Guidali_et_al_2023_EJN_RR/Script task/ISP_MoBi_sequence.m

function [forces]=ISP_MoBi_sequence(contraction_task, data_subject, volume, forces, bl)

% the script is identical to ISP_MoBi_sequence_MEP with the exception of no
% force estimation and only MEP blocks (so there are only TEP blocks).
% refer to the ISP_MoBi_sequence_MEP for comments

max_force_left = forces.max_force_left;
max_force_right = forces.max_force_right;

cd 'C:\Users\neuro\Desktop\script_mobi_da_commentare'

sca;
close all;
    

%%

% consider left hand state
switch contraction_task{1,2} % force as a proportion of the outer circle...
    
    
    case 'Contratta'
        
        LEFT = [0.2 0.4];
        istruzione_sx = 'Mantieni\nil cerchietto\nverde';
        
    case 'Rilassata'
       
        LEFT = [0 0.01];
        istruzione_sx = 'Rilassa'
        
end

% consider right hand state
switch contraction_task{1,3}
        
     
    case 'Contratta'
       
        RIGHT = [0.2 0.4];
        istruzione_dx = 'Mantieni\nil cerchietto\nverde';
        
    case 'Rilassata'
        
        RIGHT = [0.0 0.01];
        istruzione_dx = 'Rilassa'
        
end
%% specify trigger number
switch contraction_task{1,1}
    
    case 'Mono_AP'
        TMS_trigger = 3;        

    case 'Mono_PA'
        TMS_trigger = 5;
        
    case 'Mono_LM'
        TMS_trigger = 7;
        
    case 'Bi_PA_contracted'
        TMS_trigger = 160;
        
    case 'Bi_AP'
        TMS_trigger = 130;
        
    case 'Bi_PA'
        TMS_trigger = 150;
        
    case 'Bi_LM'
        TMS_trigger = 170;
        
end



%%
% as a proportion to y axis...
outer_dimension = 0.4;



inner_dimensionL = LEFT(1);
middle_dimensionL = LEFT(2);


inner_dimensionR = RIGHT(1);
middle_dimensionR = RIGHT(2);


inner_force_limit_propL = inner_dimensionL;
outer_force_limit_propL = middle_dimensionL;

inner_force_limit_propR = inner_dimensionR;
outer_force_limit_propR = middle_dimensionR;

outer_circle_color = [1 1 1];%[0 0 0];%
middle_circle_color = [0.5 0.5 0.5];
inner_circle_color = [0 0 0];
variable_circle_colorL = [0 1 0];
variable_circle_colorR = [0 1 0];
variable_circle_thickness = 5;

force_steps = 500;

num_trials = 40;

estimation_time = 10; %secs

time_x_avg = 0.5; % secs

%% DO you want to tinker with small screen?
tinker = 0;
HideCursor

%% SCREEN SETTING
[window, misure_schermo, screenNum, CenterX, CenterY, ifi] = MoBi_Screen_Settings_Brescia(tinker);
%MoBi_Screen_Settings_Brescia;

%proporzioni_schermo = misure_schermo(4)/misure_schermo(3);

%%
delete(instrfindall);
clear s

%Set up the serial port
s = serial('COM5'); 
set(s, 'BaudRate', 115200); % set BaudRate to 115200 (as in Arduino!!!!!)

% open it
fopen(s);
WaitSecs(2);
for d = 1:2
    MoBi_scrittura(s);
end

%%
[ifi_af, ifi_as, ifi_nf, ifi_ns] = MoBI_frames_Brescia(ifi, ifi);

[onesec_af, onesec_as, onesec_nf, onesec_ns] = MoBI_frames_Brescia(1, ifi);


%% parallel port init

ioObj = io64;
status = io64(ioObj);

address = hex2dec('DFB8'); 
io64(ioObj, address  ,0); 

%%

delay_after_TMS = 0.4;
TMS_extremes = [4.4 6.4]-delay_after_TMS; 

TMS_interval_tmp = (TMS_extremes(2) - TMS_extremes(1))*rand(num_trials,1)+TMS_extremes(1);

[TMS_int_af, TMS_int_as, TMS_int_nf, TMS_int_ns] = MoBI_frames_Brescia(TMS_interval_tmp, ifi);



%% the systems outputs a "-1/force" function
% --> set the max of the function to max_force and the min to 0
% in steps of 500 values of forces (this can be changed)

x = linspace(1,10,force_steps);

% produce the shape
funz_tmp = (-1./x)+1;

% the shape is morphed so that it goes from 0 to 1 and multuplied by
% max_force
funzL = (funz_tmp./(funz_tmp(end)))*max_force_left;
funzR = (funz_tmp./(funz_tmp(end)))*max_force_right;

