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+# Metadata for DOI registration according to DataCite Metadata Schema 4.1.
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+# For detailed schema description see https://doi.org/10.5438/0014
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+
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+## Required fields
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+
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+# The main researchers involved. Include digital identifier (e.g., ORCID)
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+# if possible, including the prefix to indicate its type.
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+authors:
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+ -
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+ firstname: "Diana"
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+ lastname: "Kostyalik"
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+ affiliation: "Cognitive Pharmacology Laboratory, Department of Pharmacology and Drug Safety, Gedeon Richter Plc"
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+ id: "ORCID:0000-0003-3552-4528"
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+ -
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+ firstname: "Kristóf"
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+ lastname: "Kelemen"
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+ affiliation: "Cognitive Pharmacology Laboratory, Department of Pharmacology and Drug Safety, Gedeon Richter Plc"
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+ id: "ORCID:0000-0001-7378-0843"
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+
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+
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+# A title to describe the published resource.
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+title: "Response-related sensorimotor rhythms under scopolamine and MK-801 exposures in the touchscreen Visual Discrimination test in rats"
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+
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+# Additional information about the resource, e.g., a brief abstract.
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+description: |The human mu rhythm has been suggested to represent an important function in information processing. Rodent homologue rhythms have been assumed though no study has investigated them from the cognitive aspect yet. As voluntary goal-directed movements induce the desynchronization of mu rhythm, we aimed at exploring whether the touch-response-related brain activity during the touchscreen visual discrimination (VD) task is suitable to detect sensorimotor rhythms in healthy and cognitively impaired rats. Different doses of scopolamine or MK-801 were injected subcutaneously to male Lister Hooded rats, and epidural electroencephalography (EEG) was recorded during task performance. Arciform ~10 Hz oscillations appeared during visual processing, then two characteristic alpha/beta desynchronization-resynchronization patterns emerged predominating above the sensorimotor areas, serving different motor functions. Beyond causing cognitive impairment, both drugs supressed the touch-related upper alpha (10-15 Hz) reactivity for desynchronization. Reaction time positively correlated with movement-related alpha and beta power both in normal and impaired conditions. These results support the existence of a mu homologue rodent rhythm whose upper alpha component appeared to be modulated by cholinergic and glutamatergic mechanisms and its power change might indicate a potential EEG correlate of processing speed. The VD task can be utilized for the investigation of sensorimotor rhythms in rats.
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+ Example description
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+ that can contain linebreaks
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+ but has to maintain indentation.
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+
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+# Lit of keywords the resource should be associated with.
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+# Give as many keyworThe human mu rhythm has been suggested to represent an important function in information processing. Rodent homologue rhythms have been assumed though no study has investigated them from the cognitive aspect yet. As voluntary goal-directed movements induce the desynchronization of mu rhythm, we aimed at exploring whether the touch-response-related brain activity during the touchscreen visual discrimination (VD) task is suitable to detect sensorimotor rhythms in healthy and cognitively impaired rats. Different doses of scopolamine or MK-801 were injected subcutaneously to male Lister Hooded rats, and epidural electroencephalography (EEG) was recorded during task performance. Arciform ~10 Hz oscillations appeared during visual processing, then two characteristic alpha/beta desynchronization-resynchronization patterns emerged predominating above the sensorimotor areas, serving different motor functions. Beyond causing cognitive impairment, both drugs supressed the touch-related upper alpha (10-15 Hz) reactivity for desynchronization. Reaction time positively correlated with movement-related alpha and beta power both in normal and impaired conditions. These results support the existence of a mu homologue rodent rhythm whose upper alpha component appeared to be modulated by cholinergic and glutamatergic mechanisms and its power change might indicate a potential EEG correlate of processing speed. The VD task can be utilized for the investigation of sensorimotor rhythms in rats.ds as possible, to make the resource findable.
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+keywords:
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+ - Neuroscience
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+ - Visual Discrimination
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+ - EEG
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+ - Scopolamine
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+ - MK-801
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+
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+# License information for this resource. Please provide the license name and/or a link to the license.
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+# Please add also a corresponding LICENSE file to the repository.
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+license:
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+ name: "Creative Commons CC0 1.0 Public Domain Dedication"
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+ url: "https://creativecommons.org/publicdomain/zero/1.0/"
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+
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+
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+
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+## Optional Fields
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+
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+# Funding information for this resource.
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+# Separate funder name and grant number by comma.
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+funding:
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+ - "DFG, AB1234/5-6"
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+ - "EU, EU.12345"
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+
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+
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+# Related publications. reftype might be: IsSupplementTo, IsDescribedBy, IsReferencedBy.
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+# Please provide digital identifier (e.g., DOI) if possible.
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+# Add a prefix to the ID, separated by a colon, to indicate the source.
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+# Supported sources are: DOI, arXiv, PMID
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+# In the citation field, please provide the full reference, including title, authors, journal etc.
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+references:
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+ -
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+ id: "doi:10.xxx/zzzz"
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+ reftype: "IsSupplementTo"
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+ citation: "Citation1"
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+ -
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+ id: "arxiv:mmmm.nnnn"
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+ reftype: "IsSupplementTo"
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+ citation: "Citation2"
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+ -
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+ id: "pmid:nnnnnnnn"
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+ reftype: "IsReferencedBy"
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+ citation: "Citation3"
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+
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+
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+# Resource type. Default is Dataset, other possible values are Software, DataPaper, Image, Text.
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+resourcetype: Dataset
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+
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+# Do not edit or remove the following line
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+templateversion: 1.2
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