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+# Metadata for DOI registration according to DataCite Metadata Schema 4.1.
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+# For detailed schema description see https://doi.org/10.5438/0014
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+
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+## Required fields
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+
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+# The main researchers involved. Include digital identifier (e.g., ORCID)
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+# if possible, including the prefix to indicate its type.
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+authors:
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+ -
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+ firstname: "Fikret Emre"
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+ lastname: "Kapucu"
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+ affiliation: "Neuro Group, Faculty of Medicine and Health Technology, Tampere University"
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+ id: "ORCID:0000-0002-4557-6885"
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+ -
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+ firstname: "Andrey"
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+ lastname: "Vinogradov"
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+ affiliation: "Neuro Group, Faculty of Medicine and Health Technology, Tampere University"
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+ id: "ORCID:0000-0003-1894-773X"
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+ -
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+ firstname: "Tanja"
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+ lastname: "Hyvärinen"
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+ affiliation: "Neuro Group, Faculty of Medicine and Health Technology, Tampere University"
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+ id: "0000-0002-8723-8817"
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+ -
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+ firstname: "Laura"
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+ lastname: "Ylä-Outinen"
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+ affiliation: "Neuro Group, Faculty of Medicine and Health Technology, Tampere University"
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+ id: "0000-0001-7817-9395"
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+ -
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+ firstname: "Susanna"
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+ lastname: "Narkilahti"
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+ affiliation: "Neuro Group, Faculty of Medicine and Health Technology, Tampere University"
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+ id: "0000-0002-7602-4418"
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+
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+
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+# A title to describe the published resource.
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+title: "Comparative microelectrode array dataset of the functional development of hPSC-derived and rat neuronal networks "
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+
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+# Additional information about the resource, e.g., a brief abstract.
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+description: |
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+ We provide a dataset of microelectrode array recordings (MEA) from human pluripotent stem cell (hPSC)-derived and
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+ rat embryonic cortical neurons during in vitro maturation and pharmacological treatment at their mature stage.
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+ Together with the recorded raw MEA data, we share the analysis code that produces the key scientific findings
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+ published previously with this dataset (Hyvärinen et al., 2019), including PCA analysis to reveal the distinction
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+ between rat and human cell activity features. The data enables evaluation and comparison of hPSC-derived and rat
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+ cortical cultures in terms of functional development and response to pharmacological treatment. The 12500 Hz
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+ sampled data is recorded with Axion 12-well plates (for developmental tracking) and 48-well plates (for
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+ pharmacological experiments). Raw data constitute time series of extracellularly recorded voltage values in Volts.
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+ The duration of the recordings varies from 10 to 30 minutes depending on the experimental set-up. Each raw MEA data
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+ file contains organised meta-data. This dataset is valuable for experimental and computational neuroscientists and
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+ any signal analyst with interest for neuronal signalling. The accurate detailed description of data is delivered in
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+ the corresponding publication (Kapucu et al., submitted).
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+
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+# Lit of keywords the resource should be associated with.
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+# Give as many keywords as possible, to make the resource findable.
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+keywords:
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+ - Neuroscience
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+ - Electrophysiology
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+ - Microelectrode array
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+ - MEA
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+ - Extracellular recordings
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+ - Action potential
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+ - Neuronal connectivity
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+ - Spike analysis
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+ - Burst analysis
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+ - Stem cell-derived neurons
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+ - Neuronal network development
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+
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+# License information for this resource. Please provide the license name and/or a link to the license.
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+# Please add also a corresponding LICENSE file to the repository.
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+license:
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+ name: "Creative Commons Attribution-NonCommercial 4.0 International License"
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+ url: "https://creativecommons.org/licenses/by-nc/4.0/"
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+
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+
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+
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+## Optional Fields
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+
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+# Funding information for this resource.
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+# Separate funder name and grant number by comma.
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+funding:
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+ - "Academy of Finland, 332693 (Fikret Emre Kapucu), 286990/326436 (Laura Ylä-Outinen), 312414 and 311017 (Susanna Narkilahti)"
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+ - "Orion Research Foundation, grant for postdoctoral research 2019 (Fikret Emre Kapucu), grant for doctoral dissertation work 2020 (Andrey Vinogradov)"
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+
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+
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+# Related publications. reftype might be: IsSupplementTo, IsDescribedBy, IsReferencedBy.
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+# Please provide digital identifier (e.g., DOI) if possible.
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+# Add a prefix to the ID, separated by a colon, to indicate the source.
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+# Supported sources are: DOI, arXiv, PMID
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+# In the citation field, please provide the full reference, including title, authors, journal etc.
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+references:
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+ -
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+ id: "doi:10.xxx/zzzz"
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+ reftype: "IsDescribedBy"
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+ citation: "Kapucu, F.E., Vinogradov A., Hyvärinen T., Ylä-Outinen L., Narkilahti S. (2021, submitted). Comparative microelectrode array dataset of functional development of human PSC-derived and rat neuronal networks"
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+ -
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+ id: "doi:10.1038/s41598-019-53647-8"
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+ reftype: "IsSupplementTo"
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+ citation: "Hyvärinen, T., Hyysalo, A., Kapucu, F.E., Aarnos, L., Vinogradov, A., Eglen, J.E., Ylä-Outinen, L., Narkilahti, S. (2019). Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate: comparison to rat cortical cultures. Scientific Reports volume 9, 17125."
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+
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+
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+# Resource type. Default is Dataset, other possible values are Software, DataPaper, Image, Text.
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+resourcetype: DataPaper
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+
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+# Do not edit or remove the following line
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+templateversion: 1.2
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