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Paul Pfeiffer 1 year ago
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      README.md

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README.md

@@ -5,11 +5,11 @@ This data repository holds the dynamic clamp recordings and analysis scripts to
 ## Overview
 
 ### Recordings 
-Cells were patchclamped and the dynamic clamp was used to emulate the presence of multiple clusters of cooperative ion channels. in the membrane.Succesive current pulses were used to test for persistent activity and graded persistent activity. 
+Cells were recorded intracellularly and the dynamic clamp was used to emulate the presence of multiple clusters of cooperative ion channels in the membrane. Succesive current pulses were used to test for persistent activity and graded persistent activity. 
 
 ### Analysis
 
-The stimulation protocols were categorized according to the number of pulses and whether the pulses were de- or hyperpolarizing. Then recordings with increasing (respectively decreasing) levels of persistent activity were labelled as successful trials. 
+The stimulation protocols were categorized according to the number of pulses and whether the pulses were de- or hyperpolarizing. Then the firing rate between pulses was estimated to test whether the cells were persistenly active and whether the persistent firing increased (respectively decreased) with the number of applied pulses. 
 
 ### Structure of the repository
 The repository is structured as follows
@@ -23,12 +23,10 @@ The repository is structured as follows
 Tested in Linux
 
 1. Install python dependencies e.g. via conda
-   
    ```bash
    conda env create -f environment.yml 
    ```
 2. Run analysis and generate the report
-
    ```bash
    make all 
    ```