# RSC_HPC These data were collected by Dun Mao in the laboratory of Bruce L. McNaughton at the Canadian Centre for Behavioural Neuroscience, University of Lethbridge. These data accompany the following publication: ### **Hippocampus-dependent emergence of spatial sequence coding in retrosplenial cortex** ### **Dun Mao, Adam R. Neumann, Jianjun Sun, Vincent Bonin, Majid H. Mohajerani, and Bruce L. McNaughton** www.pnas.org/cgi/doi/10.1073/pnas.1803224115 If you want to use the data in any form or want to collaborate, please get in touch at: zjumao@gmail.com (Dun Mao) or bruce.mcnaughton@uleth.ca (Bruce McNaughton) **Data description:** Calcium fluorescence signals of hundreds of simultaneously imaged neurons in mouse retrosplenial cortex during a virtual navigation task (running on a linear treadmill track with head-fixed), from different experimental groups of animals: control mice, mice with unilateral hippocampus lesion (uni), and mice with bilateral hippocampus lesions (bi). Each element in the cell array corresponds to data from one animal with the suffix indicating experimental group. data structure explained below: **behavior**. **ts**: time stamp in second **pos_norm**: normalized position (0~1, circular) for each trial **trial**: trial number **speed**: movement speed, in cm/s **speed_raw**: raw running speed, extracted directly from encoder pulses **pos_cum**: cumulative position (cm) for the entire session **pos_raw**: raw position (cm) for each trial **imaging:** **ratio**: dF/F (%), nSamples x nCells **deconv**: deconvolved calcium signal (%), nSamples x nCells **tt**: time stamp in second **avgstack**: mean stack image