Longitudinal (4 wks) T2-weighted MRI and DTI of WT mice with cortical stroke (thromboembolic model) in C57BL/6 mice.

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README.md

WT_Thrombin_4wks_T2w_DTI

Longitudinal MRI including T2-weighted (T2w) and diffusion tensor imaging (DTI) WT mice with cortical stroke lesions induced by injection of thrombin and survival time of 4 weeks (4 wks).

Files:

  • File structure: Study > MRI_proc/raw_data > Group > Time point > Subject ID.
    • Time point (Baseline, post stroke days 1, 14, and 28)
    • Group (Stroke and Sham)
  • MRI_raw_data: - contains all raw data in Bruker 2dseq format and the original Bruker folder structure
  • MRI_proc_data: - contains all data processed with the AIDAmri_v1.1 pipeline. Processing steps: define stroke masks, convert Bruker to NIfTI-1 data format, image re-orientation, bias-field correction, brain extraction, region-of-interest segmentation, registration with the Allen Mouse Brain Atlas (CCFv3), functional connectivity analysis (in the folder MRI_proc_data/_Evaluation generated with AIDAconnect_v1.0).

Authors:

Frederique Wieters and Markus Aswendt

datacite.yml
Title Longitudinal (4 wks) T2-weighted MRI and DTI of WT mice with cortical stroke (thromboembolic model) in C57BL/6 mice.
Authors Wieters,Frederique;University of Cologne
Aswendt,Markus;University of Cologne;ORCID:0000-0003-1423-0934
Description Longitudinal MRI including T2-weighted (T2w) and diffusion tensor imaging (DTI) WT mice with cortical stroke lesions induced by injection of thrombin and survival time of 4 weeks (4 wks).
License Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License (https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode)
References
Funding
Keywords Neuroscience
Stroke
Stroke recovery
Thrombin
MRI
Resource Type Dataset