HL23VIP_950.cell.nml 823 KB

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  3. <notes>Cell: HL23VIP exported from NEURON ModelView. Reference: Yao, H. K.; Guet-McCreight, A.; Mazza, F.; Moradi Chameh, H.; Prevot, T. D.; Griffiths, J. D.; Tripathy, S. J.; Valiante, T. A.; Sibille, E. &amp; Hay, E. Reduced inhibition in depression impairs stimulus processing in human cortical microcircuits Cell Reports, Elsevier, 2022, 38</notes>
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  12029. These segmentGroups correspond to the 'cables' of NeuroML v1.8.1, and map to/from NEURON sections.</notes>
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  12081. <notes>This group contains an unbranched set of segments, and all of the segmentGroups marked with
  12082. neuroLexId = sao864921383 form a non-overlapping set of all of the segments.
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  12108. <notes>This group contains an unbranched set of segments, and all of the segmentGroups marked with
  12109. neuroLexId = sao864921383 form a non-overlapping set of all of the segments.
  12110. These segmentGroups correspond to the 'cables' of NeuroML v1.8.1, and map to/from NEURON sections.</notes>
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  12119. <notes>This group contains an unbranched set of segments, and all of the segmentGroups marked with
  12120. neuroLexId = sao864921383 form a non-overlapping set of all of the segments.
  12121. These segmentGroups correspond to the 'cables' of NeuroML v1.8.1, and map to/from NEURON sections.</notes>
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  12137. neuroLexId = sao864921383 form a non-overlapping set of all of the segments.
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  14885. <member segment="1326"/>
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  14909. <member segment="1350"/>
  14910. <member segment="1351"/>
  14911. </segmentGroup>
  14912. <segmentGroup id="dend_26" neuroLexId="sao864921383">
  14913. <notes>This group contains an unbranched set of segments, and all of the segmentGroups marked with
  14914. neuroLexId = sao864921383 form a non-overlapping set of all of the segments.
  14915. These segmentGroups correspond to the 'cables' of NeuroML v1.8.1, and map to/from NEURON sections.</notes>
  14916. <member segment="1011"/>
  14917. <member segment="1012"/>
  14918. <member segment="1013"/>
  14919. <member segment="1014"/>
  14920. <member segment="1015"/>
  14921. <member segment="1016"/>
  14922. <member segment="1017"/>
  14923. <member segment="1018"/>
  14924. <member segment="1019"/>
  14925. <member segment="1020"/>
  14926. <member segment="1021"/>
  14927. <member segment="1022"/>
  14928. <member segment="1023"/>
  14929. <member segment="1024"/>
  14930. <member segment="1025"/>
  14931. <member segment="1026"/>
  14932. <member segment="1027"/>
  14933. <member segment="1028"/>
  14934. <member segment="1029"/>
  14935. <member segment="1030"/>
  14936. <member segment="1031"/>
  14937. <member segment="1032"/>
  14938. <member segment="1033"/>
  14939. <member segment="1034"/>
  14940. <member segment="1035"/>
  14941. <member segment="1036"/>
  14942. <member segment="1037"/>
  14943. </segmentGroup>
  14944. <segmentGroup id="dend_28" neuroLexId="sao864921383">
  14945. <notes>This group contains an unbranched set of segments, and all of the segmentGroups marked with
  14946. neuroLexId = sao864921383 form a non-overlapping set of all of the segments.
