Longitudinal (4 wks) T2-weighted MRI and Diffusion Tensor Imaging (DTI) of WT mice with cortical stroke (photothrombosis model)

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README.md

WT_PT_4wks_T2w_DTI

Longitudinal (4 wks) T2-weighted MRI and Diffusion Tensor Imaging (DTI) of WT mice with cortical stroke (photothrombosis model)

Files:

  • File structure: Study > proc/raw_data > Time point> Group > Subject ID.
    • Time point (Baseline, post stroke days 1-28)
    • Group (Stroke/Sham)
  • Groups:
    • Stroke: SP_T1_1_1, SP_T1_1_2, SP_T1_1_3, SP_T1_2_1, SP_T1_4_1, SP_T1_4_2, SP_T1_4_3, SP_T1_6_1, SP_T1_7_1, SP_T1_11_1, SP_T1_11_2, SP_T1_13_1, SP_T1_23_1, SP_T1_23_2
    • Sham: SP_T1_2_2, SP_T1_2_3, SP_T1_11_3, SP_T1_11_4, SP_T1_12_2, SP_T1_13_4, SP_T1_22_1, SP_T1_22_3
  • raw_data: - contains all raw data in Bruker 2dseq format and the original Bruker folder structure
  • proc_data: - contains all data processed with the AIDAmri_v1.1 pipeline. Processing steps: define stroke masks, convert Bruker to NIfTI-1 data format, image re-orientation, bias-field correction, brain extraction, region-of-interest segmentation, registration with the Allen Mouse Brain Atlas (CCFv3), structural connectivity analysis (in the folder MRI_proc_data/_Evaluation generated with AIDAconnect_v1.0).

Authors:

Niklas Pallast, Marieke Nill, Frederique Wieters, Dirk Wiedermann, and Markus Aswendt.

datacite.yml
Title Longitudinal MRI (T2-weighted and DTI) of WT mice with cortical stroke
Authors Pallast,Niklas;University of Cologne
Nill,Marieke;University of Cologne
Wieters,Frederique;University of Cologne
Wiedermann,Dirk;Max Planck Institute for Metabolism Research
Aswendt,Markus;University of Cologne;ORCID:0000-0003-1423-0934
Description Longitudinal (4 wks) T2-weighted MRI and Diffusion Tensor Imaging (DTI) of WT mice with cortical stroke (photothrombosis model)
License Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License (https://creativecommons.org/licenses/by-nc-sa/4.0/)
References Pallast N, Wieters F, Nill M, Fink GR, Aswendt M. Graph theoretical quantification of white matter reorganization after cortical stroke in mice. Neuroimage. 2020 Aug 15;217:116873. doi: 10.1016/j.neuroimage.2020.116873. Epub 2020 May 5. PMID: 32380139. [doi: 10.1016/j.neuroimage.2020.116873] (IsSupplementTo)
Funding
Keywords Neuroscience
MRI
Stroke
Mouse
Resource Type Dataset