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-# Comparative microelectrode array dataset of functional development of human PSC-derived and rat neuronal networks 
+# Comparative microelectrode array dataset of functional development of human pluripotent stem cell-derived and rat neuronal networks 
 
 ## Summary
 
-We provide a dataset of microelectrode array recordings (MEA) from human pluripotent stem cell (hPSC)-derived and rat embryonic cortical neurons during in vitro maturation and pharmacological treatment at their mature stage ([Kapucu et al., submitted](http://doi.org/to-be-inserted-after-publication)). Together with the recorded raw MEA data, we share the analysis code that produces the key scientific findings published previously with this dataset ([Hyvärinen et al., 2019](https://doi.org/10.1038/s41598-019-53647-8)), including PCA analysis to reveal the distinction between rat and human cell activity features. The data enables evaluation and comparison of hPSC-derived and rat cortical cultures in terms of functional development and response to pharmacological treatment. The data is recorded with Axion 12-well plates (developmental tracking) and 48-well plates (pharmacology), sampled at 12500 Hz. Raw data constitute time series of extracellularly recorded voltage valeus in Volts. The duration of the recordings varies from 10 to 30 minutes depending on the experimental set-up. Each raw MEA data file contains organised meta-data. This dataset may be advantageous for experimental and computational neuroscientists and any signal analyst with interest for neuronal signalling. The accurate detailed description of data is delivered in the corresponding publication. Please, refer to the publication, as the current instructions deliver only a brief introduction of the data and relevant procedures.
+We provide a dataset of microelectrode array recordings (MEA) from human pluripotent stem cell (hPSC)-derived and rat embryonic cortical neurons during in vitro maturation and pharmacological treatment at their mature stage ([Kapucu et al., submitted](http://doi.org/to-be-inserted-after-publication)). Together with the recorded raw MEA data, we share the analysis code that produces the key scientific findings published previously with this dataset ([Hyvärinen et al., 2019](https://doi.org/10.1038/s41598-019-53647-8)), including PCA analysis to reveal the distinction between rat and human cell activity features. The data enables evaluation and comparison of hPSC-derived and rat cortical cultures in terms of functional development and response to pharmacological treatment. The 12500 Hz sampled data is recorded with Axion 12-well plates (for developmental tracking) and 48-well plates (for pharmacological experiments). Raw data constitute time series of extracellularly recorded voltage values in Volts. The duration of the recordings varies from 10 to 30 minutes depending on the experimental set-up. Each raw MEA data file contains organised meta-data. This dataset is valuable for experimental and computational neuroscientists and any signal analyst with interest for neuronal signalling. The accurate detailed description of data is delivered in the corresponding publication. Please, refer to the publication, as this README.md file deliver only a brief introduction of the data and basic procedures of reading it.
 
 ## Downloading the data
 
@@ -64,7 +64,7 @@ The attribute reading command is a bit different. For example, to read MEA plate
 *h5readatt('...path/hPSC_20517_MEA1_DIV3.h5', '/DataInfo', 'Plate type')* 
 
 Each folder also contains two sub-folders:
-* *\<data label\>_spikes_noise_explogs* <- the folder with detected spike .csv files (Matlab outputs) and explog and noisy electrodes .csv files (which all together comprise meaRtools input). 
+* *\<data label\>_spikes_noise_explogs* <- the folder with detected spike .csv files (MATLAB outputs) and explog and noisy electrodes .csv files (which all together comprise meaRtools input). 
 * *\<data label\>_meaRtools_output* <- the folder with selected meaRtools outputs (those, used in *Hyvärinen et al., 2019*)
 
 Pharmacology folders contain separate sub-folders for each stage of the pharmacological experiment (Baseline Pharmacology and TTX treatment). To check which well of MEA plate has undergone which specific treatment (e.g. drug or control) during Pharmacology and TTX stage it is recommended to take a glance into explog .csv file (to be found in the corresponding *\<data label\>_spikes_noise_explogs* sub-folder).