# Metadata for DOI registration according to DataCite Metadata Schema 4.1. # For detailed schema description see https://doi.org/10.5438/0014 ## Required fields # The main researchers involved. Include digital identifier (e.g., ORCID) # if possible, including the prefix to indicate its type. authors: - firstname: "Michael" lastname: "Happ" affiliation: "MIT" id: "ORCID:0000-0001-6345-2272" # A title to describe the published resource. title: "A Predictive Circuit for Novelty Detection in Songbird Auditory Cortex" # Additional information about the resource, e.g., a brief abstract. description: | In order to make sense of complicated sensory landscapes, the brain privileges the processing of novel stimuli. Detecting novelty is therefore a fundamental problem for the brain to solve. And it turns out to be complicated, as stimuli can be completely novel, or just novel relative to certain certain contexts or expectations. To better understand how the brain detects both types of novelty, we studied an auditory region of the avian brain that performs both absolute and relative novelty detection. We introduce a predictive model, called the Agnotron, that is capable of performing both kinds of novelty detection with the same circuit mechanism. Armed with predictions made by the Agnotron, we perform experiments to confirm the existence of Agnotron- like circuitry in the brain. While we fail to find evidence that the various novelty signals in this brain area are produced by the same mechanism, we do find support for predictive circuitry for some novelty signals. We continue with an advanced investigation of one absolute novelty signal in particular, known as the Song-Specific Adaptation. After recapitulating classical results with state-of-the-art technology, we report novel phenomena that rule out predictive circuit mechanisms for the SSA. Taken together, our results suggest that predictive mechanisms can explain some novelty signals in the avian brain, but not the SSA, which seems to have a more simplistic feed-forward mechanism of generation. # Lit of keywords the resource should be associated with. # Give as many keywords as possible, to make the resource findable. keywords: - Neuroscience - Novelty - Prediction - Songbird - Audition - Error # License information for this resource. Please provide the license name and/or a link to the license. # Please add also a corresponding LICENSE file to the repository. license: name: "Creative Commons CC0 1.0 Public Domain Dedication" url: "https://creativecommons.org/publicdomain/zero/1.0/" references: - id: doi:tba reftype: "IsSupplementTo" citation: Happ, Michael Liu (March 1, 2023). A predictive circuit for novelty detection in Songbird Auditory Cortex. Massachusetts Institute of Technology, Cambridge, MA, USA. # Resource type. Default is Dataset, other possible values are Software, DataPaper, Image, Text. resourcetype: Dataset # Do not edit or remove the following line templateversion: 1.2