% this is the linear function with range [0 max_force] which will be
% helpful afterwards to linearize the voltage read
linearizeL = linspace(0, max_force_left, force_steps);
linearizeR = linspace(0, max_force_right, force_steps);


%% SET ALL THE VISUALS on the LEFT

% proportion with respect to the entire screen
set_proportion_of_diameter_outer_circleL = outer_dimension;
prop_diameter_outer_circleL = set_proportion_of_diameter_outer_circleL;

% transform proportions to actual pixels --> we get dimaeter of outer
% circle in pixels
dimensions_outer_circleL = MoBi_prop2dim(misure_schermo, 0, prop_diameter_outer_circleL);

% same procedure for inner and middle circle calculated on the basis of the outer
% circle
prop_diameter_inner_circleL = inner_dimensionL*prop_diameter_outer_circleL;
dimensions_inner_circleL = MoBi_prop2dim(misure_schermo, 0, prop_diameter_inner_circleL);

prop_diameter_middle_circleL = middle_dimensionL*prop_diameter_outer_circleL;
dimensions_middle_circleL = MoBi_prop2dim(misure_schermo, 0, prop_diameter_middle_circleL);


%% generate a structure for the LEFT circle with the features of the circle as fields

% we have two objsect now...place the left one on the first quarter of the
% screen length, the other on the last quarter

first_quarter = 3*misure_schermo(3)/8;
last_quarter = 5*misure_schermo(3)/8;

% ...color
ObL.outer_circle.color = outer_circle_color;
% ...diameter
ObL.outer_circle.dimension = [0 0 dimensions_outer_circleL(2) dimensions_outer_circleL(2)]
% center position on the screen
baseRect_outer = [ObL.outer_circle.dimension];

% place in the first quarter
ObL.outer_circle.dimension = CenterRectOnPoint(baseRect_outer, first_quarter, misure_schermo(4)/2);


% same goes for the other circles
ObL.inner_circle.color = inner_circle_color;
ObL.inner_circle.dimension = [0 0 dimensions_inner_circleL(2) dimensions_inner_circleL(2)]
baseRect_inner = [ObL.inner_circle.dimension];

% place in the first quarter
ObL.inner_circle.dimension = CenterRectOnPoint(baseRect_inner, first_quarter, misure_schermo(4)/2);



ObL.middle_circle.color = middle_circle_color;
ObL.middle_circle.dimension = [0 0 dimensions_middle_circleL(2) dimensions_middle_circleL(2)]
baseRect_middle = [ObL.middle_circle.dimension];

% place in the first quarter
ObL.middle_circle.dimension = CenterRectOnPoint(baseRect_middle, first_quarter, misure_schermo(4)/2);


%% SET ALL THE VISUALS on the RIGHT

% proportion with respect to the entire screen
set_proportion_of_diameter_outer_circleR = outer_dimension;
prop_diameter_outer_circleR = [set_proportion_of_diameter_outer_circleR];

% transform proportions to actual pixels --> we get dimaeter of outer
% circle in pixels
dimensions_outer_circleR = MoBi_prop2dim(misure_schermo, 0, prop_diameter_outer_circleR);

% same procedure for inner and middle circle calculated on the basis of the outer
% circle
prop_diameter_inner_circleR = inner_dimensionR*prop_diameter_outer_circleR;
dimensions_inner_circleR = MoBi_prop2dim(misure_schermo, 0, prop_diameter_inner_circleR);

prop_diameter_middle_circleR = middle_dimensionR*prop_diameter_outer_circleR;
dimensions_middle_circleR = MoBi_prop2dim(misure_schermo, 0, prop_diameter_middle_circleR);




%% generate a structure for the RIGHT circle with the features of the circle as fields

% ...color
ObR.outer_circle.color = outer_circle_color;
% ...diameter
ObR.outer_circle.dimension = [0 0 dimensions_outer_circleR(2) dimensions_outer_circleR(2)];
% center position on the screen;
baseRect_outer = [ObR.outer_circle.dimension];

% place in the first quarter
ObR.outer_circle.dimension = CenterRectOnPoint(baseRect_outer, last_quarter, misure_schermo(4)/2);% da che cosa dipendono questi numeri???


