Summary

Anatomical

Anatomical Conformation

Brain mask and brain tissue segmentation of the T1w

This panel shows the template T1-weighted image (if several T1w images were found), with contours delineating the detected brain mask and brain tissue segmentations.


filename:sub-04/figures/sub-04_seg_brainmask.svg
Get figure file: sub-04/figures/sub-04_seg_brainmask.svg

T1 to MNI registration

Nonlinear mapping of the T1w image into MNI space. Hover on the panel with the mouse to transition between both spaces.


filename:sub-04/figures/sub-04_t1_2_mni.svg
Get figure file: sub-04/figures/sub-04_t1_2_mni.svg

Functional

Summary

Note on orientation: qform matrix overwritten

The qform has been copied from sform.

Susceptibility distortion correction

Results of performing susceptibility distortion correction (SDC) on the EPI


filename:sub-04/figures/sub-04_task-sherlockPart1_sdc_syn.svg
Get figure file: sub-04/figures/sub-04_task-sherlockPart1_sdc_syn.svg

ROIs in BOLD space

Brain mask calculated on the BOLD signal (red contour), along with the masks used for a/tCompCor.
The aCompCor mask (magenta contour) is a conservative CSF and white-matter mask for extracting physiological and movement confounds.
The fCompCor mask (blue contour) contains the top 5% most variable voxels within a heavily-eroded brain-mask.


filename:sub-04/figures/sub-04_task-sherlockPart1_rois.svg
Get figure file: sub-04/figures/sub-04_task-sherlockPart1_rois.svg

EPI to T1 registration

FSL flirt was used to generate transformations from EPI-space to T1w-space - The white matter mask calculated with FSL fast (brain tissue segmentation) was used for BBR


filename:sub-04/figures/sub-04_task-sherlockPart1_flirtbbr.svg
Get figure file: sub-04/figures/sub-04_task-sherlockPart1_flirtbbr.svg

BOLD Summary

Summary statistics are plotted, which may reveal trends or artifacts in the BOLD data. Global signals calculated within the whole-brain (GS), within the white-matter (WM) and within cerebro-spinal fluid (CSF) show the mean BOLD signal in their corresponding masks. DVARS and FD show the standardized DVARS and framewise-displacement measures for each time point.
A carpet plot shows the time series for all voxels within the brain mask. Voxels are grouped into cortical (blue), and subcortical (orange) gray matter, cerebellum (green) and white matter and CSF (red), indicated by the color map on the left-hand side.


filename:sub-04/figures/sub-04_task-sherlockPart1_carpetplot.svg
Get figure file: sub-04/figures/sub-04_task-sherlockPart1_carpetplot.svg

About

Methods

We kindly ask to report results preprocessed with fMRIPrep using the following boilerplate

Results included in this manuscript come from preprocessing performed using fMRIPprep 1.2.6-1 (Esteban, Markiewicz, et al. (2018); Esteban, Blair, et al. (2018); RRID:SCR_016216), which is based on Nipype 1.1.7 (Gorgolewski et al. (2011); Gorgolewski et al. (2018); RRID:SCR_002502).

Anatomical data preprocessing

The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU) using N4BiasFieldCorrection (Tustison et al. 2010, ANTs 2.2.0), and used as T1w-reference throughout the workflow. The T1w-reference was then skull-stripped using antsBrainExtraction.sh (ANTs 2.2.0), using OASIS as target template. Spatial normalization to the ICBM 152 Nonlinear Asymmetrical template version 2009c (Fonov et al. 2009, RRID:SCR_008796) was performed through nonlinear registration with antsRegistration (ANTs 2.2.0, RRID:SCR_004757, Avants et al. 2008), using brain-extracted versions of both T1w volume and template. Brain tissue segmentation of cerebrospinal fluid (CSF), white-matter (WM) and gray-matter (GM) was performed on the brain-extracted T1w using fast (FSL 5.0.9, RRID:SCR_002823, Zhang, Brady, and Smith 2001).

