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# Readme
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-
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This repository contains data resources accompanying the article:
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[C. Ledig][cledig], [A. Schuh][schuschu], R. Guerrero, [R. Heckemann][rheckemann], [D. Rueckert][drueckert]
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"Structural brain imaging in Alzheimer's disease and mild cognitive impairment: biomarker analysis and shared morphometry database", Scientific Reports, 2018.
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-This work was done in the [BioMedIA][biomedia] group at
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-Imperial College London, UK.
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+In this article, we employed a recently validated method (MALPEM) for robust cross-sectional and longitudinal segmentation of MR brain images from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) cohort. Specifically, we segmented 5074 MR brain images into 138 anatomical regions and extracted time-point specific structural volumes and volume change during follow-up intervals of 12 or 24 months.
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+The work was done in the [BioMedIA][biomedia] group at Imperial College London, UK.
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[cledig]: http://www.christianledig.com
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[biomedia]: http://biomedic.doc.ic.ac.uk
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@@ -14,6 +14,7 @@ Imperial College London, UK.
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[rheckemann]: https://www.soundray.org
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[drueckert]: http://wp.doc.ic.ac.uk/dr/
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## Citation
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Please cite as:
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@article{Ledig2018,
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@@ -26,7 +27,7 @@ Please cite as:
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## File Description
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-**Processed Images**
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+**Processed Images from the ADNI cohort**
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- List of all 5074 images (includes baseline and follow up images) [[ADNI_MALPEM_all_5074.csv]](https://web.gin.g-node.org/ledigchr/MALPEM_ADNI_data/src/master/ADNI_MALPEM_all_5074.csv)
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- List of 1069 baseline images used for analysis [[ADNI_MALPEM_baseline_1069.csv]](https://web.gin.g-node.org/ledigchr/MALPEM_ADNI_data/src/master/ADNI_MALPEM_baseline_1069.csv)
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@@ -82,3 +83,8 @@ R. Heckemann, C. Ledig, K. R. Gray, P. Aljabar, D. Rueckert, J. V. Hajnal, and A
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"Brain extraction using label propagation and group agreement: pincram",
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PLoS ONE, 10(7), pp. e0129211, 2015.
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+## Acknowledgements
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+Data used in preparation of this article were obtained from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) database [[link]][adni]. As such, the investigators within the ADNI contributed to the design and implementation of ADNI and/or provided data but did not participate in analysis or writing of this report. A complete listing of ADNI investigators can be found at: [[link]][adni_ack]
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+[adni]: adni.loni.usc.edu
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+[adni_ack]: http://adni.loni.usc.edu/wp-content/uploads/how_to_apply/ADNI_Acknowledgement_List.pdf
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