% same goes for the other circles
ObR.inner_circle.color = inner_circle_color;
ObR.inner_circle.dimension = [0 0 dimensions_inner_circleR(2) dimensions_inner_circleR(2)]
baseRect_inner = [ObR.inner_circle.dimension];

% place in the last quarter
ObR.inner_circle.dimension = CenterRectOnPoint(baseRect_inner, last_quarter, misure_schermo(4)/2);

ObR.middle_circle.color = middle_circle_color;
ObR.middle_circle.dimension = [0 0 dimensions_middle_circleR(2) dimensions_middle_circleR(2)]
baseRect_middle = [ObR.middle_circle.dimension];

% place in the last quarter
ObR.middle_circle.dimension = CenterRectOnPoint(baseRect_middle, last_quarter, misure_schermo(4)/2);



%% we also have a black background. let's treat it as a structre as well.
Bk.color = [0 0 0];
Bk.dimension = misure_schermo;

%% resolution setting:
% every time participant presses, read values change. here we set the boundary values to which a variable circle will change its diameter based on the pressure produced

% create a vector from 0 to diameter of outer circle in steps of
% length(x)
diameter_values_nonscaled_tmp = linspace(0, dimensions_outer_circleL(2), length(x));


% in case participants press more than what they did in the max_force
% evaluation, values bigger that outer_circle diameter are added, in order
% not to get errors.
% It should not happen though because it would mean the max_force
% estimatimation was performed in a shitty way.
diameter_values_nonscaled = [diameter_values_nonscaled_tmp ...
    diameter_values_nonscaled_tmp(end)+[1:100].*diff(diameter_values_nonscaled_tmp(1:2))];






%% INSTRUCTIONS FOR the researcher
Screen('FillRect', window, Bk.color, Bk.dimension);
Screen('TextSize', window, 25);


        hor_alignement = round(misure_schermo(3)*0.5,0);
        ver_alignement = round(misure_schermo(4)*0.25,0);
        

TMS_cond = contraction_task{1,1};

DrawFormattedText(window,TMS_cond, hor_alignement,...
    ver_alignement, [1 1 1]);

clear hor_alignement ver_alignement 

testo_sx = contraction_task{1,2};
    
    
        hor_alignement = round(misure_schermo(3)*0.25,0);
        ver_alignement = round(misure_schermo(4)*0.75,0);
        
        
 DrawFormattedText(window,testo_sx, hor_alignement,...
    ver_alignement, [1 1 1]);
       
 clear hor_alignement ver_alignement 
 
 
 
 
 
testo_dx = contraction_task{1,3};
    
    
        hor_alignement = round(misure_schermo(3)*0.75,0);
        ver_alignement = round(misure_schermo(4)*0.75,0);
        
        
 DrawFormattedText(window,testo_dx, hor_alignement,...
    ver_alignement, [1 1 1]);
       
 clear hor_alignement ver_alignement 

[VBL]=Screen(window, 'Flip', ifi, 1);

% wait for keyboard press
WaitSecs(2)

%%
 while ~KbCheck
 
 end


%% start noise


[audiodata, infreq] = psychwavread('AirCool_Magstim_48000.wav');

noise_seconds  = 60*5; 

noise_short = audiodata(1:infreq*noise_seconds)';

pasound2 = PsychPortAudio('Open', []);

sound2 = [noise_short;  noise_short];

PsychPortAudio('Volume', pasound2, volume);

PsychPortAudio('FillBuffer', pasound2, sound2);

noise_ts = PsychPortAudio('Start',pasound2, 1, 1);



%% RUN TIME ACTUAL EXPERIMENT

Screen('FillRect', window, [0 0 0], misure_schermo);
[VBL]=Screen(window, 'Flip', ifi, 1);
tic
on_spot = 0;
for tr = 1:num_trials
    
    
    i = 0;
    while 1
        
        % read from serial port what arduino has written
        force_tmp = MoBi_scrittura(s);
        
        % split the 3 values that are read from the three pins in arduino
        force_tmp2 = (strsplit(force_tmp, '_'));
        
        % GET INFO ONLY FROM THE A0 PIN, which is the first read
        force_tmpL = str2double(force_tmp2{1});
        force_tmpR = str2double(force_tmp2{2});
        
        % force linearization.
        [linear_forceL  idxL] = MoBi_linearize_force(force_tmpL, linearizeL, funzL);
        [linear_forceR idxR] = MoBi_linearize_force(force_tmpR, linearizeR, funzR);
        
        %%
        diameter_valuesL = diameter_values_nonscaled(idxL);
        diameter_valuesR = diameter_values_nonscaled(idxR);
        
        if on_spot  == 0
            % draw left side circles in background
            ObL.variable_circle.color = variable_circle_colorL;
            ObL.variable_circle.dimension = [0 0 diameter_valuesL diameter_valuesL];
            baseRect_variable = [ObL.variable_circle.dimension];
            ObL.variable_circle.dimension = CenterRectOnPoint(baseRect_variable, first_quarter, misure_schermo(4)/2);
            