Functional data preprocessing

For each of the 1 BOLD runs found per subject (across all tasks and sessions), the following preprocessing was performed. First, a reference volume and its skull-stripped version were generated using a custom methodology of fMRIPrep. A deformation field to correct for susceptibility distortions was estimated based on fMRIPrep’s fieldmap-less approach. The deformation field is that resulting from co-registering the BOLD reference to the same-subject T1w-reference with its intensity inverted (Wang et al. 2017; Huntenburg 2014). Registration is performed with antsRegistration (ANTs 2.2.0), and the process regularized by constraining deformation to be nonzero only along the phase-encoding direction, and modulated with an average fieldmap template (Treiber et al. 2016). Based on the estimated susceptibility distortion, an unwarped BOLD reference was calculated for a more accurate co-registration with the anatomical reference. The BOLD reference was then co-registered to the T1w reference using flirt (FSL 5.0.9, Jenkinson and Smith 2001) with the boundary-based registration (Greve and Fischl 2009) cost-function. Co-registration was configured with nine degrees of freedom to account for distortions remaining in the BOLD reference. Head-motion parameters with respect to the BOLD reference (transformation matrices, and six corresponding rotation and translation parameters) are estimated before any spatiotemporal filtering using mcflirt (FSL 5.0.9, Jenkinson et al. 2002). The BOLD time-series (including slice-timing correction when applied) were resampled onto their original, native space by applying a single, composite transform to correct for head-motion and susceptibility distortions. These resampled BOLD time-series will be referred to as preprocessed BOLD in original space, or just preprocessed BOLD. The BOLD time-series were resampled to MNI152NLin2009cAsym standard space, generating a preprocessed BOLD run in MNI152NLin2009cAsym space. First, a reference volume and its skull-stripped version were generated using a custom methodology of fMRIPrep. Several confounding time-series were calculated based on the preprocessed BOLD: framewise displacement (FD), DVARS and three region-wise global signals. FD and DVARS are calculated for each functional run, both using their implementations in Nipype (following the definitions by Power et al. 2014). The three global signals are extracted within the CSF, the WM, and the whole-brain masks. Additionally, a set of physiological regressors were extracted to allow for component-based noise correction (CompCor, Behzadi et al. 2007). Principal components are estimated after high-pass filtering the preprocessed BOLD time-series (using a discrete cosine filter with 128s cut-off) for the two CompCor variants: temporal (tCompCor) and anatomical (aCompCor). Six tCompCor components are then calculated from the top 5% variable voxels within a mask covering the subcortical regions. This subcortical mask is obtained by heavily eroding the brain mask, which ensures it does not include cortical GM regions. For aCompCor, six components are calculated within the intersection of the aforementioned mask and the union of CSF and WM masks calculated in T1w space, after their projection to the native space of each functional run (using the inverse BOLD-to-T1w transformation). The head-motion estimates calculated in the correction step were also placed within the corresponding confounds file. All resamplings can be performed with a single interpolation step by composing all the pertinent transformations (i.e. head-motion transform matrices, susceptibility distortion correction when available, and co-registrations to anatomical and template spaces). Gridded (volumetric) resamplings were performed using antsApplyTransforms (ANTs), configured with Lanczos interpolation to minimize the smoothing effects of other kernels (Lanczos 1964). Non-gridded (surface) resamplings were performed using mri_vol2surf (FreeSurfer).

Many internal operations of fMRIPrep use Nilearn 0.5.0 (Abraham et al. 2014, RRID:SCR_001362), mostly within the functional processing workflow. For more details of the pipeline, see the section corresponding to workflows in fMRIPrep’s documentation.

References

Abraham, Alexandre, Fabian Pedregosa, Michael Eickenberg, Philippe Gervais, Andreas Mueller, Jean Kossaifi, Alexandre Gramfort, Bertrand Thirion, and Gael Varoquaux. 2014. “Machine Learning for Neuroimaging with Scikit-Learn.” Frontiers in Neuroinformatics 8. https://doi.org/10.3389/fninf.2014.00014.

Avants, B.B., C.L. Epstein, M. Grossman, and J.C. Gee. 2008. “Symmetric Diffeomorphic Image Registration with Cross-Correlation: Evaluating Automated Labeling of Elderly and Neurodegenerative Brain.” Medical Image Analysis 12 (1): 26–41. https://doi.org/10.1016/j.media.2007.06.004.

Behzadi, Yashar, Khaled Restom, Joy Liau, and Thomas T. Liu. 2007. “A Component Based Noise Correction Method (CompCor) for BOLD and Perfusion Based fMRI.” NeuroImage 37 (1): 90–101. https://doi.org/10.1016/j.neuroimage.2007.04.042.

