2021_Aswendt_GFAP_PT_4wks/README.md

2021_Aswendt_GFAP_PT_4wks

Longitudinal MRI (T2-weighted and rs-fMRI) of GFAP-/-/Vim-/- and WT mice; 6 time points over 4 weeks post photothrombotic stroke.

Files:

• MRI_raw_data - contains all raw data in Bruker 2dseq format and the original Bruker folder structure
• MRI_proc_data - contains all data processed with the AIDAmri pipeline. Processing steps: 1) convert Bruker to NIfTI-1 data format, 2) image re-orientation, bias-field correction, brain extraction, 3) region-of-interest segmentation (i.e. stroke masks), 4) registration with the Allen Mouse Brain Atlas (CCFv3), and 5) functional connectivity analysis using AIDAconnect.

Authors:

Markus Aswendt, Olivia Käsgen, Frederique Wieters, Felix Schmitt, Niklas Pallast

Publication:

Aswendt et al. Prog Neurobiol 2022 https://doi.org/10.1016/j.pneurobio.2021.102199