Excitatory neurons of the anterior cingulate cortex encode chosen actions and their outcomes rather than cognitive state

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README.md

Jendryka_et_al_ACC_imaging_5CSRTT_data

This repository contains the raw behavioral and pre-processed calcium imaging data for the publication 'Excitatory neurons of the anterior cingulate cortex encode chosen actions and their outcomes rather than cognitive state' by Jendryka et al. You find the code for reproducing the paper using this data on https://github.com/martinjendryka/Jendryka_et_al_ACC_imaging_5CSRTT.git

The files were compressed into zip files and are stored in the folders 'behavior' and 'miniscope', respectively.

Behavioral data

The behavioral data consists of .csv files for each animal and experimental session with three values (index number, timestamp in ms, task variable). The first 4 lines hold information about the session, i.e. 'experiment name' (blank), 'Task name, Subject ID, Project (blank), Start date.

Calcium imaging data

The calcium imaging data consists of timestamp files (timestamp.dat or timestamp.csv) and pre-processed calcium traces (traces.mat) for each animal and session.

The timestamp dat files have 4 values in each row: 'camNum' (0, not relevant), 'frameNum' (index number of recorded frame), 'sysClock' (timestamp in ms of recorded frame), 'buffer' (1, not relevant). The timestamp csv files have 3 values in each row: 'Frame Number' (index number of recorded frame), 'Time Stamp (ms)' (timestamp in ms of recorded frame), 'Buffer Index' (0, not relevant).

The calcium trace files contain three variables: 'traces' (2-D array, pre-processed calcium signal trace, dimensions: number of cells X number of frames), 'filters' (3-D array, spatial distribution of pre-processed calcium signal, number of frames according to length of FOV, number of frames according to width of FOV, number of cells). The third variable 'valid' can be ignored.

datacite.yml
Title Excitatory neurons of the anterior cingulate cortex encode chosen actions and their outcomes rather than cognitive state
Authors Jendryka,Martin;Institute of Applied Physiology, Ulm University, Ulm, Germany
Lewin,Uwe;Max-Planck-Institute for Biological Intelligence, Martinsried, Munich, Germany
Kapanaiah,Sampath;Institute of Applied Physiology, Ulm University, Ulm, Germany
Dermutz,Hartmut;Institute for Neuroinformatics, ETH Zürich, Zürich, Switzerland
Liss,Birgit;Institute of Applied Physiology, Ulm University, Ulm, Germany; Linacre College and New College, University of Oxford, Oxford, UK
Pekcec,Anton;Boehringer Ingelheim Pharma GmbH & Co. KG, Div. Research Germany, Biberach an der Riss, Germany
Akam,Thomas;Department of Experimental Psychology and Wellcome Centre for Integrative Neuroimaging, University of Oxford, Oxford, UK
Grewe,Benjamin;Institute for Neuroinformatics, ETH Zürich, Zürich, Switzerland
Kätzel,Dennis;Institute of Applied Physiology, Ulm University, Ulm, Germany
Description Data repository containing raw behavioral and pre-processed calcium imaging data for reproducing study. Data was recorded in mice while performing the 5-choice-serial-reaction-time-task holding miniature fluorescence microscopes ('miniscopes') for calcium imaging. For details, refer to the cited publications.
License Creative Commons CC0 1.0 Public Domain Dedication (https://creativecommons.org/publicdomain/zero/1.0/)
References Excitatory neurons of the anterior cingulate cortex encode chosen actions and their outcomes rather than cognitive state, Martin M. Jendryka, Uwe Lewin, Sampath K.T. Kapanaiah, Hartmut Dermutz, Birgit Liss, Anton Pekcec, Thomas Akam, Benjamin Grewe, Dennis Kaetzel, bioRxiv 2024.04.12.589244; doi: https://doi.org/10.1101/2024.04.12.589244 [doi:10.1101/2024.04.12.589244] (IsSupplementTo)
Funding Boehringer Ingelheim-Ulm University (BIU) Center (TPN010)
Else-Kroener-Fresenius/German-Scholars-Organization Programme for excellent medical scientists from abroad (GSO/EKFS 12)
DFG (KA 4594/2-1)
Alfried-Krupp Foundation
Keywords anterior cingulate cortex
5-CSRTT
calcium imaging
neural dynamics
devaluation
impulse control
sustained attention
miniscope
prefrontal cortex
reward value
cognitive control
Resource Type Dataset