Annika Hagemann 3 лет назад
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      README.md

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README.md

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-# binned_spiking_activity_human_epilepsy
+# Preictal and interictal neuronal activity from the medial temporal lobe of patients with focal epilepsy
 
-Preictal and interictal neuronal activity from the medial temporal lobe of patients with focal epilepsy
+## Summary
+This dataset contains the binned activity times series of intracranial recordings from n=20 patients with medically intractable focal epilepsy. The data was recorded at the Department of Epileptology at the University of Bonn Medical Center. For pre-surgical evaluation, patients were implanted with depth electrodes in different regions of the medial temporal lobe, including hippocampus (H), amygdala (A), parahippocampal cortex (PHC) and entorhinal cortex (EC). 
+
+For each patient, the dataset contains one 10-minute reference recording (interictal), obtained in a seizure-free interval, as well as several pre-ictal recordings, spanning 10 minutes prior to seizure onset. Pre-ictal recordings end at seizure onset.
+
+The binned activity is defined as the number of recorded active neurons in a certain brain area in discrete time bins of 4 ms. For each recording, we provide the binned activities in left and right hippocampus (LH/RH), amygdala (LA/RA), parahippocampal cortex (LPHC/RPHC), entorhinal cortex (LEC/REC), and the full medial temporal lobe (left/right).
+For more details on the data acquisition and pre-processing, see [ref].
+
+
+## Repository structure
+
+### Data
+* patients.txt contains a list of patientIDs, the location of the epileptic focus and the surgery outcome
+* preIct_recordings_patients.txt contains a list of all preictal recordings and the corresponding patientID
+* interictal/* contains all interictal (reference) recordings
+* preictal/* contains all preictal recordings
+
+
+### Python Code
+Python scripts to estimate the distance to criticality using the Multistep Regression estimator [ref] and to reproduce the results shown in [ref].
+
+## Cite as
+Reference: Assessing criticality in pre-seizure single neuron activity of human epileptic cortex.
+
+## Related Publications
+* Reference: Assessing criticality in pre-seizure single neuron activity of human epileptic cortex.
+* Reference: MR estimator
+
+## Licensing
+See `LICENSE.txt` for the full license.