Esteban, Oscar, Ross Blair, Christopher J. Markiewicz, Shoshana L. Berleant, Craig Moodie, Feilong Ma, Ayse Ilkay Isik, et al. 2018. “FMRIPrep.” Software. Zenodo. https://doi.org/10.5281/zenodo.852659.

Esteban, Oscar, Christopher Markiewicz, Ross W Blair, Craig Moodie, Ayse Ilkay Isik, Asier Erramuzpe Aliaga, James Kent, et al. 2018. “fMRIPrep: A Robust Preprocessing Pipeline for Functional MRI.” Nature Methods. https://doi.org/10.1038/s41592-018-0235-4.

Fonov, VS, AC Evans, RC McKinstry, CR Almli, and DL Collins. 2009. “Unbiased Nonlinear Average Age-Appropriate Brain Templates from Birth to Adulthood.” NeuroImage, Organization for human brain mapping 2009 annual meeting, 47, Supplement 1: S102. https://doi.org/10.1016/S1053-8119(09)70884-5.

Gorgolewski, K., C. D. Burns, C. Madison, D. Clark, Y. O. Halchenko, M. L. Waskom, and S. Ghosh. 2011. “Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python.” Frontiers in Neuroinformatics 5: 13. https://doi.org/10.3389/fninf.2011.00013.

Gorgolewski, Krzysztof J., Oscar Esteban, Christopher J. Markiewicz, Erik Ziegler, David Gage Ellis, Michael Philipp Notter, Dorota Jarecka, et al. 2018. “Nipype.” Software. Zenodo. https://doi.org/10.5281/zenodo.596855.

Greve, Douglas N, and Bruce Fischl. 2009. “Accurate and Robust Brain Image Alignment Using Boundary-Based Registration.” NeuroImage 48 (1): 63–72. https://doi.org/10.1016/j.neuroimage.2009.06.060.

Huntenburg, Julia M. 2014. “Evaluating Nonlinear Coregistration of BOLD EPI and T1w Images.” Master’s Thesis, Berlin: Freie Universität. http://hdl.handle.net/11858/00-001M-0000-002B-1CB5-A.

Jenkinson, Mark, Peter Bannister, Michael Brady, and Stephen Smith. 2002. “Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images.” NeuroImage 17 (2): 825–41. https://doi.org/10.1006/nimg.2002.1132.

Jenkinson, Mark, and Stephen Smith. 2001. “A Global Optimisation Method for Robust Affine Registration of Brain Images.” Medical Image Analysis 5 (2): 143–56. https://doi.org/10.1016/S1361-8415(01)00036-6.

Lanczos, C. 1964. “Evaluation of Noisy Data.” Journal of the Society for Industrial and Applied Mathematics Series B Numerical Analysis 1 (1): 76–85. https://doi.org/10.1137/0701007.

Power, Jonathan D., Anish Mitra, Timothy O. Laumann, Abraham Z. Snyder, Bradley L. Schlaggar, and Steven E. Petersen. 2014. “Methods to Detect, Characterize, and Remove Motion Artifact in Resting State fMRI.” NeuroImage 84 (Supplement C): 320–41. https://doi.org/10.1016/j.neuroimage.2013.08.048.

Treiber, Jeffrey Mark, Nathan S. White, Tyler Christian Steed, Hauke Bartsch, Dominic Holland, Nikdokht Farid, Carrie R. McDonald, Bob S. Carter, Anders Martin Dale, and Clark C. Chen. 2016. “Characterization and Correction of Geometric Distortions in 814 Diffusion Weighted Images.” PLOS ONE 11 (3): e0152472. https://doi.org/10.1371/journal.pone.0152472.

Tustison, N. J., B. B. Avants, P. A. Cook, Y. Zheng, A. Egan, P. A. Yushkevich, and J. C. Gee. 2010. “N4ITK: Improved N3 Bias Correction.” IEEE Transactions on Medical Imaging 29 (6): 1310–20. https://doi.org/10.1109/TMI.2010.2046908.

