortex (V1) and mid-level cortical areas V4 have been linked with variations in perceptual reaction times [1–5]. Based on analytical methods to infer causality in neural activation patterns, it was concluded that gamma and theta oscillations might both reflect feedforward sensory processing from V1 to V4 [6–10]. Here we report on experiments in macaque monkeys in which we experimentally assessed the presence of both oscillations in the neural activity recorded from multi-electrode arrays in V1 and V4 before and after a permanent V1-lesion. With intact cortex theta and gamma oscillations could be reliably elicited in V1 and V4 when monkeys viewed a visual contour illusion and showed phase-to- amplitude coupling. Laminar analysis in V1 revealed that both theta and gamma oscillations occurred primarily in the supragranular layers, the cortical output compartment of V1. However, there was a clear dissociation between the two rhythms in V4 that became apparent when the major feedforward input to V4 was removed by lesioning V1: While V1 lesioning eliminated V4 theta, it had little effect on V4 gamma power except for delaying its emergence by >100 ms. These findings suggest that theta is more tightly associated with feedforward processing than gamma and pose limits on the proposed role of gamma as a feedforward mechanism.'
- keywords:
- - 'neuroscience'
- - 'visual cortex'
- - 'primary visual cortex (V1)'
- - 'V4'
- - 'oscillations'
- - 'rhythms'
- - 'theta'
- - 'gamma'
- - 'lesion'
- - 'feedforward'
- - 'feedback'
- license:
- name: 'CC BY-NC-SA 4.0'
- url: 'https://creativecommons.org/licenses/by-nc-sa/4.0/'
- funding:
- - 'National Institute of Mental Health Grant ZIA-MH002838 to D.A.L.'
- - 'National Eye Institute Training Grant (2T32 EY007135-21) to K.D.'
- - 'Alfred P. Sloan Fellowship to A.M.'
- - 'Research Grant by the Whitehall Foundation to A.M.'
- - 'Career Starter Grant by the Knights Templar Eye Foundation to A.M.'
- - 'Research Grant from the National Eye Institute (1R01EY027402-02) to A.M. and M.C.S.'
- - 'Emmy Noether grant 2806/1 to M.C.S.'
- - 'ERC grant OptoVision 637638 to M.C.S.'
- references: []
- resourcetype: Dataset
- templateversion: 1.2
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