  14947. These segmentGroups correspond to the 'cables' of NeuroML v1.8.1, and map to/from NEURON sections.</notes>
  14948. <property tag="numberInternalDivisions" value="7"/>
  14949. <annotation>
  14950. <property xmlns="http://www.neuroml.org/schema/neuroml2" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xs="http://www.w3.org/2001/XMLSchema" tag="numberInternalDivisions" value="7"/>
  14951. </annotation>
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  14954. <member segment="1187"/>
  14955. <member segment="1188"/>
  14956. <member segment="1189"/>
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  14959. <member segment="1192"/>
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  14967. <member segment="1200"/>
  14968. <member segment="1201"/>
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  14971. <member segment="1204"/>
  14972. <member segment="1205"/>
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  14975. <member segment="1208"/>
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  14987. <member segment="1220"/>
  14988. <member segment="1221"/>
  14989. <member segment="1222"/>
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  15007. <member segment="1240"/>
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  15011. <member segment="1244"/>
  15012. <member segment="1245"/>
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  15019. <member segment="1252"/>
  15020. <member segment="1253"/>
  15021. <member segment="1254"/>
  15022. <member segment="1255"/>
  15023. <member segment="1256"/>
  15024. <member segment="1257"/>
  15025. <member segment="1258"/>
  15026. <member segment="1259"/>
  15027. <member segment="1260"/>
  15028. <member segment="1261"/>
  15029. <member segment="1262"/>
  15030. <member segment="1263"/>
  15031. <member segment="1264"/>
  15032. <member segment="1265"/>
  15033. <member segment="1266"/>
  15034. <member segment="1267"/>
  15035. <member segment="1268"/>
  15036. <member segment="1269"/>
  15037. <member segment="1270"/>
  15038. <member segment="1271"/>
  15039. <member segment="1272"/>
  15040. <member segment="1273"/>
  15041. <member segment="1274"/>
  15042. <member segment="1275"/>
  15043. <member segment="1276"/>
  15044. <member segment="1277"/>
  15045. <member segment="1278"/>
  15046. <member segment="1279"/>
  15047. <member segment="1280"/>
  15048. <member segment="1281"/>
  15049. <member segment="1282"/>
  15050. <member segment="1283"/>
  15051. <member segment="1284"/>
  15052. <member segment="1285"/>
  15053. <member segment="1286"/>
  15054. <member segment="1287"/>
  15055. <member segment="1288"/>
  15056. <member segment="1289"/>
  15057. <member segment="1290"/>
  15058. <member segment="1291"/>
  15059. <member segment="1292"/>
  15060. <member segment="1293"/>
  15061. <member segment="1294"/>
  15062. <member segment="1295"/>
  15063. <member segment="1296"/>
  15064. <member segment="1297"/>
  15065. <member segment="1298"/>
  15066. <member segment="1299"/>
  15067. <member segment="1300"/>
  15068. <member segment="1301"/>
  15069. <member segment="1302"/>
  15070. <member segment="1303"/>
  15071. <member segment="1304"/>
  15072. <member segment="1305"/>
  15073. </segmentGroup>
  15074. <segmentGroup id="dend_27" neuroLexId="sao864921383">
  15075. <notes>This group contains an unbranched set of segments, and all of the segmentGroups marked with
  15076. neuroLexId = sao864921383 form a non-overlapping set of all of the segments.
  15077. These segmentGroups correspond to the 'cables' of NeuroML v1.8.1, and map to/from NEURON sections.</notes>
  15078. <property tag="numberInternalDivisions" value="9"/>
  15079. <annotation>
  15080. <property xmlns="http://www.neuroml.org/schema/neuroml2" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xs="http://www.w3.org/2001/XMLSchema" tag="numberInternalDivisions" value="9"/>
  15081. </annotation>
  15082. <member segment="1038"/>
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  15085. <member segment="1041"/>
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  15087. <member segment="1043"/>
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  15089. <member segment="1045"/>
  15090. <member segment="1046"/>
  15091. <member segment="1047"/>
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  15094. <member segment="1050"/>
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  15096. <member segment="1052"/>