Wang, Sijia, Daniel J. Peterson, J. C. Gatenby, Wenbin Li, Thomas J. Grabowski, and Tara M. Madhyastha. 2017. “Evaluation of Field Map and Nonlinear Registration Methods for Correction of Susceptibility Artifacts in Diffusion MRI.” Frontiers in Neuroinformatics 11. https://doi.org/10.3389/fninf.2017.00017.

Zhang, Y., M. Brady, and S. Smith. 2001. “Segmentation of Brain MR Images Through a Hidden Markov Random Field Model and the Expectation-Maximization Algorithm.” IEEE Transactions on Medical Imaging 20 (1): 45–57. https://doi.org/10.1109/42.906424.

Results included in this manuscript come from preprocessing
performed using *fMRIPprep* 1.2.6-1
(@fmriprep1; @fmriprep2; RRID:SCR_016216),
which is based on *Nipype* 1.1.7
(@nipype1; @nipype2; RRID:SCR_002502).

Anatomical data preprocessing

: The T1-weighted (T1w) image was corrected for intensity non-uniformity (INU)
using `N4BiasFieldCorrection` [@n4, ANTs 2.2.0],
and used as T1w-reference throughout the workflow.
The T1w-reference was then skull-stripped using `antsBrainExtraction.sh`
(ANTs 2.2.0), using OASIS as target template.
Spatial normalization to the ICBM 152 Nonlinear Asymmetrical
template version 2009c [@mni, RRID:SCR_008796] was performed
through nonlinear registration with `antsRegistration`
[ANTs 2.2.0, RRID:SCR_004757, @ants], using
brain-extracted versions of both T1w volume and template.
Brain tissue segmentation of cerebrospinal fluid (CSF),
white-matter (WM) and gray-matter (GM) was performed on
the brain-extracted T1w using `fast` [FSL 5.0.9, RRID:SCR_002823,
@fsl_fast].


Functional data preprocessing

: For each of the 1 BOLD runs found per subject (across all
tasks and sessions), the following preprocessing was performed.
First, a reference volume and its skull-stripped version were generated
using a custom methodology of *fMRIPrep*.
A deformation field to correct for susceptibility distortions was estimated
based on *fMRIPrep*'s *fieldmap-less* approach.
The deformation field is that resulting from co-registering the BOLD reference
to the same-subject T1w-reference with its intensity inverted [@fieldmapless1;
@fieldmapless2].
Registration is performed with `antsRegistration` (ANTs 2.2.0), and
the process regularized by constraining deformation to be nonzero only
along the phase-encoding direction, and modulated with an average fieldmap
template [@fieldmapless3].
Based on the estimated susceptibility distortion, an
unwarped BOLD reference was calculated for a more accurate
co-registration with the anatomical reference.
The BOLD reference was then co-registered to the T1w reference using
`flirt` [FSL 5.0.9, @flirt] with the boundary-based registration [@bbr]
cost-function.
Co-registration was configured with nine degrees of freedom to account
for distortions remaining in the BOLD reference.
Head-motion parameters with respect to the BOLD reference
(transformation matrices, and six corresponding rotation and translation
parameters) are estimated before any spatiotemporal filtering using
`mcflirt` [FSL 5.0.9, @mcflirt].
The BOLD time-series (including slice-timing correction when applied)
were resampled onto their original, native space by applying
a single, composite transform to correct for head-motion and
susceptibility distortions.
These resampled BOLD time-series will be referred to as *preprocessed
BOLD in original space*, or just *preprocessed BOLD*.
The BOLD time-series were resampled to MNI152NLin2009cAsym standard space,
generating a *preprocessed BOLD run in MNI152NLin2009cAsym space*.
First, a reference volume and its skull-stripped version were generated
using a custom methodology of *fMRIPrep*.
Several confounding time-series were calculated based on the
*preprocessed BOLD*: framewise displacement (FD), DVARS and
three region-wise global signals.
FD and DVARS are calculated for each functional run, both using their
implementations in *Nipype* [following the definitions by @power_fd_dvars].
The three global signals are extracted within the CSF, the WM, and
the whole-brain masks.
Additionally, a set of physiological regressors were extracted to
allow for component-based noise correction [*CompCor*, @compcor].
Principal components are estimated after high-pass filtering the
*preprocessed BOLD* time-series (using a discrete cosine filter with
128s cut-off) for the two *CompCor* variants: temporal (tCompCor)
and anatomical (aCompCor).
Six tCompCor components are then calculated from the top 5% variable
voxels within a mask covering the subcortical regions.
This subcortical mask is obtained by heavily eroding the brain mask,
which ensures it does not include cortical GM regions.
For aCompCor, six components are calculated within the intersection of
the aforementioned mask and the union of CSF and WM masks calculated
in T1w space, after their projection to the native space of each
functional run (using the inverse BOLD-to-T1w transformation).
The head-motion estimates calculated in the correction step were also
placed within the corresponding confounds file.
All resamplings can be performed with *a single interpolation
step* by composing all the pertinent transformations (i.e. head-motion
transform matrices, susceptibility distortion correction when available,
and co-registrations to anatomical and template spaces).
Gridded (volumetric) resamplings were performed using `antsApplyTransforms` (ANTs),
configured with Lanczos interpolation to minimize the smoothing
effects of other kernels [@lanczos].
Non-gridded (surface) resamplings were performed using `mri_vol2surf`
(FreeSurfer).


