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Merge remote-tracking branch 'refs/remotes/Comparative_MEA_dataset/master'

Andrey Vinogradov 3 years ago
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+# Metadata for DOI registration according to DataCite Metadata Schema 4.1.
+# For detailed schema description see https://doi.org/10.5438/0014
+
+## Required fields
+
+# The main researchers involved. Include digital identifier (e.g., ORCID)
+# if possible, including the prefix to indicate its type.
+authors:
+  -
+    firstname: "Fikret Emre"
+    lastname: "Kapucu"
+    affiliation: "Neuro Group, Faculty of Medicine and Health Technology, Tampere University"
+    id: "ORCID:0000-0002-4557-6885"
+  -
+    firstname: "Andrey"
+    lastname: "Vinogradov"
+    affiliation: "Neuro Group, Faculty of Medicine and Health Technology, Tampere University"
+    id: "ORCID:0000-0003-1894-773X"
+  -
+    firstname: "Tanja"
+    lastname: "Hyvärinen"
+    affiliation: "Neuro Group, Faculty of Medicine and Health Technology, Tampere University"
+    id: "0000-0002-8723-8817"
+  -
+    firstname: "Laura"
+    lastname: "Ylä-Outinen"
+    affiliation: "Neuro Group, Faculty of Medicine and Health Technology, Tampere University"
+    id: "0000-0001-7817-9395"
+  -
+    firstname: "Susanna"
+    lastname: "Narkilahti"
+    affiliation: "Neuro Group, Faculty of Medicine and Health Technology, Tampere University"
+    id: "0000-0002-7602-4418"
+    
+
+# A title to describe the published resource.
+title: "Comparative microelectrode array dataset of the functional development of hPSC-derived and rat neuronal networks "
+
+# Additional information about the resource, e.g., a brief abstract.
+description: |
+  We provide a dataset of microelectrode array recordings (MEA) from human pluripotent stem cell (hPSC)-derived and 
+  rat embryonic cortical neurons during in vitro maturation and pharmacological treatment at their mature stage. 
+  Together with the recorded raw MEA data, we share the analysis code that produces the key scientific findings
+  published previously with this dataset (Hyvärinen et al., 2019), including PCA analysis to reveal the distinction
+  between rat and human cell activity features. The data enables evaluation and comparison of hPSC-derived and rat 
+  cortical cultures in terms of functional development and response to pharmacological treatment. The 12500 Hz 
+  sampled data is recorded with Axion 12-well plates (for developmental tracking) and 48-well plates (for 
+  pharmacological experiments). Raw data constitute time series of extracellularly recorded voltage values in Volts.
+  The duration of the recordings varies from 10 to 30 minutes depending on the experimental set-up. Each raw MEA data
+  file contains organised meta-data. This dataset is valuable for experimental and computational neuroscientists and
+  any signal analyst with interest for neuronal signalling. The accurate detailed description of data is delivered in
+  the corresponding publication (Kapucu et al., submitted).
+
+# Lit of keywords the resource should be associated with.
+# Give as many keywords as possible, to make the resource findable.
+keywords:
+  - Neuroscience
+  - Electrophysiology
+  - Microelectrode array
+  - MEA
+  - Extracellular recordings
+  - Action potential
+  - Neuronal connectivity
+  - Spike analysis
+  - Burst analysis
+  - Stem cell-derived neurons
+  - Neuronal network development
+
+# License information for this resource. Please provide the license name and/or a link to the license.
+# Please add also a corresponding LICENSE file to the repository.
+license:
+  name: "Creative Commons Attribution-NonCommercial 4.0 International License"
+  url: "https://creativecommons.org/licenses/by-nc/4.0/"
+
+
+
+## Optional Fields
+
+# Funding information for this resource.
+# Separate funder name and grant number by comma.
+funding:
+  - "Academy of Finland, 332693 (Fikret Emre Kapucu), 286990/326436 (Laura Ylä-Outinen), 312414 and 311017 (Susanna Narkilahti)"
+  - "Orion Research Foundation, grant for postdoctoral research 2019 (Fikret Emre Kapucu), grant for doctoral dissertation work 2020 (Andrey Vinogradov)"
+
+
+# Related publications. reftype might be: IsSupplementTo, IsDescribedBy, IsReferencedBy.
+# Please provide digital identifier (e.g., DOI) if possible.
+# Add a prefix to the ID, separated by a colon, to indicate the source.
+# Supported sources are: DOI, arXiv, PMID
+# In the citation field, please provide the full reference, including title, authors, journal etc.
+references:
+  -
+    id: "doi:10.xxx/zzzz"
+    reftype: "IsDescribedBy"
+    citation: "Kapucu, F.E., Vinogradov A., Hyvärinen T., Ylä-Outinen L., Narkilahti S. (2021, submitted). Comparative microelectrode array dataset of functional development of human PSC-derived and rat neuronal networks"
+  -
+    id: "doi:10.1038/s41598-019-53647-8"
+    reftype: "IsSupplementTo"
+    citation: "Hyvärinen, T., Hyysalo, A., Kapucu, F.E., Aarnos, L., Vinogradov, A., Eglen, J.E., Ylä-Outinen, L., Narkilahti, S. (2019). Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate: comparison to rat cortical cultures. Scientific Reports volume 9, 17125."
+
+
+# Resource type. Default is Dataset, other possible values are Software, DataPaper, Image, Text.
+resourcetype: DataPaper
+
+# Do not edit or remove the following line
+templateversion: 1.2