  15097. <member segment="1053"/>
  15098. <member segment="1054"/>
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  15100. <member segment="1056"/>
  15101. <member segment="1057"/>
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  15103. <member segment="1059"/>
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  15105. <member segment="1061"/>
  15106. <member segment="1062"/>
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  15111. <member segment="1067"/>
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  15116. <member segment="1072"/>
  15117. <member segment="1073"/>
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  15119. <member segment="1075"/>
  15120. <member segment="1076"/>
  15121. <member segment="1077"/>
  15122. <member segment="1078"/>
  15123. <member segment="1079"/>
  15124. <member segment="1080"/>
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  15126. <member segment="1082"/>
  15127. <member segment="1083"/>
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  15131. <member segment="1087"/>
  15132. <member segment="1088"/>
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  15134. <member segment="1090"/>
  15135. <member segment="1091"/>
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  15137. <member segment="1093"/>
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  15139. <member segment="1095"/>
  15140. <member segment="1096"/>
  15141. <member segment="1097"/>
  15142. <member segment="1098"/>
  15143. <member segment="1099"/>
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  15145. <member segment="1101"/>
  15146. <member segment="1102"/>
  15147. <member segment="1103"/>
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  15149. <member segment="1105"/>
  15150. <member segment="1106"/>
  15151. <member segment="1107"/>
  15152. <member segment="1108"/>
  15153. <member segment="1109"/>
  15154. <member segment="1110"/>
  15155. <member segment="1111"/>
  15156. <member segment="1112"/>
  15157. <member segment="1113"/>
  15158. <member segment="1114"/>
  15159. <member segment="1115"/>
  15160. <member segment="1116"/>
  15161. <member segment="1117"/>
  15162. <member segment="1118"/>
  15163. <member segment="1119"/>
  15164. <member segment="1120"/>
  15165. <member segment="1121"/>
  15166. <member segment="1122"/>
  15167. <member segment="1123"/>
  15168. <member segment="1124"/>
  15169. <member segment="1125"/>
  15170. <member segment="1126"/>
  15171. <member segment="1127"/>
  15172. <member segment="1128"/>
  15173. <member segment="1129"/>
  15174. <member segment="1130"/>
  15175. <member segment="1131"/>
  15176. <member segment="1132"/>
  15177. <member segment="1133"/>
  15178. <member segment="1134"/>
  15179. <member segment="1135"/>
  15180. <member segment="1136"/>
  15181. <member segment="1137"/>
  15182. <member segment="1138"/>
  15183. <member segment="1139"/>
  15184. <member segment="1140"/>
  15185. <member segment="1141"/>
  15186. <member segment="1142"/>
  15187. <member segment="1143"/>
  15188. <member segment="1144"/>
  15189. <member segment="1145"/>
  15190. <member segment="1146"/>
  15191. <member segment="1147"/>
  15192. <member segment="1148"/>
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  15194. <member segment="1150"/>
  15195. <member segment="1151"/>
  15196. <member segment="1152"/>
  15197. <member segment="1153"/>
  15198. <member segment="1154"/>
  15199. <member segment="1155"/>
  15200. <member segment="1156"/>
  15201. <member segment="1157"/>
  15202. <member segment="1158"/>
  15203. <member segment="1159"/>
  15204. <member segment="1160"/>
  15205. <member segment="1161"/>
  15206. <member segment="1162"/>
  15207. <member segment="1163"/>
  15208. <member segment="1164"/>
  15209. <member segment="1165"/>
  15210. <member segment="1166"/>
  15211. <member segment="1167"/>
  15212. <member segment="1168"/>
  15213. <member segment="1169"/>
  15214. <member segment="1170"/>
  15215. <member segment="1171"/>
  15216. <member segment="1172"/>
  15217. <member segment="1173"/>
  15218. <member segment="1174"/>
  15219. <member segment="1175"/>
  15220. <member segment="1176"/>
  15221. <member segment="1177"/>
  15222. <member segment="1178"/>
  15223. <member segment="1179"/>
  15224. <member segment="1180"/>
  15225. <member segment="1181"/>
  15226. <member segment="1182"/>
  15227. <member segment="1183"/>
