authors:
  -
    firstname: Xiaofeng
    lastname: Wang
    affiliation: 'Department of Neurosurgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan 250014, China'
    id: 'ORCID:0009-0002-4807-4060'
  -
    firstname: Min
    lastname: Chen
    affiliation: 'Department of Radiology, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian 271016, China'
    id: 'ORCID:0000-0003-1702-1820'
  -
    firstname: Yin
    lastname: Shen
    affiliation: 'Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250117, China'
  -
    firstname: Yuming
    lastname: Li
    affiliation: 'Department of Neurosurgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan 250014, China'
  -
    firstname: Shengjie
    lastname: Li
    affiliation: 'Department of Neurosurgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan 250014, China'
  -
    firstname: Yuanhao
    lastname: Xu
    affiliation: 'Centre for Biosystems, Neuroscience, and Nanotechnology, City University of Hong Kong, Hong Kong 999077, China'
    id: 'ORCID:0000-0001-5529-5078'
  -
    firstname: Yu
    lastname: Liu
    affiliation: 'Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250117, China'
  -
    firstname: 'Fei '
    lastname: Su
    affiliation: 'Department of Radiology, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian 271016, China'
    id: 'ORCID:0000-0002-2585-6564'
  -
    firstname: Tao
    lastname: Xin
    affiliation: 'Department of Neurosurgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan 250014, China'
    id: 'ORCID:0000-0002-8797-3002'
title: 'A longitudinal bilateral primary motor cortex electrophysiological and behavior dataset for hemi-parkinsonian rat in response to deep brain stimulation'
description: 'Here we presented an electrophysiological dataset collected from layer V of the primary motor cortex (M1) and the corresponding behavior dataset from normal and hemi-parkinson rats over 5 consecutive weeks. The electrophysiological dataset was constituted by the raw wideband signal, neuronal spikes, and local field potential (LFP) signal. The open-field test was done to evaluate the behavior variation of rats, and the corresponding data was recorded among the entire experimental cycle. We conducted technical validation of this dataset through sorting the spike data to form action potential waveforms and analyzing the spectral power of LFP data, then based on these findings a closed-loop DBS protocol was developed by the oscillation activity response of M1 LFP signal. Additionally, this protocol was applied to the hemi-parkinson rat for five consecutive days while simultaneously recording the electrophysiological data.'
keywords:
  - 'Parkinson’s disease'
  - electrophysiological
  - rat
  - 'closed-loop DBS'
license:
  name: 'Creative Commons CC0 1.0 Public Domain Dedication'
  url: 'https://creativecommons.org/publicdomain/zero/1.0/'
references:
  id: 'doi:tba'
  reftype: IsSupplementTo
  citation: 'Xiaofeng Wang, Min Chen, Yin Shen, Yuming Li, Shengjie Li, Yuanhao Xu, Yu Liu, Fei Su, Tao Xin：A longitudinal electrophysiological and behavior dataset for PD rat in response to deep brain stimulation.Scientific Data, submitted.'
funding:
  - 'Taishan Scholar Project special funding ：tstp20230659'
  - 'Shandong Provincial Natural Science Foundation ：ZR2020QH119'
  - 'Cultivation Fund of National Natural Science Foundation of China in Shandong Provincial Qianfoshan Hospital：QYPY2021NSFC0805'
  - 'Innovation Project of Clinical Science and Technology of Jinan City ：202134047'
resourcetype: Dataset
templateversion: 1.2