            Screen('FrameOval', window, ObL.outer_circle.color, ObL.outer_circle.dimension);
            Screen('FillOval', window, ObL.middle_circle.color, ObL.middle_circle.dimension);
           
            Screen('FillOval', window, ObL.inner_circle.color, ObL.inner_circle.dimension);
            Screen('FrameOval', window, ObL.variable_circle.color, ObL.variable_circle.dimension, variable_circle_thickness);
            
            % draw right side circles in background
            ObR.variable_circle.color = variable_circle_colorR;
            ObR.variable_circle.dimension = [0 0 diameter_valuesR diameter_valuesR];
            baseRect_variable = [ObR.variable_circle.dimension];
            ObR.variable_circle.dimension = CenterRectOnPoint(baseRect_variable, last_quarter, misure_schermo(4)/2);
            
            Screen('FrameOval', window, ObR.outer_circle.color, ObR.outer_circle.dimension);
            Screen('FillOval', window, ObR.middle_circle.color, ObR.middle_circle.dimension);
          
            Screen('FillOval', window, ObR.inner_circle.color, ObR.inner_circle.dimension);
            Screen('FrameOval', window, ObR.variable_circle.color, ObR.variable_circle.dimension, variable_circle_thickness);
            
            
            Screen('TextSize', window, 80);
            DrawFormattedText(window, '+', 'center','center', [1 1 1]);
        else
            Screen('FillRect', window, [0 0 0], misure_schermo);
            Screen('TextSize', window, 80);
            DrawFormattedText(window, '+', 'center','center', [1 1 1]);
        end
        
        
        % flip
        [VBL] = Screen(window, 'Flip', VBL+ifi_as);
        
        sprintf( '%f_%f_%f____%f_%f_%f', inner_force_limit_propL*max_force_left, linear_forceL, outer_force_limit_propL*max_force_left,...
            inner_force_limit_propR*max_force_right, linear_forceR, outer_force_limit_propR*max_force_right)
        
        %% check force range for TMS
        if (linear_forceL >= inner_force_limit_propL*max_force_left) && (linear_forceL <= outer_force_limit_propL*max_force_left)...
                && (linear_forceR >= inner_force_limit_propR*max_force_right) && (linear_forceR <= outer_force_limit_propR*max_force_right)
            
            i= i+1;
            
      
            on_spot = 1;
            Screen('FillRect', window, [0 0 0], misure_schermo);
            Screen('TextSize', window, 80);
            DrawFormattedText(window, '+', 'center','center', [1 1 1]);
           
            
        else % ... if force is out of range
            i = 0;
            on_spot = 0;
            
            
            % change colors of the circle that is out
            if (linear_forceL <= inner_force_limit_propL*max_force_left) || (linear_forceL >= outer_force_limit_propL*max_force_left)...
                    
            variable_circle_colorL = [1 0 0];
            else
                variable_circle_colorL = [0 1 0];
            end
            
            if   (linear_forceR <= inner_force_limit_propR*max_force_right) || (linear_forceR >= outer_force_limit_propR*max_force_right)
                
                variable_circle_colorR = [1 0 0];
            else
                variable_circle_colorR = [0 1 0];
            end
        end
        
        
        
        
        % in case i is equal or greater than than the frames to be waited
        % for TMS to be delivered, then deliver TMS
        if i >= TMS_int_nf(tr)
            
            can_i_trigger = 1;
            
            % function implementing also trigger value
            MoBi_Trigger(ioObj,address,TMS_trigger, can_i_trigger);
            
            can_i_trigger = 0;
            
            TR.TMS_timing(tr) = VBL;
            TR.i(tr) = i;
            TR.ns(tr) =  TMS_int_ns(tr);
            TR.nf(tr) =  TMS_int_nf(tr);
            TR.tictoc(tr) = toc;
            disp(strcat('TMS', '_', num2str(tr)))
            
          
            WaitSecs(delay_after_TMS)
            
            % break the while loop and start another trial
            break
        end
        
        
        
        
    end
    
    
    
    
end

sca

% forces = struct;
% forces.max_force_left = max_force_left; 
% forces.max_force_right = max_force_right;
% forces.sbj = sbj;
% forces.order = ordine 
% forces.block = block;
% forces.within_ordine = row_tabella;
% forces.session = blocco;

PsychPortAudio('Stop', pasound2,0);   
PsychPortAudio('Close');
clear audiodata sound2 noise_short pasound2 sound2

save(data_subject)

end