  15228. <member segment="1184"/>
  15229. </segmentGroup>
  15230. <segmentGroup id="soma_group" neuroLexId="GO:0043025">
  15231. <notes>Default soma segment group for the cell</notes>
  15232. <include segmentGroup="soma_0"/>
  15233. </segmentGroup>
  15234. <segmentGroup id="axon_group" neuroLexId="GO:0030424">
  15235. <notes>Default axon segment group for the cell</notes>
  15236. <include segmentGroup="axon_0"/>
  15237. <include segmentGroup="axon_1"/>
  15238. </segmentGroup>
  15239. <segmentGroup id="dendrite_group" neuroLexId="GO:0030425">
  15240. <notes>Default dendrite segment group for the cell</notes>
  15241. <include segmentGroup="dend_0"/>
  15242. <include segmentGroup="dend_1"/>
  15243. <include segmentGroup="dend_2"/>
  15244. <include segmentGroup="dend_3"/>
  15245. <include segmentGroup="dend_4"/>
  15246. <include segmentGroup="dend_5"/>
  15247. <include segmentGroup="dend_6"/>
  15248. <include segmentGroup="dend_7"/>
  15249. <include segmentGroup="dend_8"/>
  15250. <include segmentGroup="dend_9"/>
  15251. <include segmentGroup="dend_10"/>
  15252. <include segmentGroup="dend_11"/>
  15253. <include segmentGroup="dend_12"/>
  15254. <include segmentGroup="dend_13"/>
  15255. <include segmentGroup="dend_14"/>
  15256. <include segmentGroup="dend_15"/>
  15257. <include segmentGroup="dend_16"/>
  15258. <include segmentGroup="dend_17"/>
  15259. <include segmentGroup="dend_18"/>
  15260. <include segmentGroup="dend_19"/>
  15261. <include segmentGroup="dend_20"/>
  15262. <include segmentGroup="dend_21"/>
  15263. <include segmentGroup="dend_22"/>
  15264. <include segmentGroup="dend_23"/>
  15265. <include segmentGroup="dend_24"/>
  15266. <include segmentGroup="dend_25"/>
  15267. <include segmentGroup="dend_26"/>
  15268. <include segmentGroup="dend_27"/>
  15269. <include segmentGroup="dend_28"/>
  15270. <include segmentGroup="dend_29"/>
  15271. <include segmentGroup="dend_30"/>
  15272. <include segmentGroup="dend_31"/>
  15273. <include segmentGroup="dend_32"/>
  15274. <include segmentGroup="dend_33"/>
  15275. <include segmentGroup="dend_34"/>
  15276. <include segmentGroup="dend_35"/>
  15277. <include segmentGroup="dend_36"/>
  15278. <include segmentGroup="dend_37"/>
  15279. <include segmentGroup="dend_38"/>
  15280. <include segmentGroup="dend_39"/>
  15281. <include segmentGroup="dend_40"/>
  15282. <include segmentGroup="dend_41"/>
  15283. <include segmentGroup="dend_42"/>
  15284. <include segmentGroup="dend_43"/>
  15285. <include segmentGroup="dend_44"/>
  15286. <include segmentGroup="dend_45"/>
  15287. <include segmentGroup="dend_46"/>
  15288. <include segmentGroup="dend_47"/>
  15289. <include segmentGroup="dend_48"/>
  15290. <include segmentGroup="dend_49"/>
  15291. <include segmentGroup="dend_50"/>
  15292. <include segmentGroup="dend_51"/>
  15293. <include segmentGroup="dend_52"/>
  15294. </segmentGroup>
  15295. <segmentGroup id="all">
  15296. <include segmentGroup="axon_0"/>
  15297. <include segmentGroup="axon_1"/>
  15298. <include segmentGroup="dend_0"/>
  15299. <include segmentGroup="dend_1"/>
  15300. <include segmentGroup="dend_2"/>
  15301. <include segmentGroup="dend_3"/>
  15302. <include segmentGroup="dend_4"/>
  15303. <include segmentGroup="dend_5"/>
  15304. <include segmentGroup="dend_6"/>
  15305. <include segmentGroup="dend_7"/>
  15306. <include segmentGroup="dend_8"/>
  15307. <include segmentGroup="dend_9"/>
  15308. <include segmentGroup="dend_10"/>
  15309. <include segmentGroup="dend_11"/>
  15310. <include segmentGroup="dend_12"/>
  15311. <include segmentGroup="dend_13"/>
  15312. <include segmentGroup="dend_14"/>
  15313. <include segmentGroup="dend_15"/>
  15314. <include segmentGroup="dend_16"/>
  15315. <include segmentGroup="dend_17"/>
  15316. <include segmentGroup="dend_18"/>
  15317. <include segmentGroup="dend_19"/>
  15318. <include segmentGroup="dend_20"/>
  15319. <include segmentGroup="dend_21"/>
  15320. <include segmentGroup="dend_22"/>
  15321. <include segmentGroup="dend_23"/>
  15322. <include segmentGroup="dend_24"/>
  15323. <include segmentGroup="dend_25"/>
  15324. <include segmentGroup="dend_26"/>
  15325. <include segmentGroup="dend_27"/>
  15326. <include segmentGroup="dend_28"/>
  15327. <include segmentGroup="dend_29"/>
  15328. <include segmentGroup="dend_30"/>
  15329. <include segmentGroup="dend_31"/>
  15330. <include segmentGroup="dend_32"/>
  15331. <include segmentGroup="dend_33"/>