Many internal operations of *fMRIPrep* use
*Nilearn* 0.5.0 [@nilearn, RRID:SCR_001362],
mostly within the functional processing workflow.
For more details of the pipeline, see [the section corresponding
to workflows in *fMRIPrep*'s documentation](https://fmriprep.readthedocs.io/en/latest/workflows.html "FMRIPrep's documentation").


### References

Results included in this manuscript come from preprocessing performed
using \emph{fMRIPprep} 1.2.6-1 (\citet{fmriprep1}; \citet{fmriprep2};
RRID:SCR\_016216), which is based on \emph{Nipype} 1.1.7
(\citet{nipype1}; \citet{nipype2}; RRID:SCR\_002502).

\begin{description}
\item[Anatomical data preprocessing]
The T1-weighted (T1w) image was corrected for intensity non-uniformity
(INU) using \texttt{N4BiasFieldCorrection} \citep[ANTs 2.2.0]{n4}, and
used as T1w-reference throughout the workflow. The T1w-reference was
then skull-stripped using \texttt{antsBrainExtraction.sh} (ANTs 2.2.0),
using OASIS as target template. Spatial normalization to the ICBM 152
Nonlinear Asymmetrical template version 2009c
\citep[RRID:SCR\_008796]{mni} was performed through nonlinear
registration with \texttt{antsRegistration} \citep[ANTs 2.2.0,
RRID:SCR\_004757,][]{ants}, using brain-extracted versions of both T1w
volume and template. Brain tissue segmentation of cerebrospinal fluid
(CSF), white-matter (WM) and gray-matter (GM) was performed on the
brain-extracted T1w using \texttt{fast} \citep[FSL 5.0.9,
RRID:SCR\_002823,][]{fsl_fast}.
\item[Functional data preprocessing]
For each of the 1 BOLD runs found per subject (across all tasks and
sessions), the following preprocessing was performed. First, a reference
volume and its skull-stripped version were generated using a custom
methodology of \emph{fMRIPrep}. A deformation field to correct for
susceptibility distortions was estimated based on \emph{fMRIPrep}'s
\emph{fieldmap-less} approach. The deformation field is that resulting
from co-registering the BOLD reference to the same-subject T1w-reference
with its intensity inverted \citep{fieldmapless1, fieldmapless2}.
Registration is performed with \texttt{antsRegistration} (ANTs 2.2.0),
and the process regularized by constraining deformation to be nonzero
only along the phase-encoding direction, and modulated with an average
fieldmap template \citep{fieldmapless3}. Based on the estimated
susceptibility distortion, an unwarped BOLD reference was calculated for
a more accurate co-registration with the anatomical reference. The BOLD
reference was then co-registered to the T1w reference using
\texttt{flirt} \citep[FSL 5.0.9,][]{flirt} with the boundary-based
registration \citep{bbr} cost-function. Co-registration was configured
with nine degrees of freedom to account for distortions remaining in the
BOLD reference. Head-motion parameters with respect to the BOLD
reference (transformation matrices, and six corresponding rotation and
translation parameters) are estimated before any spatiotemporal
filtering using \texttt{mcflirt} \citep[FSL 5.0.9,][]{mcflirt}. The BOLD
time-series (including slice-timing correction when applied) were
resampled onto their original, native space by applying a single,
composite transform to correct for head-motion and susceptibility
distortions. These resampled BOLD time-series will be referred to as
\emph{preprocessed BOLD in original space}, or just \emph{preprocessed
BOLD}. The BOLD time-series were resampled to MNI152NLin2009cAsym
standard space, generating a \emph{preprocessed BOLD run in
MNI152NLin2009cAsym space}. First, a reference volume and its
skull-stripped version were generated using a custom methodology of
\emph{fMRIPrep}. Several confounding time-series were calculated based
on the \emph{preprocessed BOLD}: framewise displacement (FD), DVARS and
three region-wise global signals. FD and DVARS are calculated for each
functional run, both using their implementations in \emph{Nipype}
\citep[following the definitions by][]{power_fd_dvars}. The three global
signals are extracted within the CSF, the WM, and the whole-brain masks.
Additionally, a set of physiological regressors were extracted to allow
for component-based noise correction \citep[\emph{CompCor},][]{compcor}.
Principal components are estimated after high-pass filtering the
\emph{preprocessed BOLD} time-series (using a discrete cosine filter
with 128s cut-off) for the two \emph{CompCor} variants: temporal
(tCompCor) and anatomical (aCompCor). Six tCompCor components are then
calculated from the top 5\% variable voxels within a mask covering the
subcortical regions. This subcortical mask is obtained by heavily
eroding the brain mask, which ensures it does not include cortical GM
regions. For aCompCor, six components are calculated within the
intersection of the aforementioned mask and the union of CSF and WM
masks calculated in T1w space, after their projection to the native
space of each functional run (using the inverse BOLD-to-T1w
transformation). The head-motion estimates calculated in the correction
step were also placed within the corresponding confounds file. All
resamplings can be performed with \emph{a single interpolation step} by
composing all the pertinent transformations (i.e.~head-motion transform
matrices, susceptibility distortion correction when available, and
co-registrations to anatomical and template spaces). Gridded
(volumetric) resamplings were performed using
\texttt{antsApplyTransforms} (ANTs), configured with Lanczos
interpolation to minimize the smoothing effects of other kernels
\citep{lanczos}. Non-gridded (surface) resamplings were performed using
\texttt{mri\_vol2surf} (FreeSurfer).
\end{description}

