RSC_HPC/README.md

RSC_HPC

These data were collected by Dun Mao in the laboratory of Bruce L. McNaughton at the Canadian Centre for Behavioural Neuroscience, University of Lethbridge. These data accompany the following publication:

Hippocampus-dependent emergence of spatial sequence coding in retrosplenial cortex

Dun Mao, Adam R. Neumann, Jianjun Sun, Vincent Bonin, Majid H. Mohajerani, and Bruce L. McNaughton

www.pnas.org/cgi/doi/10.1073/pnas.1803224115

If you wish to use the data in any form or want to collaborate, please get in touch at: zjumao@gmail.com (Dun Mao) or bruce.mcnaughton@uleth.ca (Bruce McNaughton)

Data description:

Calcium fluorescence signals of hundreds of simultaneously imaged neurons in mouse retrosplenial cortex during a locomotion task (running on a linear treadmill track with head-fixed), from different experimental groups of animals: control mice, mice with unilateral hippocampus lesion (uni), and mice with bilateral hippocampus lesions (bi).

Each element in the .mat cell array corresponds to data from one animal with the suffix indicating experimental group (n = 5 mice in each group).

Data structure explained below:

behavior.

ts: timestamp in second

pos_norm: normalized position (0~1, circular) for each trial

trial: trial number

speed: movement speed, in cm/s

speed_raw: raw running speed, extracted directly from encoder pulses

pos_cum: cumulative position (cm) for the entire session

pos_raw: raw position (cm) for each trial

imaging:

ratio: dF/F (%), nSamples x nCells

deconv: deconvolved calcium signal (%), nSamples x nCells

tt: timestamp in second