  15332. <include segmentGroup="dend_34"/>
  15333. <include segmentGroup="dend_35"/>
  15334. <include segmentGroup="dend_36"/>
  15335. <include segmentGroup="dend_37"/>
  15336. <include segmentGroup="dend_38"/>
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  15339. <include segmentGroup="dend_41"/>
  15340. <include segmentGroup="dend_42"/>
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  15348. <include segmentGroup="dend_50"/>
  15349. <include segmentGroup="dend_51"/>
  15350. <include segmentGroup="dend_52"/>
  15351. <include segmentGroup="soma_0"/>
  15352. </segmentGroup>
  15353. </morphology>
  15354. <biophysicalProperties id="biophys">
  15355. <membraneProperties>
  15356. <channelDensity id="pas" ionChannel="pas" condDensity="2.5756438955642182e-05 S_per_cm2" erev="-79.74132024971513 mV" ion="non_specific"/>
  15357. <channelDensity id="Ih" ionChannel="Ih" condDensity="4.274951616063423e-05 S_per_cm2" erev="-45 mV" ion="hcn"/>
  15358. <channelDensity id="NaTg_somatic" ionChannel="NaTg_VIP_somatic" condDensity="0.11491205828369114 S_per_cm2" erev="50 mV" segmentGroup="soma_group" ion="na"/>
  15359. <channelDensity id="Nap_somatic" ionChannel="Nap" condDensity="0.0001895305240694194 S_per_cm2" erev="50 mV" segmentGroup="soma_group" ion="na"/>
  15360. <channelDensity id="K_P_somatic" ionChannel="K_P" condDensity="0.0009925418924114282 S_per_cm2" erev="-85 mV" segmentGroup="soma_group" ion="k"/>
  15361. <channelDensity id="K_T_somatic" ionChannel="K_T" condDensity="0.009051981253674193 S_per_cm2" erev="-85 mV" segmentGroup="soma_group" ion="k"/>
  15362. <channelDensity id="Kv3_1_somatic" ionChannel="Kv3_1" condDensity="0.31215653649208114 S_per_cm2" erev="-85 mV" segmentGroup="soma_group" ion="k"/>
  15363. <channelDensity id="Im_somatic" ionChannel="Im" condDensity="0.0003679378262289559 S_per_cm2" erev="-85 mV" segmentGroup="soma_group" ion="k"/>
  15364. <channelDensity id="SK_somatic" ionChannel="SK" condDensity="0.1655502166633749 S_per_cm2" erev="-85 mV" segmentGroup="soma_group" ion="k"/>
  15365. <channelDensity id="NaTg_axonal" ionChannel="NaTg_VIP_axonal" condDensity="0.20112200814143477 S_per_cm2" erev="50 mV" segmentGroup="axon_group" ion="na"/>
  15366. <channelDensity id="Nap_axonal" ionChannel="Nap" condDensity="0.0006248906854665301 S_per_cm2" erev="50 mV" segmentGroup="axon_group" ion="na"/>
  15367. <channelDensity id="K_P_axonal" ionChannel="K_P" condDensity="0.26489876414660096 S_per_cm2" erev="-85 mV" segmentGroup="axon_group" ion="k"/>
  15368. <channelDensity id="K_T_axonal" ionChannel="K_T" condDensity="0.014364427062274185 S_per_cm2" erev="-85 mV" segmentGroup="axon_group" ion="k"/>
  15369. <channelDensity id="Kv3_1_axonal" ionChannel="Kv3_1" condDensity="0.0011201608191112877 S_per_cm2" erev="-85 mV" segmentGroup="axon_group" ion="k"/>
  15370. <channelDensity id="Im_axonal" ionChannel="Im" condDensity="0.00013891465461042372 S_per_cm2" erev="-85 mV" segmentGroup="axon_group" ion="k"/>
  15371. <channelDensity id="SK_axonal" ionChannel="SK" condDensity="0.7027792087501376 S_per_cm2" erev="-85 mV" segmentGroup="axon_group" ion="k"/>
  15372. <channelDensityNernst id="Ca_HVA_somatic" ionChannel="Ca_HVA" condDensity="4.384846294634834e-05 S_per_cm2" segmentGroup="soma_group" ion="ca"/>
  15373. <channelDensityNernst id="Ca_LVA_somatic" ionChannel="Ca_LVA" condDensity="0.0034472458995879864 S_per_cm2" segmentGroup="soma_group" ion="ca"/>
  15374. <channelDensityNernst id="Ca_HVA_axonal" ionChannel="Ca_HVA" condDensity="2.819397237794038e-05 S_per_cm2" segmentGroup="axon_group" ion="ca"/>
  15375. <channelDensityNernst id="Ca_LVA_axonal" ionChannel="Ca_LVA" condDensity="0.010354001513952075 S_per_cm2" segmentGroup="axon_group" ion="ca"/>
  15376. <specificCapacitance value="2 uF_per_cm2"/>
  15377. <initMembPotential value="-80mV"/>
  15378. </membraneProperties>
  15379. <intracellularProperties>
  15380. <species id="ca" concentrationModel="CaDynamics_E2_NML2_VIP_somatic" ion="ca" initialConcentration="1e-4 mM" initialExtConcentration="2.0E-6 mol_per_cm3" segmentGroup="soma_group"/>
  15381. <species id="ca" concentrationModel="CaDynamics_E2_NML2_VIP_axonal" ion="ca" initialConcentration="1e-4 mM" initialExtConcentration="2.0E-6 mol_per_cm3" segmentGroup="axon_group"/>
  15382. <resistivity value="0.1 kohm_cm"/>
  15383. </intracellularProperties>
  15384. </biophysicalProperties>
  15385. </cell>
  15386. </neuroml>