Many internal operations of \emph{fMRIPrep} use \emph{Nilearn} 0.5.0
\citep[RRID:SCR\_001362]{nilearn}, mostly within the functional
processing workflow. For more details of the pipeline, see
\href{https://fmriprep.readthedocs.io/en/latest/workflows.html}{the
section corresponding to workflows in \emph{fMRIPrep}'s documentation}.

\hypertarget{references}{%
\subsubsection{References}\label{references}}

\bibliography{/usr/local/miniconda/lib/python3.7/site-packages/fmriprep/data/boilerplate.bib}

Bibliography

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    author = {Esteban, Oscar and Markiewicz, Christopher and Blair, Ross W and Moodie, Craig and Isik, Ayse Ilkay and Erramuzpe Aliaga, Asier and Kent, James and Goncalves, Mathias and DuPre, Elizabeth and Snyder, Madeleine and Oya, Hiroyuki and Ghosh, Satrajit and Wright, Jessey and Durnez, Joke and Poldrack, Russell and Gorgolewski, Krzysztof Jacek},
    title = {{fMRIPrep}: a robust preprocessing pipeline for functional {MRI}},
    year = {2018},
    doi = {10.1038/s41592-018-0235-4},
    journal = {Nature Methods}
}

@article{fmriprep2,
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    title = {fMRIPrep},
    year = 2018,
    doi = {10.5281/zenodo.852659},
    publisher = {Zenodo},
    journal = {Software}
}

@article{nipype1,
    author = {Gorgolewski, K. and Burns, C. D. and Madison, C. and Clark, D. and Halchenko, Y. O. and Waskom, M. L. and Ghosh, S.},
    doi = {10.3389/fninf.2011.00013},
    journal = {Frontiers in Neuroinformatics},
    pages = 13,
    shorttitle = {Nipype},
    title = {Nipype: a flexible, lightweight and extensible neuroimaging data processing framework in Python},
    volume = 5,
    year = 2011
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Alternatively, an interactive boilerplate generator is available in the documentation website.

Errors